What Pediatric Endocrinologists Need to Know About Diabetes in the Age of GLP-1s
What Pediatric Endocrinologists Need to Know About Diabetes in the Age of GLP-1s 1024 683 Erin Gregory

GLP-1 receptor agonists such as Ozempic (semaglutide) offer new opportunities for managing pediatric diabetes and obesity. These medications target insulin resistance and related comorbidities, but their use raises questions about safety, access and ethical considerations. In the following interview, Leena Mamilly, MD, and Rohan…

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Real-Time Arrhythmia Detection in Adults With Fontan Palliation
Real-Time Arrhythmia Detection in Adults With Fontan Palliation 1024 683 Pam Georgiana

Evaluating the Utility and Accuracy of Patient-Driven Wearable EKG Monitoring Devices Patient-driven diagnostic wearables, such as personal EKG devices, are popular among adults interested in heart health. However, little is known about the accuracy of these devices for adults with congenital heart disease. “Research…

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How Accurate is Pediatric Bipolar Disorder Testing?
How Accurate is Pediatric Bipolar Disorder Testing? 1024 555 JoAnna Pendergrass, DVM

Symptom-based bipolar disorder tests accurately diagnose pediatric bipolar disorder, with parent-reported tests being among the most accurate. According to a systematic review and meta-analysis of studies evaluating the diagnostic accuracy of bipolar disorder index tests, parent-reported tests are more accurate than self- or teacher-reported…

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Improving Pediatric Clinical Trials by Incorporating Parent Input
Improving Pediatric Clinical Trials by Incorporating Parent Input 1024 681 Katie Brind'Amour, PhD, MS, CHES

A Parent Council in an ongoing pediatric stroke rehabilitation trial provides important insights into how parent involvement can inform and enrich the research process. While the need for diverse and inclusive clinical trial populations has been acknowledged for the last few decades, the value…

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Treatment for Substance Use Disorder in the Synthetic Opioid Era
Treatment for Substance Use Disorder in the Synthetic Opioid Era 1024 683 Alaina Doklovic

Medications for opioid use disorder (MOUD) is the recommended first line treatment for adolescents with opioid use disorder (OUD), the chronic use of opioids and/or synthetic opioids that causes clinically significant distress or impairment. Buprenorphine is the most accessible medication for MOUD. Studies show…

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Introducing the Fourth Wave of the Drug Epidemic
Introducing the Fourth Wave of the Drug Epidemic 1024 575 Alaina Doklovic

Drug overdoses and poisoning are the third leading cause of pediatric death. In recent years, there has been a dramatic increase in the number of fentanyl-related overdoses, with 15-19 year olds being the most affected. In the Ohio illicit drug supply, as shared by…

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Harm Reduction: Meeting Patients With Substance Use Disorders Where They Are
Harm Reduction: Meeting Patients With Substance Use Disorders Where They Are 1024 768 Alaina Doklovic

According to the U.S. Department of Health and Human Services, fewer than 10% of adolescents with a substance use disorder receive care. Of those 10%, many are not ready to engage in treatment. They are often brought in by a parent or guardian. Harm…

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Largest Pediatric ECMO Repository in the United States Celebrates 10 Years of Research
Largest Pediatric ECMO Repository in the United States Celebrates 10 Years of Research 1024 537 Abbie Miller

The ECMO Repository at Nationwide Children’s Hospital is the first and larges of its kind in children’s hospitals in the United States. In December 2014, The Heart Center and Center for Cardiovascular Research at Nationwide Children’s Hospital launched an initiative to prospectively collect biologic…

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Filling the Pipeline for Behavioral Health Professionals
Filling the Pipeline for Behavioral Health Professionals 150 150 Abbie Miller and Shannon Caldwell

Brittany Schaffner, IMFT-S, LPCC-S, shares how a new college course and professional resources are helping more students meet the need for behavioral health care in pediatrics. Tell us about your role at Nationwide Children’s Hospital. I’m a behavioral health clinical training supervisor here at…

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Nephrotoxic-Associated Acute Kidney Injury (NAKI) Is Avoidable
Nephrotoxic-Associated Acute Kidney Injury (NAKI) Is Avoidable 375 280 Pam Georgiana

Quality improvement initiative at Nationwide Children’s Hospital leads to significant reductions in NAKI. Nephrotoxic-associated acute kidney injury (NAKI) — an under-recognized but serious risk in pediatric hospital care — affects up to 25% of hospitalized children. It occurs when medications or toxins reduce kidney…

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Meet Prof Eileen Africa: Fulbright Scholar and Sports Medicine Expert
Meet Prof Eileen Africa: Fulbright Scholar and Sports Medicine Expert 1024 683 Abbie Miller

Prof Eileen Africa, an associate professor in the Division of Movement Science and Exercise Therapy in the Department of Exercise, Sport, and Lifestyle Medicine at Stellenbosch University in South Africa and a Fulbright scholar, recently visited Nationwide Children’s to work with Dr. James MacDonald…

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Meet Antonio Cabrera, MD, Chief of Cardiology at Nationwide Children’s Hospital
Meet Antonio Cabrera, MD, Chief of Cardiology at Nationwide Children’s Hospital 150 150 Abbie Miller

Antonio Cabrera, MD, FAAP, FAHA, FACC, FHFSA, is the division chief of cardiology and co-director of the Heart Center. He is a professor of pediatrics at The Ohio State University and currently holds the Nationwide George H. Dunlap Endowed Chair in Pediatric Cardiology. Previously,…

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Bridging the Fertility Awareness Gap in Adolescents With PCOS
Bridging the Fertility Awareness Gap in Adolescents With PCOS 1024 683 Pam Georgiana

Assessing knowledge, concerns and quality of life to inform early clinical counseling While polycystic ovary syndrome (PCOS) is common in adolescent females, little is known about how the potential for long-term complications like infertility affect young patients’ well-being. Research with adult PCOS patients has…

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A Novel EEG Evaluation Method for Children With Infantile Spasms
A Novel EEG Evaluation Method for Children With Infantile Spasms 1024 677 Lauren Dembeck

Clinician-researchers have developed a rapid training program to learn the BASED score, a novel EEG evaluation method. The easily accessible training program allows clinicians to reliably determine the response to treatment. Infantile epileptic spasms syndrome is a severe form of early childhood epilepsy. Onset…

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Baby in NICU
The Nurse Perception of Infant Condition (NPIC) Scale: A Tool for NICU Nurses to Evaluate Neonatal Well-being
The Nurse Perception of Infant Condition (NPIC) Scale: A Tool for NICU Nurses to Evaluate Neonatal Well-being 1024 683 Jessica Nye, PhD

Investigators from Nationwide Children’s Hospital developed a tool for nurses to use when assessing a neonate’s wellbeing, called the Nurse Perception of Infant Condition (NPIC) Scale. “For neonates, it was hard to find a scale that was relevant and would allow us to measure…

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Establishing Meaningful Clinical Outcome Measures for Gastrointestinal Symptoms in Cystic Fibrosis
Establishing Meaningful Clinical Outcome Measures for Gastrointestinal Symptoms in Cystic Fibrosis 1024 683 Lauren Dembeck

Understanding the minimal clinically important differences of PROMs is crucial in interpreting results in clinical trials. Patient-reported outcome measures (PROMs) are a set of standardized questions that directly assess the patient’s perspective of their symptoms and quality of life to better understand their experience…

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Black Youth Experience Disparities in Care for First-Episode Psychosis in Ohio
Black Youth Experience Disparities in Care for First-Episode Psychosis in Ohio 1024 683 Jessica Nye, PhD

Black youth enrolled in Medicaid were more likely to experience a first-episode psychosis (FEP) event and be diagnosed with schizophrenia spectrum disorder but less likely to receive key early intervention services than White youth.   “It’s been known for a long time, especially in…

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Childhood-Onset Rumination Syndrome: Insights from 15 Years of Research
Childhood-Onset Rumination Syndrome: Insights from 15 Years of Research 1024 680 Pam Georgiana

Education is needed to improve diagnostic timelines and treatment outcomes for pediatric patients. Childhood-onset rumination syndrome presents significant diagnostic challenges, even for gastroenterologists. Physicians often misdiagnose the symptoms as gastroesophageal reflux disease. Initial treatments frequently fail, leading to delays in accurate diagnosis. Patients can…

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Illustration of lungs on blue silhouette of upper chest on black background
Exploring Pediatric Diffuse Alveolar Hemorrhage: Causes and Outcomes
Exploring Pediatric Diffuse Alveolar Hemorrhage: Causes and Outcomes 1024 575 Erin Gregory

In a groundbreaking study published in Pediatric Pulmonology, Sarah P. Cohen, MD, MS, and Katelyn Krivchenia, MD — both from Nationwide Children’s Hospital — along with their team investigate diffuse alveolar hemorrhage (DAH) in children, a rare but life-threatening condition involving bleeding into the lungs.…

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Challenges in Clinical Decision-Making for Patients with Spinal Muscular Atrophy
Challenges in Clinical Decision-Making for Patients with Spinal Muscular Atrophy 1024 683 Mary Bates, PhD

There are three approved genetic therapies for SMA, but little guidance in treatment selection. Spinal muscular atrophy (SMA) was once a leading cause of inherited infant death in the United States. Today, there are three genetic therapies approved by the Food and Drug Administration…

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