Monthly Archives :

May 2018

Improving Feeding and Growth in Children With Cleft Palate
Improving Feeding and Growth in Children With Cleft Palate 1024 575 Mary Bates, PhD
Black and white photo of baby bottle with formula on the table in front of a simple background

Targeted interventions result in improved feeding efficiency and growth in infants with cleft lip and/or palate. Cleft lip and/or palate is a relatively common birth defect that occurs when certain parts of the face and mouth fail to fuse during development. Infants with the condition can struggle to suck or extract liquid from the breast…

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How to Make a Viral Vector
How to Make a Viral Vector 150 150 Abbie Roth

The Research Institute at Nationwide Children’s Hospital is the home to a current Good Manufacturing Practices (cGMP) Clinical Manufacturing Facility (CMF) that operates according to FDA cGMP Guidelines to ensure the safety of manufactured biologic products. The Space The CMF is a 9000-sq-ft space, including a 7500-sq-ft clean room suite with ISO Class 5/7/8 spaces…

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Bridging the Gap Between the Genomics Lab and the Cardiology Clinic: CardioGX for Phenotype-Driven Variant Analysis
Bridging the Gap Between the Genomics Lab and the Cardiology Clinic: CardioGX for Phenotype-Driven Variant Analysis 150 150 Abbie Roth

The cloud-based platform is a free tool that empowers clinicians and fosters collaboration to find new genetic mutations that cause heart disease. Finding ways to support clinicians and researchers in accessing and utilizing genomic data is paramount to incorporating genomics into clinical care. CardioGX (CardioGenomics eXchange commons) is an interactive web application designed to help clinicians and…

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Age-Related Racial Disparities in Suicide Rates Among Youth Ages 5 to 17 Years
Age-Related Racial Disparities in Suicide Rates Among Youth Ages 5 to 17 Years 150 150 Abbie Roth

Under the age of 13, suicide rates are roughly double for black children compared with white children. Suicide rates in the United States have traditionally been higher among whites than blacks across all age groups. However, a new study from researchers at Nationwide Children’s Hospital and collaborators published in JAMA Pediatrics shows that racial disparities in suicide…

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Cannabis-Derived Treatment Can Significantly Reduce Seizures in Hard-To-Treat Childhood Epilepsy
Cannabis-Derived Treatment Can Significantly Reduce Seizures in Hard-To-Treat Childhood Epilepsy 150 150 Jeb Phillips

A new study shows that cannabidiol is effective in children with Lennox-Gastaut syndrome. Children with Lennox-Gastaut syndrome can have hundreds of brief seizures every day. This complex form of epilepsy often does not respond to conventional epilepsy medication, leaving children at serious risk of injury from their seizures, or confined to wheelchairs and beds. An international…

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Room for Improvement: Heart Catheterization Risks in Young Patients With Pulmonary Hypertension
Room for Improvement: Heart Catheterization Risks in Young Patients With Pulmonary Hypertension 1024 575 Katie Brind'Amour, PhD, MS, CHES
Illustration of heart, CAVD

Identifying risk factors for cardiac catheterization complications offers physicians a way to improve pulmonary hypertension care. Up until a few years ago, cardiac catheterization in patients with pulmonary hypertension was considered a low-risk procedure for children and young adults. Some of the country’s best physicians had published studies showing very few complications among hundreds of…

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How Primary Care Providers Can Help Justice-Involved Youth
How Primary Care Providers Can Help Justice-Involved Youth 1024 683 Deena Chisolm, PhD

Deena Chisolm, PhD, shares how primary care physicians can support youth who may experience behavioral health issues related to justice involvement. For most people in the United States, the law enforcement and criminal justice systems support a sense of safety and security.  However, for some populations, particularly people of color, perceptions of and interactions with…

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The Pediatrician’s Role in Health and Hope after Trauma
The Pediatrician’s Role in Health and Hope after Trauma 150 150 Anna Kerlek, MD

A primary care provider’s ability to identify and treat symptoms associated with trauma can increase positive outcomes for patients and families. Almost two-thirds of the children and their caretakers in your office have experienced at least one trauma. Many have experienced more. As a primary care provider, you can provide early intervention and support for…

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A Revolution in Deformity Correction Plus Limb Lengthening
A Revolution in Deformity Correction Plus Limb Lengthening 1024 575 Katie Brind'Amour, PhD, MS, CHES

Orthopedic surgeons demonstrate that acute deformity correction and gradual limb lengthening can be accomplished simultaneously using an internal lengthening nail. In the past, limb lengthening and femoral deformity correction meant a long, painful, very visible process — an external fixator with manual adjusters, a knee that was difficult to bend, high infection risk and more.…

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