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Monthly Archives :

June 2024

Featured Researcher: Henry Xiang, MD, MPH, PhD, MBA
 Featured Researcher: Henry Xiang, MD, MPH, PhD, MBA 150 150 Alaina Doklovic
By: Alaina Doklovic

Dr. Henry Xiang is the founding Director of the Center for Pediatric Trauma Research of the Abigail Wexner Research Institute at Nationwide Children’s Hospital. He is also a tenured full professor at the Ohio State University College of Medicine. Dr. Xiang directs the Pilot Translational and Clinical Studies Program at the NIH-funded Ohio State University…

Clinical Differences in Early-Onset and Adolescent-Onset Rumination Syndrome
 Clinical Differences in Early-Onset and Adolescent-Onset Rumination Syndrome 1024 683 Mary Bates, PhD
By: Mary Bates, PhD

Study suggests rumination syndrome in young children is less severe initially and improves over time.   Early-onset rumination syndrome is clinically distinct from adolescent-onset rumination syndrome, according to a new report out of Nationwide Children’s Hospital. In this largest study of pediatric patients with rumination syndrome to date, researchers found differences in sex distribution, co-occurring…

What Pediatricians Need to Know About Over-the-Counter Oral Contraception
 What Pediatricians Need to Know About Over-the-Counter Oral Contraception 1024 683 Elise Berlan, MD, MPH and Caroline Weingart, MD
By: Elise Berlan, MD, MPH and Caroline Weingart, MD

The first over-the-counter contraceptive pill – the Opill® – is currently available in retail outlets and online. The FDA approved the sale of Opill® (nongestural 0.075mg), the first over-the-counter birth control pill without age restrictions, in July 2023. Now, nearly a year later, it will be available soon in retail outlets and online. As a…

Understanding How Youths With Autism Make the Move to Adult Health Care
 Understanding How Youths With Autism Make the Move to Adult Health Care 1024 683 Mary Bates, PhD
By: Mary Bates, PhD

Study finds overlap in the utilization of pediatric and adult health care is the norm. In a new study, researchers from Nationwide Children’s Hospital and The Ohio State University teamed up to better understand how adolescents and young adults with autism navigate the transition from pediatric to adult health care. “We wanted to characterize the…

Refining the Role of Basal Urothelial Cells in Bladder Development
 Refining the Role of Basal Urothelial Cells in Bladder Development 1024 683 Jessica Nye, PhD
By: Jessica Nye, PhD

Basal keratin 5 urothelial cells (K5-UCs) were found to be age-restricted progenitors in bladders and their progenitor potential could be rescued by exogenous proliferative cues.   “The identity of the bladder urothelium progenitor is controversial and confounded by slow turnover, and a low mitotic index during homeostasis,” says Ashley R. Jackson, PhD, principal investigator in…

How Does Hodgkin Lymphoma Differ With Age?
 How Does Hodgkin Lymphoma Differ With Age? 150 150 Pam Georgiana
By: Pam Georgiana

A new study reveals age-related differences in pathology and medical management. When Anthony N. Audino, MD, a pediatric oncologist in the Division of Pediatric Hematology/Oncology/BMT at Nationwide Children’s, first met a preschool-aged patient with Hodgkin lymphoma, he was surprised. “It was startling to see someone so young with this disease because it’s typically diagnosed between…

New Study Demonstrates Potential for a Gene Therapy for Vanishing White Matter Disease
 New Study Demonstrates Potential for a Gene Therapy for Vanishing White Matter Disease 1024 552 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

The research, conducted in mouse models, shows promising safety and efficacy for a currently incurable, life-limiting condition. Researchers at Nationwide Children’s Hospital have confirmed initial safety and efficacy data for a gene supplementation therapy for Vanishing White Matter (VWM) disease in mouse models. Testing multiple versions of therapy in two separate mouse models representing different…

Breaking the Cycle of Chronic Pain and Discomfort in Young Patients
 Breaking the Cycle of Chronic Pain and Discomfort in Young Patients 1024 575 Pam Georgiana
By: Pam Georgiana
Teen girl with backpack

The Comfort Ability Program at Nationwide Children’s brings specialized care to patients with chronic pain and discomfort. In January 2023, the wait for patients to see a pediatric pain psychologist at Nationwide Children’s was approximately nine months. This delay was due to the limited number of providers available. While they waited for treatment, these young…

Investigating a Minimally Invasive Alternative to Surgery for Transverse Aortic Arch Obstruction
 Investigating a Minimally Invasive Alternative to Surgery for Transverse Aortic Arch Obstruction 150 150 Erin Gregory
By: Erin Gregory

A new study evaluates the safety and efficacy of percutaneous balloon-expandable stents for transverse aortic arch obstruction, a form of congenital heart disease. A new study published in Circulation: Cardiovascular Interventions, conducted by Arash Salavitabar, MD, FSCAI, FPICS, FACC, FAAP, a congenital interventional cardiologist at Nationwide Children’s Hospital, and colleagues, evaluates the efficacy and safety…

School-Based Health Equity Initiative Improves T1D Management in Students
 School-Based Health Equity Initiative Improves T1D Management in Students 1024 683 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

The Diabetes and School Health program is a school-based health equity initiative that has helped improve Type 1 diabetes management for students and increase confidence among school staff and caregivers in providing diabetes care. Children with Type 1 diabetes (T1D) face myriad daily challenges in managing their disease, which can be compounded if their home…

Surgical Repair of Traumatic Hip Dislocations With Acetabular “Fleck” Signs
 Surgical Repair of Traumatic Hip Dislocations With Acetabular “Fleck” Signs 1024 683 Mary Bates, PhD
By: Mary Bates, PhD
Kevin Klingele, MD

Surgical hip dislocation with open labral repair produced excellent clinical outcomes in pediatric patients. The acetabular “fleck” sign is a radiographic finding indicative of significant labral injury in young patients with traumatic hip dislocations. In a new study, researchers from Nationwide Children’s Hospital show that treatment by surgical hip dislocation with open labral repair leads…