Biofilms: The Good, the Bad & the Groundbreaking

Learn More

Approaching Uncertainty in Medicine With a Growth Mindset

Read More

From Scan to Plan: Making Virtual Surgical Planning the Standard of Care for Ortho-oncology Operations

Find Out More

Lessons Learned: From First Gen Student to Chief Scientific Officer

Read Now

Empowering Therapists With Better Tools

Learn How
Close
Enter your
text here
Bridging the Fertility Awareness Gap in Adolescents With PCOS
 Bridging the Fertility Awareness Gap in Adolescents With PCOS 1024 683 Pam Georgiana
By: Pam Georgiana

Assessing knowledge, concerns and quality of life to inform early clinical counseling While polycystic ovary syndrome (PCOS) is common in adolescent females, little is known about how the potential for long-term complications like infertility affect young patients’ well-being. Research with adult PCOS patients has…

read more
A Novel EEG Evaluation Method for Children With Infantile Spasms
 A Novel EEG Evaluation Method for Children With Infantile Spasms 1024 677 Lauren Dembeck
By: Lauren Dembeck

Clinician-researchers have developed a rapid training program to learn the BASED score, a novel EEG evaluation method. The easily accessible training program allows clinicians to reliably determine the response to treatment. Infantile epileptic spasms syndrome is a severe form of early childhood epilepsy. Onset…

read more
Baby in NICU
The Nurse Perception of Infant Condition (NPIC) Scale: A Tool for NICU Nurses to Evaluate Neonatal Wellbeing
 The Nurse Perception of Infant Condition (NPIC) Scale: A Tool for NICU Nurses to Evaluate Neonatal Wellbeing 1024 683 Jessica Nye, PhD
By: Jessica Nye, PhD

Investigators from Nationwide Children’s Hospital developed a tool for nurses to use when assessing a neonate’s wellbeing, called the Nurse Perception of Infant Condition (NPIC) Scale. “For neonates, it was hard to find a scale that was relevant and would allow us to measure…

read more
Establishing Meaningful Clinical Outcome Measures for Gastrointestinal Symptoms in Cystic Fibrosis
 Establishing Meaningful Clinical Outcome Measures for Gastrointestinal Symptoms in Cystic Fibrosis 1024 683 Lauren Dembeck
By: Lauren Dembeck

Understanding the minimal clinically important differences of PROMs is crucial in interpreting results in clinical trials. Patient-reported outcome measures (PROMs) are a set of standardized questions that directly assess the patient’s perspective of their symptoms and quality of life to better understand their experience…

read more
Black Youth Experience Disparities in Care for First-Episode Psychosis in Ohio
 Black Youth Experience Disparities in Care for First-Episode Psychosis in Ohio 1024 683 Jessica Nye, PhD
By: Jessica Nye, PhD

Black youth enrolled in Medicaid were more likely to experience a first-episode psychosis (FEP) event and be diagnosed with schizophrenia spectrum disorder but less likely to receive key early intervention services than White youth.   “It’s been known for a long time, especially in…

read more
Close up color photo of little boy holding hands on his belly
Childhood-Onset Rumination Syndrome: Insights from 15 Years of Research
 Childhood-Onset Rumination Syndrome: Insights from 15 Years of Research 1024 680 Pam Georgiana
By: Pam Georgiana

Education is needed to improve diagnostic timelines and treatment outcomes for pediatric patients. Childhood-onset rumination syndrome presents significant diagnostic challenges, even for gastroenterologists. Physicians often misdiagnose the symptoms as gastroesophageal reflux disease. Initial treatments frequently fail, leading to delays in accurate diagnosis. Patients can…

read more
Illustration of lungs on blue silhouette of upper chest on black background
Exploring Pediatric Diffuse Alveolar Hemorrhage: Causes and Outcomes
 Exploring Pediatric Diffuse Alveolar Hemorrhage: Causes and Outcomes 1024 575 Erin Gregory
By: Erin Gregory

In a groundbreaking study published in Pediatric Pulmonology, Sarah P. Cohen, MD, MS, and Katelyn Krivchenia, MD — both from Nationwide Children’s Hospital — along with their team investigate diffuse alveolar hemorrhage (DAH) in children, a rare but life-threatening condition involving bleeding into the lungs.…

read more
Challenges in Clinical Decision-Making for Patients with Spinal Muscular Atrophy
 Challenges in Clinical Decision-Making for Patients with Spinal Muscular Atrophy 1024 683 Mary Bates, PhD
By: Mary Bates, PhD

There are three approved genetic therapies for SMA, but little guidance in treatment selection. Spinal muscular atrophy (SMA) was once a leading cause of inherited infant death in the United States. Today, there are three genetic therapies approved by the Food and Drug Administration…

read more
Making the Case for Interdisciplinary BPD Care
 Making the Case for Interdisciplinary BPD Care 150 150 Abbie Miller
By: Abbie Miller

A new review highlights benefits of interdisciplinary BPD management and offers advice on how program development. Bronchopulmonary dysplasia (BPD) affects more than 40% of preterm infants and is the most common lung disease in infancy. There are long term consequences and comorbidities associated with…

read more
Color image of young boy asleep in bed
Pediatric Obstructive Sleep Apnea Diagnosis and Treatment: What You Need to Know
 Pediatric Obstructive Sleep Apnea Diagnosis and Treatment: What You Need to Know 1024 575 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

Pediatric obstructive sleep apnea, a common condition in children, is definitively diagnosed with sleep studies and can be treated through various modalities, depending on disease severity. Obstructive sleep apnea (OSA) is a disorder characterized by snoring, gas exchange abnormalities and disrupted sleep, with near-complete…

read more
How Does Cannabis Use During Pregnancy Affect Children?
 How Does Cannabis Use During Pregnancy Affect Children? 1024 683 Katelyn Scott
By: Katelyn Scott

A recent study shows that prenatal exposure to cannabis is associated with poorer thinking skills and behaviors.  In a study published in JAMA Pediatrics, researchers found prenatal cannabis exposure was associated in early childhood with poorer thinking skills and behaviors such as impulse control,…

read more
The Current and Future State of Scoliosis Care and Research
 The Current and Future State of Scoliosis Care and Research 1024 683 Madison Storm
By: Madison Storm

In the United States alone, scoliosis affects an estimated 7 million people – just under twice the population of Los Angeles – according to the Scoliosis Research Society. Each year, an estimated 30,000 children begin wearing braces for treatment.  Over time, the treatments available…

read more
Advancing Care for Infants with Hypoplastic Left Heart Syndrome: New Insights into Maternal and Community Health Factors
 Advancing Care for Infants with Hypoplastic Left Heart Syndrome: New Insights into Maternal and Community Health Factors 1024 537 Pam Georgiana
By: Pam Georgiana

Nationwide Children’s Heart Center explores the impact of maternal and social determinants of health on congenital heart disease. While maternal-fetal environment factors are known to impact outcomes in babies who receive the traditional Norwood surgery to treat hypoplastic left heart syndrome (HLHS), there is…

read more
1 Trillion Cells: Nationwide Children’s Reaches New Milestone for Universal-Donor NK Cell Studies
 1 Trillion Cells: Nationwide Children’s Reaches New Milestone for Universal-Donor NK Cell Studies 1024 649 Abbie Miller
By: Abbie Miller

The Biologics Manufacturing Resource, Nationwide Children’s Cell and Tissue cGMP manufacturing facility, recently achieved a major milestone. The resource has now delivered more than 1 trillion universal donor natural killer (NK) cells to patients. These NK cells are being studied in clinical trials to…

read more
Subclinical Herpes Simplex Virus in Neonates: What to Do?
 Subclinical Herpes Simplex Virus in Neonates: What to Do? 1024 683 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Neonates can test positive for HSV without having visible lesions or other classic symptoms, leaving clinical uncertainty regarding appropriate antiviral treatment and testing protocols. Researchers at Nationwide Children’s Hospital have shared data on a sample of 17 neonates who tested positive for herpes simplex…

read more
Featured Researcher – Ruoning Wang, PhD
 Featured Researcher – Ruoning Wang, PhD 150 150 Alaina Doklovic
By: Alaina Doklovic

Ruoning Wang, PhD, is a principal investigator in the Center for Childhood Cancer for the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital, a principal investigator for the Division of Hematology and Oncology at Nationwide Children’s Hospital and a professor in the Department…

read more
What Is Insulin’s Role in Diabetes-Related Urinary Tract Infections?
 What Is Insulin’s Role in Diabetes-Related Urinary Tract Infections? 1024 575 Pam Georgiana
By: Pam Georgiana

Two studies reveal how impaired insulin receptors compromise immunity in people with diabetes. While excess glucose in the urine is often thought to be the main factor behind urinary tract infections in people with diabetes, two recent studies led by Laura L. Schwartz, PhD,…

read more
Selective Dorsal Rhizotomy for Cerebral Palsy: Significant Gains in Mobility and Reduction in Spasticity Treatments
 Selective Dorsal Rhizotomy for Cerebral Palsy: Significant Gains in Mobility and Reduction in Spasticity Treatments 928 1024 Erin Gregory
By: Erin Gregory

Recent research shows that selective dorsal rhizotomy (SDR) significantly boosts motor function in children with cerebral palsy (CP), particularly those who are ambulatory. The study highlights motor improvements and a reduced need for spasticity treatments, emphasizing SDR’s potential to enhance outcomes and quality of…

read more
Identifying Ancestry-Based Predictors of Survival in Black Patients with Acute Myeloid Leukemia
 Identifying Ancestry-Based Predictors of Survival in Black Patients with Acute Myeloid Leukemia 1024 768 Alaina Doklovic
By: Alaina Doklovic

Researchers use multiomic profiling to understand ancestry-specific aspects of cancer onset and outcomes. In a recent study, published in ­­­Nature Genetics, researchers from Nationwide Children’s Hospital and The Ohio State University Comprehensive Cancer Center (OSUCCC – James) compared genomic profiles of patients diagnosed with…

read more
Heart with HLHS compared to typically developed heart
Researchers Identify Potential Prenatal Biomarkers of Congenital Heart Diseases
 Researchers Identify Potential Prenatal Biomarkers of Congenital Heart Diseases 1024 637 Katelyn Scott
By: Katelyn Scott

In a research letter published in Circulation Research, researchers at Nationwide Children’s describe a potential biomarker that would identify the presence of SVHD in a fetus based on a maternal blood test. Single ventricle heart diseases (SVHDs), the most severe type of congenital heart…

read more