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Monthly Archives :

March 2025

Congenital Hypothyroidism: What Endocrinologists Need to Know
 Congenital Hypothyroidism: What Endocrinologists Need to Know 1024 585 Pam Georgiana
By: Pam Georgiana

Your top 10 questions are answered by Nationwide Children’s experts from the Division of Endocrinology. Congenital hypothyroidism (CH) is a common endocrine disorder, affecting approximately 1 in every 2,000 to 4,000 live births globally. Confusion regarding proper screening and follow-up protocols for this serious yet preventable condition impact clinical care and outcomes for children with…

Meet Amy Brown Schlegel, MD, Section Chief of Neonatology
 Meet Amy Brown Schlegel, MD, Section Chief of Neonatology 1024 603 Pam Georgiana
By: Pam Georgiana

After over a decade in Neonatology at Nationwide Children’s Hospital, Dr. Schlegel has been appointed section chief of Neonatology. We recently sat down to talk with Dr. Schlegel about her time at Nationwide Children’s and her plans for leading the next phase of growth in Neonatal care. Amy Brown Schlegel, MD, practices Neonatology in the…

Featured Researcher – Julie Leonard, MD, MPH
 Featured Researcher – Julie Leonard, MD, MPH 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

As a long-time pediatric trauma clinician-scientist, Julie Leonard, MD, MPH, board-certified emergency medicine specialist and principal investigator in the Center for Injury Research and Policy at Nationwide Children’s Hospital, has contributed to numerous veins of research in her field. The recent publication of a set of clinical prediction criteria for cervical spine injury represents the…

After Concussion: Monitor Sleep and Limit Daytime Naps for Faster Recovery
 After Concussion: Monitor Sleep and Limit Daytime Naps for Faster Recovery 1024 540 Laura Dattner
By: Laura Dattner

A new study reinforces the importance of sleep for concussion recovery and supports recommendations for quality nighttime sleep with limited naps. Researchers have found that when it comes to concussion recovery, sleep matters. In a study published in British Journal of Sports Medicine, researchers from Nationwide Children’s Hospital found that limiting daytime sleep and getting…

Eat, Sleep, Console: Reducing NICU Admissions of Infants With Prenatal Opioid Exposure
 Eat, Sleep, Console: Reducing NICU Admissions of Infants With Prenatal Opioid Exposure 1024 575 Lauren Dembeck
By: Lauren Dembeck

Focusing on non-pharmacological care, emphasizing mother-baby bonding, and natural infant behaviors may keep infants out of the NICU, but other barriers may limit implementation. Infants exposed to opioids in utero may experience withdrawal symptoms after birth, which can vary in severity depending on many factors, such as length of exposure and type of opioid. In…

Updated Small Baby Care Guidelines Reflect 20 Years of Work Toward Improved Outcomes
 Updated Small Baby Care Guidelines Reflect 20 Years of Work Toward Improved Outcomes 1024 683 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Thorough management guidelines for babies born before 27 weeks’ gestation join the program’s long list of accomplishments in improving survival and standardizing care for this vulnerable population. As the Small Baby Program at Nationwide Children’s Hospital celebrates its 20th anniversary, it is also releasing its latest set of care guidelines for their tiny patients. Divided…

Breaking New Ground in Cancer Immunotherapy
 Breaking New Ground in Cancer Immunotherapy 1024 683 Pam Georgiana
By: Pam Georgiana

Nationwide Children’s researchers develop a scalable, targeted approach to overcoming cancer’s toughest challenges. Despite significant advances in treatments, cancer remains one of the leading causes of death globally. Traditional therapies, while improving patient outcomes, still have limitations — such as the need for frequent dosing, complex and costly manufacturing and severe side effects. These challenges…

Varhouse and AVA: Revolutionizing Genomic Data Management and Interpretation
 Varhouse and AVA: Revolutionizing Genomic Data Management and Interpretation 1024 672 Lauren Dembeck
By: Lauren Dembeck

The groundbreaking software system is used for both research and clinical purposes and is transforming how genomic data is organized, interpreted and applied to improve patient care. When it comes to working with big data, it doesn’t get much bigger than the human genome. Each of our genomes has approximately 6 billion data points, half…

Leveraging Technology and Partnerships to Transform Pediatric Orthopedic Care
 Leveraging Technology and Partnerships to Transform Pediatric Orthopedic Care 1024 683 Erin Gregory
By: Erin Gregory

An interview with Allen A. Kadado, MD, director of the Nationwide Children’s Hospital Center for Orthopedic Innovation, director of the Nationwide Children’s Pediatric Orthopedic Residency Program At Nationwide Children’s Hospital, the Department of Orthopedics drives pediatric health care innovation through collaborations that bridge clinical expertise and technological advancement. Specializing in areas like spinal deformities, trauma…

More Than One REMEDY for Genetic Disorders
 More Than One REMEDY for Genetic Disorders 1024 768 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

How a new approach to correcting heterozygous mutations and other novel techniques for gene editing are transforming the potential to combat disease The field of gene therapy has had some astounding success in recent years — much of which emerged from labs at Nationwide Children’s Hospital — but it has also stumbled over some serious…

Innovative Highchair Design Revolutionizes Pediatric Care: A Collaborative Journey From Concept to Prototype
 Innovative Highchair Design Revolutionizes Pediatric Care: A Collaborative Journey From Concept to Prototype 1024 683 Madison Storm
By: Madison Storm

Highchairs are common in homes with babies and toddlers, as well as in places such as hospitals and restaurants where young children are fed. In hospitals, they are mainly used in pediatric care for infants, toddlers and children undergoing treatment or recovery. Highchairs provide a safe, stable seating option during meals and interactions with family,…

Why Aren’t Pediatric Kidney Stone Patients Returning for Follow-up After Surgery?
 Why Aren’t Pediatric Kidney Stone Patients Returning for Follow-up After Surgery? 1024 732 Lauren Dembeck
By: Lauren Dembeck

Kidney stones in children are on the rise, and many of these children miss critical post-op follow-ups. What prevents them from returning, and how can we help? Since 2000, kidney stone cases in the U.S. pediatric population have risen by 6–10% annually, leading to a corresponding increase in surgical interventions. Alarmingly, nearly half of pediatric…

What’s New in Pulmonary Care for Children With Sickle Cell Disease?
 What’s New in Pulmonary Care for Children With Sickle Cell Disease? 1024 575 Erin Gregory
By: Erin Gregory
Illustration of lungs on blue silhouette of upper chest on black background

A recent publication reviews the impact of pulmonary complications on children and youth with sickle cell disease (SCD) and offers suggestions to improve outcomes. Pulmonary complications are a leading cause of morbidity and mortality in children with sickle cell disease (SCD), yet they remain underrecognized and undertreated. A recent review published in Clinics in Chest Medicine…

Pivotal New Research Fuels Possibilities for Aggressive Pediatric Brain Cancer
 Pivotal New Research Fuels Possibilities for Aggressive Pediatric Brain Cancer 1024 414 Wendy Margolin
By: Wendy Margolin

A new umbrella trial of molecularly driven therapies for high-grade gliomas (HGG) and diffuse intrinsic pontine glioma (DIPG) aims to improve quality of live and extend survival rates for these aggressive tumors. The diagnosis of high-grade glioma (HGG), a type of aggressive, malignant brain tumor, in pediatric patients is particularly heartbreaking. HGGs are one of…