Better Asthma Outcomes: A Systems-Level Approach

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Universal Donor CAR NK Cells: A New Platform Technology for Cancer

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How Medical-Legal Partnerships Support Families, Relieve Stress and Improve Health

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Finding the Unexpected: Pulmonary Sclerosing Pneumocytoma in a Pediatric Patient
 Finding the Unexpected: Pulmonary Sclerosing Pneumocytoma in a Pediatric Patient 1024 575 Pam Georgiana
By: Pam Georgiana

A case study demonstrates the need for a structured evaluation and consideration of genetic risk factors in rare pediatric tumors. Primary lung tumors in children are rare and present diagnostic uncertainty. A recent case study published in Pediatric Pulmonology highlights the evaluation and management…

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Genome Database Analysis Suggests Cystic Fibrosis is More Globally Distributed Than Previously Believed
 Genome Database Analysis Suggests Cystic Fibrosis is More Globally Distributed Than Previously Believed 1024 768 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Despite lower CF incidence in non-European populations, total CF births in Asia, Africa and South America likely equal or surpass those in North America and Europe. Cystic fibrosis (CF) has long been viewed as a disease that primarily affects people of European descent. Even…

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In Sight: Targeted Muscle Reinnervation
 In Sight: Targeted Muscle Reinnervation 150 150 Abbie Miller
By: Abbie Miller

Amputation in pediatrics is often a result of traumatic injury or cancers, such as osteosarcoma. At Nationwide Children’s, Thomas Scharschmidt, MD, director of the Orthopedic Oncology Program, is a leader in limb salvage surgery and targeted muscle reinnervation.  Targeted muscle reinnervation (TMR) is a…

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Dr. Joan Han standing in a white coat in a hospital setting
Hot Topics in Endocrinology: A conversation with Joan Han, MD, Division Chief of Endocrinology at Nationwide Children’s
 Hot Topics in Endocrinology: A conversation with Joan Han, MD, Division Chief of Endocrinology at Nationwide Children’s 1024 605 Pam Georgiana
By: Pam Georgiana

Joan C. Han, MD, became chief of the Division of Endocrinology at Nationwide Children’s Hospital in January 2026. She is a nationally recognized physician-scientist in pediatric obesity and metabolic disease. In this Q&A, Dr. Han discusses the most pressing issues in pediatric endocrinology and…

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The Growing Use of Robotics in General Pediatric Surgical Procedures
 The Growing Use of Robotics in General Pediatric Surgical Procedures 1024 683 Lauren Dembeck
By: Lauren Dembeck

Pediatric surgeons are increasingly turning to robotic technology for the delivery of safe and enhanced minimally invasive surgical approaches for younger children. Over the past two decades, the use of minimally invasive surgery (MIS) techniques for both laparoscopic and thoracoscopic surgery have been widely…

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Q&A With Cory Criss, MD: Advancing Pediatric Care Through Innovation
 Q&A With Cory Criss, MD: Advancing Pediatric Care Through Innovation 150 150 Alaina Doklovic
By: Alaina Doklovic

Cory Criss, MD, is a pediatric surgeon at Nationwide Children’s Hospital and the founder and director of the Innovation Center. He also serves as the chief operating officer and co-principal investigator of the Midwest Pediatric Device Consortium (MPDC), a multi-million-dollar FDA funded initiative accelerating…

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Portrait of Alexander Bishop, DPhil, standing in a hospital lobby and smiling, wearing a navy blazer and light blue shirt.
From Biology to Bedside: How the Center for Childhood Cancer Research Is Shaping What Comes Next
 From Biology to Bedside: How the Center for Childhood Cancer Research Is Shaping What Comes Next 1024 627 Madison Storm
By: Madison Storm

An interview with Alexander Bishop, DPhil, director of the Center for Childhood Cancer Research, principal investigator and Richard J. Solove Endowed Chair in Cancer Clinical Developmental Therapeutics at Nationwide Children’s Hospital. At Nationwide Children’s Hospital, the mission of the Center for Childhood Cancer Research…

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Illustration of a heart showing the Fontan surgery
Tissue Engineered Vascular Grafts: A Breakthrough for Children With Heart Defects
 Tissue Engineered Vascular Grafts: A Breakthrough for Children With Heart Defects 968 1024 Abbie Miller
By: Abbie Miller

An innovation 30 years in the making is poised to change the way children with single ventricle disease experience life after a Fontan procedure. Children with single ventricle disease are often described as having “half a heart.” What this really means is that one…

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DNA Methylation-Based Diagnostics: Refining Diagnosis for the Most Complex Pediatric Brain Tumors
 DNA Methylation-Based Diagnostics: Refining Diagnosis for the Most Complex Pediatric Brain Tumors 1024 783 Lauren Dembeck
By: Lauren Dembeck

Developed at Nationwide Children’s, the MACDADI classifier is compatible with next-generation methylation arrays and quickly delivers more accurate tumor diagnoses, offering a clinically validated alternative to outdated and unregulated methylation classifiers. Diagnosing central nervous system (CNS) tumors in children is among the most challenging…

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Dr. Zarife Sahenk, MD, PhD
One Gene, Big Impact: The Science Behind a New Therapy for Brain and Muscle Health
 One Gene, Big Impact: The Science Behind a New Therapy for Brain and Muscle Health 1024 683 Madison Storm
By: Madison Storm

A promising new gene therapy developed at Nationwide Children’s Hospital is offering hope for new patients with neurodegenerative and muscle disorders. Led by Zarife Sahenk, MD, PhD, a neurologist, principal investigator in the Jerry R. Mendell Center for Gene Therapy and director of Clinical…

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Startups Update: Where Are They Now?
 Startups Update: Where Are They Now? 1024 683 Madison Storm
By: Madison Storm

From cutting-edge gene therapies to transformative medical devices, startups are redefining what’s possible in-patient care and technology. Born from pioneering research and nurtured through strategic collaborations, startups are tackling critical challenges—from neonatal care to oncology and rare genetic disorders—while advancing toward commercialization. Supported by…

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Newborn baby with nasal canula oxygen support receiving care in a neonatal intensive care unit (NICU) at a hospital, resting while monitored by medical staff.
Shorter Antibiotic Courses Appear Safe for Uncomplicated Gram-Negative Bloodstream Infections in the NICU
 Shorter Antibiotic Courses Appear Safe for Uncomplicated Gram-Negative Bloodstream Infections in the NICU 1024 602 Pam Georgiana
By: Pam Georgiana

Neonatology and pediatric pharmacy partner to advance antibiotic stewardship. For years, Pablo J. Sánchez, MD, principal investigator in the Center for Perinatal Research in the Abigail Wexner Research Institute at Nationwide Children’s Hospital, observed that approximately 7 days of antibiotic therapy appeared sufficient for…

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Eric Youngstrom, PhD
Norms, Needs and New Frontiers in Pediatric Mental Health
 Norms, Needs and New Frontiers in Pediatric Mental Health 1024 683 Madison Storm
By: Madison Storm

 An interview with Eric Youngstrom, PhD, director of the Institute for Mental and Behavioral Health Research at the Abigail Wexner Research Institute at Nationwide Children’s Hospital. At Nationwide Children’s Hospital, the Institute for Mental and Behavioral Health Research (IMBHR) is driving discovery through improved…

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Understanding the Rising Suicide Risk Among Black Youth
 Understanding the Rising Suicide Risk Among Black Youth 1024 576 Alaina Doklovic
By: Alaina Doklovic

A new large-scale Medicaid study sheds light on complex factors driving risk and the protective factors that may help save lives. Suicide rates among Black youth (children, adolescents and young adults) have risen sharply in recent years, surpassing those of other racial and ethnic…

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Featured Researcher: Brian Becknell, MD, PhD
 Featured Researcher: Brian Becknell, MD, PhD 150 150 Gina Vitale, PTA
By: Gina Vitale, PTA

Urinary tract infections (UTIs) are among the most common bacterial infections in children worldwide, according to the Journal of Pediatric Urology. Did you know that UTIs can be associated with congenital anomalies, which may cause permanent renal scarring in certain children, resulting in long-term…

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Registry Data Provide Insight Into Ultra-Rare Pediatric Tenosynovial Giant Cell Tumors
 Registry Data Provide Insight Into Ultra-Rare Pediatric Tenosynovial Giant Cell Tumors 1024 473 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

At A Glance Tenosynovial giant cell tumor (TGCT) is a rare condition that affects joints, mostly in adults but sometimes in children. New research using an international patient registry shows that children often wait more than a year for the correct diagnosis because symptoms…

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Blood Sample in test tube
Filling a Critical Gap in Relapsed Sarcoma Treatment
 Filling a Critical Gap in Relapsed Sarcoma Treatment 1024 683 Pam Georgiana
By: Pam Georgiana

A first-in-sarcoma trial at Nationwide Children’s Hospital tests universal-donor NK cells with chemotherapy to address poor survival rates.   The five-year overall survival rate for children and young adults with relapsed bone or soft tissue sarcomas is between 17 and 26%. For Bhuvana A. Setty, MD, pediatric hematologist…

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Baby Bryson laughing at a check up following treatment for SMA.
Nationwide Children’s Hospital Completes One of the World’s First Prenatal Treatments for Spinal Muscular Atrophy
 Nationwide Children’s Hospital Completes One of the World’s First Prenatal Treatments for Spinal Muscular Atrophy 1024 600 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Investigational third-trimester, transplacental “bridging” therapy with risdiplam — followed by rapid postnatal treatment — aims to protect motor neurons during a critical window before and immediately after birth.  When Stacy Auker found out she was pregnant with her third child, she knew a diagnosis of spinal muscular atrophy (SMA) was…

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Selective Steroid Use After Kasai Portoenterostomy Improves Outcomes in Biliary Atresia
 Selective Steroid Use After Kasai Portoenterostomy Improves Outcomes in Biliary Atresia 1024 683 Pam Georgiana
By: Pam Georgiana

Postoperative protocol is associated with improved bile drainage and higher native liver survival without increased short-term risk. A new study published in the Journal of Pediatric Gastroenterology and Nutrition provides evidence that a selective, marker-guided approach to postoperative steroid use improves outcomes for infants…

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Study Shows Younger Children Experience Persistent Symptoms Following Concussion
 Study Shows Younger Children Experience Persistent Symptoms Following Concussion 1024 540 Abbie Miller and Katelyn Scott
By: Abbie Miller and Katelyn Scott

Nearly 30% of children younger than 6 years who had a concussion during the study had prolonged symptoms, which can affect learning and behavior later in childhood. When people typically think of concussion, the first type of patient that comes to mind is a…

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