Biofilms: The Good, the Bad & the Groundbreaking

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Approaching Uncertainty in Medicine With a Growth Mindset

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From Scan to Plan: Making Virtual Surgical Planning the Standard of Care for Ortho-oncology Operations

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Lessons Learned: From First Gen Student to Chief Scientific Officer

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Empowering Therapists With Better Tools

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Biofilms: The Good, the Bad & the Groundbreaking
 Biofilms: The Good, the Bad & the Groundbreaking 1024 615 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Decades of research into the structure and function of bacterial biofilms have begun to pay off in the form of imminent clinical applications capable of harnessing both the protective and problematic aspects of this universal phenomenon. Imagine a hospital emergency department filled with patients…

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Delivering Implicit Bias Training for Health Care Providers – Via Smartphone
 Delivering Implicit Bias Training for Health Care Providers – Via Smartphone 1024 680 Jessica Nye, PhD
By: Jessica Nye, PhD

A Virtual and Augmented Reality Implicit Association Training (VARIAT) app developed by investigators from Nationwide Children’s Hospital and The Ohio State University leverages mobile technology to bring implicit bias training to the hands of Medicaid clinicians. Everyone has implicit biases that manifest as favorable…

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From Scan to Plan: Making Virtual Surgical Planning the Standard of Care for Ortho-oncology Operations
 From Scan to Plan: Making Virtual Surgical Planning the Standard of Care for Ortho-oncology Operations 1024 281 Abbie Miller
By: Abbie Miller

“We deal in rarities,” says Thomas Scharschmidt, MD, director of the Pediatric Orthopedic Oncology Program at Nationwide Children’s Hospital and professor of Orthopedics at The Ohio State University. “When you consider that across the entire U.S. population, we have between 2,500 and 3,000 cases…

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Lessons Learned: From First Gen Student to Chief Scientific Officer
 Lessons Learned: From First Gen Student to Chief Scientific Officer 1024 683 Nationwide Children's
By: Nationwide Children's

Joanne Turner, PhD, chief scientific officer at the Abigail Wexner Research Institute at Nationwide Children’s Hospital, shares what it’s like to go from first gen college student to academic leadership.    What inspired you to go to college and pursue a bachelor’s degree in…

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Empowering Therapists With Better Tools
 Empowering Therapists With Better Tools 1024 481 Wendy Margolin
By: Wendy Margolin

New research director sets out to improve mental and behavioral health care with assessments.  Providing mental or behavioral health care without simple, effective clinical assessment tools is like trying to lose weight without access to a bathroom scale, says Eric Youngstrom, PhD, the new…

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How Do Treatments for Adolescent Obesity Compare?
 How Do Treatments for Adolescent Obesity Compare? 1024 682 Pam Georgiana
By: Pam Georgiana

A recent review of the literature highlights current treatment strategies for adolescent obesity. According to the American Academy of Pediatrics (AAP), obesity and severe obesity are chronic health conditions with increasing incidence in adolescents, putting them at risk for associated comorbidities. Obesity affects approximately…

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Advancing Predictive Models in Pediatric Traumatic Brain Injury
 Advancing Predictive Models in Pediatric Traumatic Brain Injury 1024 683 Erin Gregory
By: Erin Gregory

Traumatic brain injury (TBI) is the leading cause of disability and mortality among children, causing thousands of deaths each year. Despite tools such as the Glasgow Outcomes Scale (GOS) and the Pediatric Glasgow Coma Scale (PGCS), reliable methods for predicting mortality during initial trauma…

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Loss of RNase 6 Increases Susceptibility to Upper Urinary Tract Infections, Model Shows
 Loss of RNase 6 Increases Susceptibility to Upper Urinary Tract Infections, Model Shows 1024 575 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

The latest in a robust series of studies confirms an important role for RNase 6 in deterring infections of the ureters and kidneys.   Research teams at the Abigail Wexner Research Institute at Nationwide Children’s Hospital have long been studying a superfamily of ribonucleases…

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Do Text Messages Help Youth at Risk For Suicide Feel Supported After Discharge?
 Do Text Messages Help Youth at Risk For Suicide Feel Supported After Discharge? 1024 683 Katelyn Scott
By: Katelyn Scott

Nationwide Children’s is the first pediatric hospital to implement Caring Contacts approach within its Zero Suicide initiative. The initial study period shows high enrollment and satisfaction with the program. Youth who receive care for suicidal thoughts and behaviors need extra support as they transition…

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Surgical Repair of Cloacal Malformation Does Not Worsen Bladder Function
 Surgical Repair of Cloacal Malformation Does Not Worsen Bladder Function 1024 683 Mary Bates, PhD
By: Mary Bates, PhD

The complexity of the malformation, more than the surgical approach, determines post-operative urodynamics. Approximately 90% of girls with cloacal malformation exhibit some degree of bladder dysfunction. While associated conditions can impact bladder dynamics, the complex surgery required to repair cloacal malformation has also been…

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Has the Next Generation of Gene Therapy Arrived?
 Has the Next Generation of Gene Therapy Arrived? 1024 683 Wendy Margolin
By: Wendy Margolin

Researchers crack the code to deliver dual gene therapy in preclinical studies – with promises of wider applications. In a gene therapy breakthrough, a Nationwide Children’s Hospital researcher has successfully used an adeno-associated virus (AAV) to introduce two genes into cells with a single…

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Uncovering the Alarming Rise in Death by Suicide Among Preteens
 Uncovering the Alarming Rise in Death by Suicide Among Preteens 1024 657 Pam Georgiana
By: Pam Georgiana

Data from a new study implies that gender and race/ethnicity play a role in increasing suicide rates. Youth suicide is a significant public health concern. When the National Institute of Mental Health convened a research roundtable series to address the rising rates of death…

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Enhancing School Readiness for Children with Critical Congenital Heart Disease: Insights and Strategies for Health Care Clinicians
 Enhancing School Readiness for Children with Critical Congenital Heart Disease: Insights and Strategies for Health Care Clinicians 1024 664 Erin Gregory
By: Erin Gregory

A recent publication in Pediatric Cardiology explores the complexities of school readiness among children with critical congenital heart disease (CCHD) compared to their peers. The study hypothesizes that children with CCHD will face more significant difficulties in school readiness, linked to specific medical risk factors associated…

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Sacral Nerve Stimulation Improves Symptoms and Quality of Life in Children With Defecation Disorders
 Sacral Nerve Stimulation Improves Symptoms and Quality of Life in Children With Defecation Disorders 1024 656 Mary Bates, PhD
By: Mary Bates, PhD

A new study narrows down the patients who may benefit the most from the treatment. In a large prospective study, researchers from Nationwide Children’s Hospital found that sacral nerve stimulation can lead to significant and long-lasting improvements in fecal continence and quality of life…

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Can Artificial Intelligence (AI) Improve Access to Social Resources for Better Patient Outcomes?
 Can Artificial Intelligence (AI) Improve Access to Social Resources for Better Patient Outcomes? 1024 540 Pam Georgiana
By: Pam Georgiana

A recent study tests the ability of the DAPHNE© Chatbot to do just that. Health care providers and organizations recognize the impact of social factors on health and are increasingly addressing social determinants to improve health outcomes and equity. However, integrating social care into…

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Molly Fuchs, MD
Long-Term Bladder Management and Continence in Girls With Cloacal Malformation
 Long-Term Bladder Management and Continence in Girls With Cloacal Malformation 1024 683 Pam Georgiana
By: Pam Georgiana

New insights on outcomes and quality of life from Nationwide Children’s comprehensive study of pediatric patients. Over the last decade, surgical innovation has revolutionized the treatment of cloacal malformation, a congenital anomaly affecting the development of the gastrointestinal, urinary and reproductive systems in girls.…

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Rethinking Male Bias in Pediatric Growth Hormone Deficiency
 Rethinking Male Bias in Pediatric Growth Hormone Deficiency 1024 683 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

Although males have historically been over-represented in pediatric growth hormone deficiency (GHD) cases, this predominance does not hold true across various classifications of GHD.   Referrals for short-stature evaluations are common in pediatric endocrinology despite the rarity of growth hormone deficiency (GHD). Historically, boys…

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Is Surfactant Treatment at Birth Associated With Severe Bronchopulmonary Dysplasia?
 Is Surfactant Treatment at Birth Associated With Severe Bronchopulmonary Dysplasia? 1024 683 Pam Georgiana
By: Pam Georgiana

An observational study reviews a contemporary cohort of preterm infants. Recently, Leif D. Nelin, MD, division chief of neonatology at Nationwide Children’s and a professor of pediatrics at The Ohio State University College of Medicine, and a team of doctors in the Bronchopulmonary Dysplasia…

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Featured Researcher – Mark Peeples, PhD
 Featured Researcher – Mark Peeples, PhD 150 150 Alaina Doklovic
By: Alaina Doklovic

Mark E. Peeples, PhD, is a principal investigator and member of the Center for Vaccines and Immunity at The Abigail Wexner Research Institute at Nationwide Children’s Hospital, and a professor of Pediatrics and of Molecular & Cellular Biochemistry at The Ohio State University College…

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Water Beads: Sensory Fun or Ticket to the Emergency Department?
 Water Beads: Sensory Fun or Ticket to the Emergency Department? 1024 683 Laura Dattner
By: Laura Dattner

Researchers find ED visits more than doubled from 2021 to 2022 and call for federal legislation and regulation to address this child hazard. Researchers from the Center for Injury Research and Policy and Central Ohio Poison Center at Nationwide Children’s Hospital have found more…

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