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Monthly Archives :

May 2018

Improving Feeding and Growth in Children With Cleft Palate
 Improving Feeding and Growth in Children With Cleft Palate 1024 684 Mary Bates, PhD
By: Mary Bates, PhD
Image of a hand hovering above an infant formula bottle with a measuring spoon filled with powdered formula

Targeted interventions result in improved feeding efficiency and growth in infants with cleft lip and/or palate. Cleft lip and/or palate is a relatively common birth defect that occurs when certain parts of the face and mouth fail to fuse during development. Infants with the condition can struggle to suck or extract liquid from the breast…

How to Make a Viral Vector
 How to Make a Viral Vector 150 150 Abbie Miller
By: Abbie Miller

The Research Institute at Nationwide Children’s Hospital is the home to a current Good Manufacturing Practices (cGMP) Clinical Manufacturing Facility (CMF) that operates according to FDA cGMP Guidelines to ensure the safety of manufactured biologic products. The Space The CMF is a 9000-sq-ft space, including a 7500-sq-ft clean room suite with ISO Class 5/7/8 spaces…

Bridging the Gap Between the Genomics Lab and the Cardiology Clinic: CardioGX for Phenotype-Driven Variant Analysis
 Bridging the Gap Between the Genomics Lab and the Cardiology Clinic: CardioGX for Phenotype-Driven Variant Analysis 150 150 Abbie Miller
By: Abbie Miller

The cloud-based platform is a free tool that empowers clinicians and fosters collaboration to find new genetic mutations that cause heart disease. Finding ways to support clinicians and researchers in accessing and utilizing genomic data is paramount to incorporating genomics into clinical care. CardioGX (CardioGenomics eXchange commons) is an interactive web application designed to help clinicians and…

Age-Related Racial Disparities in Suicide Rates Among Youth Ages 5 to 17 Years
 Age-Related Racial Disparities in Suicide Rates Among Youth Ages 5 to 17 Years 150 150 Abbie Miller
By: Abbie Miller

Under the age of 13, suicide rates are roughly double for black children compared with white children. Suicide rates in the United States have traditionally been higher among whites than blacks across all age groups. However, a new study from researchers at Nationwide Children’s Hospital and collaborators published in JAMA Pediatrics shows that racial disparities in suicide…

Cannabis-Derived Treatment Can Significantly Reduce Seizures in Hard-To-Treat Childhood Epilepsy
 Cannabis-Derived Treatment Can Significantly Reduce Seizures in Hard-To-Treat Childhood Epilepsy 1024 683 Jeb Phillips
By: Jeb Phillips
Dr. Anup D. Patel, MD standing in a hallway wearing a white lab coat

A new study shows that cannabidiol is effective in children with Lennox-Gastaut syndrome. Children with Lennox-Gastaut syndrome can have hundreds of brief seizures every day. This complex form of epilepsy often does not respond to conventional epilepsy medication, leaving children at serious risk of injury from their seizures, or confined to wheelchairs and beds. An international…

Room for Improvement: Heart Catheterization Risks in Young Patients With Pulmonary Hypertension
 Room for Improvement: Heart Catheterization Risks in Young Patients With Pulmonary Hypertension 1024 575 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES
Illustration of heart, CAVD

Identifying risk factors for cardiac catheterization complications offers physicians a way to improve pulmonary hypertension care. Up until a few years ago, cardiac catheterization in patients with pulmonary hypertension was considered a low-risk procedure for children and young adults. Some of the country’s best physicians had published studies showing very few complications among hundreds of…

How Primary Care Providers Can Help Justice-Involved Youth
 How Primary Care Providers Can Help Justice-Involved Youth 1024 683 Deena Chisolm, PhD
By: Deena Chisolm, PhD
Deena Chisolm, PhD, smiles while walking down a brightly lit hospital corridor, holding a tablet and wearing a white coat.

Deena Chisolm, PhD, shares how primary care physicians can support youth who may experience behavioral health issues related to justice involvement. For most people in the United States, the law enforcement and criminal justice systems support a sense of safety and security.  However, for some populations, particularly people of color, perceptions of and interactions with…

The Pediatrician’s Role in Health and Hope after Trauma
 The Pediatrician’s Role in Health and Hope after Trauma 150 150 Anna Kerlek, MD
By: Anna Kerlek, MD

A primary care provider’s ability to identify and treat symptoms associated with trauma can increase positive outcomes for patients and families. Almost two-thirds of the children and their caretakers in your office have experienced at least one trauma. Many have experienced more. As a primary care provider, you can provide early intervention and support for…

A Revolution in Deformity Correction Plus Limb Lengthening
 A Revolution in Deformity Correction Plus Limb Lengthening 1024 683 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES
Dr. Christopher A. Iobst, MD, in a white lab coat in a white medical hallway

Orthopedic surgeons demonstrate that acute deformity correction and gradual limb lengthening can be accomplished simultaneously using an internal lengthening nail. In the past, limb lengthening and femoral deformity correction meant a long, painful, very visible process — an external fixator with manual adjusters, a knee that was difficult to bend, high infection risk and more.…