Better Asthma Outcomes: A Systems-Level Approach

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Universal Donor CAR NK Cells: A New Platform Technology for Cancer

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How Medical-Legal Partnerships Support Families, Relieve Stress and Improve Health

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Cultivating Culture in a High-Growth, High-Performance Organization

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Nationwide Children’s Team Builds Award-Winning AI Tool to Drive Mental Health Research
 Nationwide Children’s Team Builds Award-Winning AI Tool to Drive Mental Health Research 1024 502 Abbie Miller
By: Abbie Miller

DREAM project wins the 2025 Gartner Eye on Innovation Mid-Size Enterprise Award in the Americas region. In recognition of its innovative application of technology to address critical health care challenges, the Office of Data Sciences was selected as the winner for the prestigious 2025…

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Color image of enteral complete liquid nutritional products of several brands
Food-Based Tube Feeding: Balancing Parental Demand With Pediatric Nutrition Science
 Food-Based Tube Feeding: Balancing Parental Demand With Pediatric Nutrition Science 1024 575 Pam Georgiana
By: Pam Georgiana

New research from Nationwide Children’s reveals significant differences in nutrient adequacy across commercial food-based formulas. In the last two decades, enteral nutrition has undergone a significant transformation. Fifteen to 20 years ago, pediatric patients requiring gastrostomy tube feeding had only one option: synthetic, cow…

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Guiding the Treatment of Ballistic Fractures: A New Report Offers Education and Support for Orthopedic Surgeons
 Guiding the Treatment of Ballistic Fractures: A New Report Offers Education and Support for Orthopedic Surgeons 1024 657 Alaina Doklovic
By: Alaina Doklovic

Despite firearm injury incidence and severity in children, no guidelines for orthopedic surgeons existed – until now. Firearm-related injury is the leading cause of death in the United States among children and adolescents aged 1 to 19. Despite this alarming statistic, there were no…

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Parents’ Perceptions Highlight Gaps in Supporting Children with Epilepsy in School
 Parents’ Perceptions Highlight Gaps in Supporting Children with Epilepsy in School 1024 579 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

Discussions with parents of children with epilepsy revealed concerning gaps in school-based seizure education and care, underscoring the need for better lines of communication between medical teams, school personnel, and the children’s families.   A qualitative study led by Mary Kay Irwin, EdD, and…

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Closing the Treatment Gap: Opioid Use Disorder Medications in Adolescents and Young Adults
 Closing the Treatment Gap: Opioid Use Disorder Medications in Adolescents and Young Adults 1024 683 Pam Georgiana
By: Pam Georgiana

Findings from the PROUD trial highlight the need for youth-centered prescription strategies in primary care. Adolescents and young adults are far less likely than older adults to receive evidence-based medications for opioid use disorder (OUD), even though buprenorphine and extended-release naltrexone are recommended treatments.…

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Advances in the Care of Patients With Chest Wall Deformities
 Advances in the Care of Patients With Chest Wall Deformities 1024 683 Sara Mansfield, MD
By: Sara Mansfield, MD

Every year Nationwide Children’s Hospital sees several hundred children and adolescents with chest wall deformities. Common Chest Wall Conditions Two of the most common chest wall diagnoses are pectus excavatum (sunken chest) and pectus carinatum (pigeon chest).  These conditions can cause a variety of…

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LaCrosse Virus: What You Need to Know
 LaCrosse Virus: What You Need to Know 1024 586 Christopher Ouellette, MD
By: Christopher Ouellette, MD

La Crosse virus (LACV) is a mosquito-borne illness primarily found in the upper Midwest, Mid-Atlantic, and southeastern United States. This virus is spread mostly through the bite of the eastern treehole mosquito, Aedes triseriatus, and over the past 20+ years, more cases have been…

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Virtual Reality Training Model Aims to Transform Workplace Safety in Health Care
 Virtual Reality Training Model Aims to Transform Workplace Safety in Health Care 1024 683 Madison Storm
By: Madison Storm

A virtual reality (VR) training module developed at Nationwide Children’s Hospital, called DEFUSE, which stands for De-escalate Effectively, Foster Understanding, Safeguard Environments, is setting a new standard for workplace violence prevention in health care settings. Funded by the Ohio Bureau of Workers’ Compensation, the…

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Post-Ictal Rhythmic Thalamic Activity in the Central Media Nucleus May Play a Role in Seizure Termination in Drug-Resistant Epilepsy
 Post-Ictal Rhythmic Thalamic Activity in the Central Media Nucleus May Play a Role in Seizure Termination in Drug-Resistant Epilepsy 1024 677 Jessica Nye, PhD
By: Jessica Nye, PhD

Investigators from Nationwide Children’s Hospital are the first to describe post-ictal rhythmic thalamic activity (PIRTA) in the central media nucleus (CMN) during focal onset seizure. “When this paper was published, it was a period where understanding the role of the center of the thalamus…

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Device for monitoring glucose placed on girl's arm
Choosing a Continuous Glucose Monitor After TPIAT: When Research Directly Impacts Clinical Practice
 Choosing a Continuous Glucose Monitor After TPIAT: When Research Directly Impacts Clinical Practice 1024 683 Pam Georgiana
By: Pam Georgiana

Nationwide Children’s study highlights hydroxyurea interference with Dexcom, but not with Libre, and the clinical implications for glycemic management. Total pancreatectomy with islet autotransplantation (TPIAT) is the definitive surgical treatment for acute recurrent and chronic pancreatitis. Nationwide Children’s Hospital is one of the very…

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Advancing Pediatric Behavioral Health: Care, Research and Prevention
 Advancing Pediatric Behavioral Health: Care, Research and Prevention 150 150 Nationwide Children's
By: Nationwide Children's

Meet David Axelson, MD, Chief of Psychiatry and Behavioral Health Dr. Axelson and his team have achieved amazing things in the last decade, from more than doubling the volume of patients served to establishing a new research institute for mental and behavioral health, and…

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Norms, Needs and New Frontiers in Pediatric Mental Health
 Norms, Needs and New Frontiers in Pediatric Mental Health 1024 683 Madison Storm
By: Madison Storm

An interview with Eric Youngstrom, PhD, director of the Institute for Mental and Behavioral Health Research at the Abigail Wexner Research Institute at Nationwide Children’s Hospital.   At Nationwide Children’s Hospital, the Institute for Mental and Behavioral Research (IMBHR) is driving discovery through improved…

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How Useful Are Large Language Models for Caregivers of Pediatric Cancer Patients?
 How Useful Are Large Language Models for Caregivers of Pediatric Cancer Patients? 1024 502 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

These powerful informational tools for caregivers of pediatric cancer patients vary in areas such as readability and source credibility, highlighting the need to carefully consider their clinical utility. A recent study led by Emre Sezgin, PhD, and Micah Skeens, PhD, APRN, FAAN, CPNP-PC, at…

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Smiling child wearing a blue bike helmet and vest while riding outdoors on a sunny day, promoting bicycle safety and healthy outdoor activities for kids.
Better Asthma Outcomes: A Systems-Level Approach
 Better Asthma Outcomes: A Systems-Level Approach 1024 422 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

A dedicated team of experts embraced sweeping tactics to reduce asthma-related emergency department visits by 33% and inpatient length of stay by 0.9 days. This is how they did it. It started with a conversation about the data: Why are kids with asthma the…

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Close-up of newly designed IV line clamps that improve patient safety and usability in hospitals by providing secure, easy-to-adjust flow control for intravenous therapy.
Enhanced IV Line Clamp: A New Spin on a Classic
 Enhanced IV Line Clamp: A New Spin on a Classic 1024 683 Madison Storm
By: Madison Storm

Revolutionizing patient care through human-centered design The IV line clamp is a long-standing technology used to deliver intravenous medications and fluids. For over 90 years, the simplistic, gravity-based design has remained unchanged, despite the growing complexity of patient care and significant advancements in medical…

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How Medical-Legal Partnerships Support Families, Relieve Stress and Improve Health
 How Medical-Legal Partnerships Support Families, Relieve Stress and Improve Health 1024 320 Wendy Margolin
By: Wendy Margolin

With a small team of dedicated attorneys working as part of a medical-legal partnership, Lawyers for Kids is making an outsized impact for families at Nationwide Children’s Hospital. A classic example of a medical-legal partnership case is a child with asthma who frequently visits…

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A Digital Bundle to Help Primary Care Clinicians Successfully Promote Cardiovascular Health
 A Digital Bundle to Help Primary Care Clinicians Successfully Promote Cardiovascular Health 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

A web-based app that integrates into electronic record systems could offer primary care providers an evidence-based way to effectively address cardiovascular risks and behavior change with parents. On average, physicians get a total of 4 hours of education in nutrition and behavior change counseling…

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Bridging Care and Curiosity: Mentoring the Physician-Scientists of Tomorrow
 Bridging Care and Curiosity: Mentoring the Physician-Scientists of Tomorrow 1024 316 Alaina Doklovic
By: Alaina Doklovic

The resident Research Pathway at Nationwide Children’s uniquely prepares trainees for medical research. Physician-scientists play a key role in bridging scientific discoveries and clinical care. That’s why Nationwide Children’s Hospital is committed to leading the path for the healers and innovators of tomorrow. The…

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Catherine Krawczeski, MD
Cultivating Culture in a High-Growth, High-Performance Organization
 Cultivating Culture in a High-Growth, High-Performance Organization 700 407 Catherine Krawczeski, MD
By: Catherine Krawczeski, MD

Catherine Krawczeski, MD, chief medical officer and physician-in-chief at Nationwide Children’s shares her thoughts on how to drive a positive, collaborative culture while pursuing academic and clinical excellence. When you walk through the doors of Nationwide Children’s Hospital, you can feel it: the energy,…

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Making Universal Donor CAR NK Cells
 Making Universal Donor CAR NK Cells 1024 320 Abbie Miller
By: Abbie Miller

This article appeared in the 2025 Fall/Winter print issue. Download the issue here.   Image credit: Nationwide Children’s Read the Full Article: Universal Donor CAR NK Cells: A New Platform Technology for Cancer About the authorAuthorArticles by the Author Abbie MillerAbbie (Roth) Miller, MS, MWC,…

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