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Monthly Archives :

March 2020

From Lab Work to “Home Work:” Tips on the Transition to Work From Home
 From Lab Work to “Home Work:” Tips on the Transition to Work From Home 1024 683 Adrianna Matos-Nieves
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PhD candidate Adrianna Matos-Nieves shares tips for research employees who are suddenly finding themselves transitioning from the wet lab to their home office. PhD students have a significant advantage when enduring coronavirus-imposed social distancing. We decided to do it voluntarily many years prior. But in all seriousness, the transition to working from home can be…

What Could COVID-19 Mean for Pediatrics?
 What Could COVID-19 Mean for Pediatrics? 1024 683 Abbie Miller
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As COVID-19 spreads across the globe, experts are digging into the data and establishing protocols to better understand the illness in the context of pediatrics. As COVID-19, the illness caused by a novel coronavirus, has reached pandemic status, life has changed dramatically. At Nationwide Children’s Hospital, the halls are uncharacteristically quiet as a “stay at…

Health Care and Medication Use Among Adolescents with Opioid Use Disorder in Ohio
 Health Care and Medication Use Among Adolescents with Opioid Use Disorder in Ohio 1024 575 Abbie Miller
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From Ohio – a state in the heart of the opioid crisis – a new study on the medications prescribed to teens with opioid use disorder. A new study from researchers in the Center for Innovation in Pediatric Practice at the Abigail Wexner Research Institute at Nationwide Children’s Hospital, recently published in Journal of Adolescent Health,…

Study Shows Promising Host-Targeted Approach for the Prevention and Cure of Gonorrhoea in Women
 Study Shows Promising Host-Targeted Approach for the Prevention and Cure of Gonorrhoea in Women 1024 683 Nationwide Children's
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In research published in mBio, researchers from the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital and Griffith University’s Institute for Glycomics have discovered non-antibiotic (host-targeted) therapies for the effective treatment of Neisseria gonorrhoeae infections by repurposing existing drugs. Gonorrhoea is the second most commonly reported sexually transmitted infection (STI). The Centers for Disease Control and…

A Natural History of Duchenne Muscular Dystrophy in Boys 3 to 6 Years Old
 A Natural History of Duchenne Muscular Dystrophy in Boys 3 to 6 Years Old 1024 575 Abbie Miller
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boy with muscular dystrophy completing walk test

A prospective, multicenter study following 153 boys younger than 6 years old documents disease progression of Duchenne muscular dystrophy. Duchenne muscular dystrophy is the most common inherited neuromuscular disorder that affects all races and ethnicities. It affects males, occurring in 1/3,600 live-born infant boys. While some affected newborns may have mild hypotonia, other symptoms are rarely…

New Celiac Care Index Improves Adherence to Care Guidelines
 New Celiac Care Index Improves Adherence to Care Guidelines 1024 575 Lauren Dembeck
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The recent implementation of a Celiac Care Index (CCI) at Nationwide Children’s Hospital resulted in improved adherence to published care guidelines, reduced variability in baseline evaluations, and indicated potentially unnecessary baseline laboratory tests for further evaluation. The study, which was published in The Journal of Pediatrics, describes the quality improvement (QI) strategy implemented at the hospital.…

A Decade of Healthy Homes
 A Decade of Healthy Homes 1024 683 Kelly Kelleher, MD, MPH
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Dr. Kelleher and Rev. John Edgar, executive director and pastor emeritus, Church and Community for All People, discuss the first decade of a collaboration aimed to take on housing issues in the South Side of Columbus as a way to improve health outcomes and answer the question: What’s on the horizon? The last decade has…

New Application of Nuclear Imaging in the Legs May Enable Early Detection of Cardiovascular Problems
 New Application of Nuclear Imaging in the Legs May Enable Early Detection of Cardiovascular Problems 150 150 Katie Brind'Amour, PhD, MS, CHES
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Researchers have used a non-invasive imaging modality to quantify perfusion reserve in specific muscles of the extremities — a novel approach with numerous potential clinical applications Researchers have shown for the first time that SPECT/CT imaging can be used to quantify perfusion reserve of specific muscle groups in the lower limbs, which they directly related…

How Does a Children’s Hospital Excel in the Discovery and Development of New Therapies?
 How Does a Children’s Hospital Excel in the Discovery and Development of New Therapies? 1024 575 Abbie Miller
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conceptual art of DNA

A conversation with Dennis Durbin, MD, MSCE chief scientific officer, Abigail Wexner Research Institute, Nationwide Children’s Hospital Nationwide Children’s has become an epicenter for gene therapy discovery and development. The discovery in 2009 that adeno-associated virus (AAV) could cross the blood-brain barrier was a milestone in the development of dozens of gene therapy products for neuromuscular…

Keeping Options Open in Complex Pediatric Nephrolithiasis
 Keeping Options Open in Complex Pediatric Nephrolithiasis 1024 575 Lauren Dembeck
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Urologists in the Pediatric Urology Midwest Alliance recently looked at how endoscopic assisted robotic pyelolithotomy could reduce the number of procedures for children with ureteropelvic junction obstruction. The Pediatric Urology Midwest Alliance (PUMA) recently published a new report demonstrating that endoscopic assisted robotic pyelolithotomy (EARP) is an acceptable treatment option for complex cases of pediatric…