Telemedicine’s Past, Present and Future Role in Pediatric Inflammatory Bowel Disease Care
Telemedicine’s Past, Present and Future Role in Pediatric Inflammatory Bowel Disease Care 1024 683 Erin Gregory

A recent study sheds light on how telemedicine’s use during the pandemic has reshaped care delivery for children with IBD.   A recent study published in Journal of Pediatric Gastroenterology and Nutrition utilized electronic medical record data to compare the volume, duration and nature…

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Trauma and Resilience in Youth With Opioid Use and Eating Disorders
Trauma and Resilience in Youth With Opioid Use and Eating Disorders 1024 575 Pam Georgiana

Health care providers should expect patients to have hidden traumas and reduced resilience.   When treating adolescents and young adults in the Substance Use Treatment and Recovery program at Nationwide Children’s, medical director Erin R. McKnight, MD, MPH, noticed that while most of her…

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Nationwide Children’s Research Benefits Kids Everywhere
Nationwide Children’s Research Benefits Kids Everywhere 1024 619 Nationwide Children's

Pediatric research benefits children everywhere. Through the stories below, discover more about the breadth and depth of research at Nationwide Children’s that is improving child health. Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases Not long ago, a diagnosis of molybdenum…

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Improving Medication Adherence and Clinical Outcomes After Hematopoietic Stem Cell Transplant
Improving Medication Adherence and Clinical Outcomes After Hematopoietic Stem Cell Transplant 1024 683 JoAnna Pendergrass, DVM

A clinical trial is evaluating the acceptability and efficacy of a mobile app in improving medication adherence, symptoms and clinical outcomes in pediatric hematopoietic stem cell patients. A research team led by Micah Skeens, PhD, APRN, FAAN, principal investigator in the Center for Biobehavioral…

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Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases
Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases 1024 619 Katie Brind'Amour, PhD, MS, CHES

As new treatments emerge and diagnostics improve, earlier interventions offer infants with rare metabolic and neurodegenerative conditions a future wildly different than ever before. Not long ago, a diagnosis of molybdenum cofactor deficiency (MoCD) type A meant death before kindergarten. Since the FDA approval…

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Turning Complications into Fuel for a New Approach to Better Outcomes
Turning Complications into Fuel for a New Approach to Better Outcomes 1024 418 Alaina Doklovic

A new web application enhances Morbidity and Mortality data storage and actively improves patient care. Morbidity and Mortality (M&M) Conferences are mandated meetings that occur regularly at all academic medical centers and are powerful opportunities for learning and reflection. These conferences have been around…

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Accelerating Advances in Epilepsy Surgery
Accelerating Advances in Epilepsy Surgery 1024 683 Abbie Miller

One program is bringing together clinical care, surgery and research to create a brighter future for children with intractable epilepsy. Childhood-onset epilepsy affects 1% of children worldwide. Up to a third of patients with epilepsy will have medically refractory epilepsy, continuing to have seizures…

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New Frontiers for Data Science in Pediatric Research
New Frontiers for Data Science in Pediatric Research 1024 577 Peter White, PhD

From discovery science to population health, researchers generate masses of data that hold immense potential to transform pediatric research, diagnostics, treatments and even guide disease prevention strategies. To make sense of this data deluge, we’ve been harnessing the power of cloud computing and cutting-edge…

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Unraveling the Genetic Mystery Behind a Rare Pediatric Disease
Unraveling the Genetic Mystery Behind a Rare Pediatric Disease 980 429 Wendy Margolin

Prune belly syndrome (PBS) is a rare, congenital urologic disease, affecting an estimated 1 out of 50,000 births. While most urologists will see fewer than three cases of PBS in their careers, Nationwide Children’s Hospital’s Linda Baker, MD, has treated more than 50 patients…

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The First 3 Years With PBS: Bryson’s Story
The First 3 Years With PBS: Bryson’s Story 953 269 Wendy Margolin

The first time Andrea Williams met her new baby was four days after his birth. Baby Bryson was born with the rare congenital disorder, prune belly syndrome (PBS), and was rushed to the Nationwide Children’s Hospital NICU immediately after birth. His enlarged belly meant…

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Connecting Well-being to Compassionate Care in Pediatric Residents
Connecting Well-being to Compassionate Care in Pediatric Residents 1024 683 Madison Storm

A multicenter study identified several well-being factors associated with pediatric residents’ confidence in providing calm, compassionate care to patients. Suzanne Reed, MD, has been interested in medical education since her training as a medical student. Captivated by the academic side of education, Dr. Reed…

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Proton Therapy – A New Era of Cancer Therapy for Children
Proton Therapy – A New Era of Cancer Therapy for Children 1024 683 Abbie Miller

Proton therapy offers benefits over traditional photon radiation therapy. Using proton therapy, doctors can give more specific, concentrated doses of radiation with less risk and damage to the surrounding tissue. Proton therapy is an advanced type of radiation treatment that uses protons instead of…

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Practical Advice for Investigator-Initiated Trials
Practical Advice for Investigator-Initiated Trials 1024 363 Lauren Dembeck

Investigator-initiated trials play a crucial role in advancing medical research and contributing to evidence-based medicine. These trials are initiated, designed and conducted by researchers, often physicians or scientists, rather than by pharmaceutical or biotechnology companies. They allow researchers to explore specific hypotheses, novel interventions…

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New National “Vital Signs” to Measure Population-wide Pediatric Health
New National “Vital Signs” to Measure Population-wide Pediatric Health 1024 683 Jeb Phillips

In 2017, an opinion piece in JAMA Pediatrics started this way: “We call for a national effort to develop a parsimonious set of quality and outcome measures for (all) children.” And now, for perhaps the first time in American pediatrics, that “parsimonious set: has been…

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Featured Researcher – Rajan Thakkar, MD
Featured Researcher – Rajan Thakkar, MD 150 150 Alaina Doklovic

Rajan K. Thakkar, MD, FACS, is a pediatric surgeon, the Trauma Medical Director, and the co-Director of the Burn Center at Nationwide Children’s Hospital. He is an associate professor of Surgery and Pediatrics at The Ohio State University College of Medicine and is a…

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Supporting Optimal Developmental Outcomes After Neonatal Opioid Withdrawal Syndrome
Supporting Optimal Developmental Outcomes After Neonatal Opioid Withdrawal Syndrome 1024 575 Abbie Miller

Children with prenatal opioid exposure have a higher risk for developmental and behavioral concerns. Prenatal opioid exposure is still far too common. Experts estimate that one infant who has been exposed to opioids is born every 15 minutes in the United States.  While standard…

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Scalable Delivery of Universal Suicide Prevention in Schools
Scalable Delivery of Universal Suicide Prevention in Schools 1024 657 Pam Georgiana

Implementing the Signs of Suicide (SOS) Prevention and Screening Program   Suicide is the second-leading cause of death among youth ages 10 to 19 years, and data indicate no sign of it decreasing as a major public health issue. While acute care and crisis…

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Infliximab Biosimilars Improve Growth Outcomes in Children With Inflammatory Bowel Disease
Infliximab Biosimilars Improve Growth Outcomes in Children With Inflammatory Bowel Disease 1024 683 Mary Bates, PhD

Treatment with either the infliximab originator or a biosimilar improves clinical and growth outcomes. In a new study, researchers at Nationwide Children’s Hospital report that children with inflammatory bowel disease showed similar growth and clinical outcomes whether they were treated with the infliximab originator…

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New Approach to Understanding Slow Oscillations in the Sleeping Brain
New Approach to Understanding Slow Oscillations in the Sleeping Brain 150 150 Jessica Nye, PhD

Investigators have proposed a novel model-based approach that leverages data generated during sleep to mimic global slow oscillations in the sleeping brain with closed-loop (cl) Transcranial Alternating Current Stimulation (tACS). “We’re really interested in the sleeping brain because as we develop, the brain is…

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Integrating PCOS Research and Clinical Care for Adolescents
Integrating PCOS Research and Clinical Care for Adolescents 1024 575 Pam Georgiana

Researchers at Nationwide Children’s are participating in building the first-ever national registry of adolescent Polycystic Ovary Syndrome (PCOS) patient data through a National Institutes of Health (NIH)-funded research grant. The grant will collect patient data from more than 12 multidisciplinary PCOS clinics, including Nationwide…

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