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Monthly Archives :

December 2022

Supplementation With Omega 3-6 Improves a Marker of Inflammation Among Children Newly Diagnosed With Autism Spectrum Disorder
 Supplementation With Omega 3-6 Improves a Marker of Inflammation Among Children Newly Diagnosed With Autism Spectrum Disorder 1024 681 Jessica Nye, PhD
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Fatty acid supplementation may be a treatment route for addressing some underlying causes of autism spectrum disorder (ASD) among children.   One potential mechanism affecting autism-related behaviors is inflammation. In general, ASD severity has been associated with inflammatory cytokine levels and externalizing behaviors with interleukin (IL)-10 and IL-1β levels. Supplementation may be a treatment route,…

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CFTR Modulation Therapy Improves Markers of Inflammation and Lung Function in Cystic Fibrosis
 CFTR Modulation Therapy Improves Markers of Inflammation and Lung Function in Cystic Fibrosis 1024 575 Jessica Nye, PhD
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Illustration of lungs on blue silhouette of upper chest on black background

Six months of elexacaftor-tezacaftor-ivacaftor (ETI) therapy significantly reduced proinflammatory cytokines, increased immune cell composition, and improved clinical outcomes in cystic fibrosis (CF).   “Cystic fibrosis is a progressive lung disease that carries significant morbidity,” says Shahid Sheikh, MD, of the Pulmonary Medicine and Allergy/Immunology section at Nationwide Children’s Hospital and a professor at The Ohio…

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Predicting Risk of Nosocomial Infection in Pediatric Burn Patients: Can Measures of Adaptive Immune Function Help?
 Predicting Risk of Nosocomial Infection in Pediatric Burn Patients: Can Measures of Adaptive Immune Function Help? 150 150 Abbie Miller
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Pediatric burn injuries affect 1 million children each year in the United States. While burn care improvements have decreased mortality, infection-related complications remain a significant problem. According to the National Burn Repository, four of the top five complications of pediatric burns are infection related. Plus, infection-related complications occur in up to 60% of patients with…

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Intrauterine Devices are a First-Line Option for Adolescents with Bleeding Disorders
 Intrauterine Devices are a First-Line Option for Adolescents with Bleeding Disorders 150 150 Mary Bates, PhD
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Among adolescents with heavy menstrual bleeding, study shows no difference in IUD expulsion rate between adolescents with bleeding disorders and those without. In a new study, researchers from Nationwide Children’s evaluated the use of intrauterine devices (IUDs) in two young women’s hematology clinics. They found that young women with bleeding disorders did not experience a…

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New Guidelines Offer a Clear Path for Expandable Endoprosthesis Use in Post-Sarcoma Limb Reconstruction
 New Guidelines Offer a Clear Path for Expandable Endoprosthesis Use in Post-Sarcoma Limb Reconstruction 150 150 Abbie Miller
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Limb salvage operation is the standard of care for pediatric extremity bone sarcomas. These tumors often occur during the second decade of life, when children are growing rapidly. Reconstructive surgeries must account for anticipated remaining growth and the potential for resulting limb inequity. Osteosarcoma and Ewing sarcoma are the most common primary malignant bone tumors,…

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