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Monthly Archives :

March 2021

Investigating Youth Suicides Among Children Involved With the Welfare System
 Investigating Youth Suicides Among Children Involved With the Welfare System 1024 683 Natalie Wilson
By: Natalie Wilson
silhouette girl portrait

Youth with child welfare involvement are at an elevated risk for suicide but may benefit from suicide prevention interventions targeting health care settings and family-preservation. Suicide is the second leading cause of death among youth aged 5 to 21 years in the United States. Between 2010 and 2019, suicide rates among this group increased 40%.…

Featured Researcher — Jingzhen Ginger Yang, PhD, MPH
 Featured Researcher — Jingzhen Ginger Yang, PhD, MPH 150 150 Natalie Wilson
By: Natalie Wilson

Dr. Jingzhen (Ginger) Yang, a principal investigator in the Center for Injury Research and Policy at the Abigail Wexner Research Institute at Nationwide Children’s Hospital, has a national and international reputation as a leader in pediatric injury prevention research. Currently, Dr. Yang is directing three NIH-funded R01 studies, and her research focuses on two areas: improving sports-related concussion recovery among children and…

Incidence and Impact of Acute Kidney Injury in Patients With Hypoplastic Left Heart Syndrome
 Incidence and Impact of Acute Kidney Injury in Patients With Hypoplastic Left Heart Syndrome 150 150 Abbie Miller
By: Abbie Miller

While incidence of severe kidney injury after surgery for hypoplastic left heart syndrome is low, it may be linked to increased 30-day mortality. Acute kidney injury – the abrupt decline of renal function – following pediatric heart surgery leads to worse outcomes, including increased mortality. The overall incidence of acute kidney injury (AKI) after pediatric…

Novel Nitric Oxide-Mediated Mechanism Facilitates Calcific Aortic Valve Disease
 Novel Nitric Oxide-Mediated Mechanism Facilitates Calcific Aortic Valve Disease 1024 752 Lauren Dembeck
By: Lauren Dembeck
Top-down view of heart valves

The novel pathway could be targeted to prevent or reverse aortic valve calcification in humans. Researchers have recently described a novel nitric oxide-mediated mechanism in calcific aortic valve disease that involves the ubiqutin-proteasome pathway, and its modulation in animal models was shown to cause aortic valve calcification. The pathway could potentially be modulated to prevent…

Natural Progression of Duchenne Muscular Dystrophy for Boys Taking Long-Term Steroid Therapy
 Natural Progression of Duchenne Muscular Dystrophy for Boys Taking Long-Term Steroid Therapy 1024 575 Mary Bates, PhD
By: Mary Bates, PhD
boy with muscular dystrophy completing walk test

New data define expected motor performance at different ages and will help in clinical trial design and interpretation. Duchenne muscular dystrophy (DMD) is a devastating diagnosis, but there are many potential treatments in various stages of development. Clinical trials now target boys with DMD who are 4-8 years old, as it appears that early intervention…

Inverse Relationship Between Age and Dose of Blood Thinners for Children
 Inverse Relationship Between Age and Dose of Blood Thinners for Children 1024 495 Natalie Wilson
By: Natalie Wilson
blood cells

Infants and young children require higher doses of enoxaparin to treat blood clots than do older children. A blood clot, or thrombosis, isn’t a common problem in children, but it can be a dangerous one. Without proper treatment, a thrombosis can cause a host of long-term problems up to and including permanent damage to patients’…

Neurodevelopmental Trajectory in Infants With Neonatal Opioid Withdrawal Syndrome
 Neurodevelopmental Trajectory in Infants With Neonatal Opioid Withdrawal Syndrome 1024 575 Mary Bates, PhD
By: Mary Bates, PhD

Infants exposed to opioids in utero begin showing cognitive and language deficits in their second year. In a new study, researchers from Nationwide Children’s Hospital report the neurodevelopmental outcomes of infants with pharmacologically treated neonatal opioid withdrawal syndrome (NOWS, formerly called neonatal abstinence syndrome, or NAS) through 2 years of age. The results showed that…

Increasing the Use of the Teach-Back Method in Asthma Education
 Increasing the Use of the Teach-Back Method in Asthma Education 1024 575 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM
Lisa Ulrich standing in hospital hallway

A standardized approach to asthma education using the teach-back method helps respiratory therapists effectively address common issues with asthma management in pediatric patients. For the 8% of children and adults in the United States who have asthma, effective asthma education is essential to adequate disease management. Unfortunately, written asthma action plans (AAP) alone may be…