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Monthly Archives :

October 2026

New Consensus Guidance Addresses Antithrombotic Management in Infants With Congenital Heart Disease
 New Consensus Guidance Addresses Antithrombotic Management in Infants With Congenital Heart Disease 1024 670 Lauren Dembeck
By: Lauren Dembeck

New AATS consensus recommendations aim to reduce variation in antithrombotic testing, treatment, and monitoring for neonates and infants undergoing cardiac interventions. Antithrombotic management around cardiac procedures can be particularly challenging in neonates and infants, whose hemostatic systems differ from those of older children and adults. Limited population-specific evidence has contributed to substantial variation in practice…

New Single-Cell Immune Atlas Offers a Framework for Studying the Developing Immune System
 New Single-Cell Immune Atlas Offers a Framework for Studying the Developing Immune System 150 150 Abbie Miller and Mykyta Artomov, PhD
By: Abbie Miller and Mykyta Artomov, PhD

Collaboration between research teams at Nationwide Children’s Hospital, Washington University in St. Louis, and King’s College London has created a large-scale single-cell map of the human immune system that could provide an important framework for studying how immunity develops throughout life. Their findings are published in Immunity. The researchers, including co-corresponding authors Maxim N. Artyomov,…

Fertility Knowledge Gaps Continue Into Adulthood for People With Sickle Cell Disease
 Fertility Knowledge Gaps Continue Into Adulthood for People With Sickle Cell Disease 1024 683 Pam Georgiana
By: Pam Georgiana

Study findings support earlier, ongoing fertility education and counseling beginning in pediatric care. Sickle cell disease and its treatments can affect reproductive health, yet new research suggests patients may still have significant knowledge gaps about infertility when they reach adulthood. In a study published in the British Journal of Haematology, researchers surveyed 91 adults with…

MRI Study Points to Glymphatic System Changes in Pediatric Demyelinating Disorders
 MRI Study Points to Glymphatic System Changes in Pediatric Demyelinating Disorders 1024 445 Pam Georgiana
By: Pam Georgiana
MRI scans of a brain

Findings could help researchers understand how brain changes evolve over the course of disease. Relatively little is known about the brain’s glymphatic system. Researchers know that it helps remove waste products from the brain, but they are still learning how this recently discovered system may be affected by neurological disease. A new pilot study from…

Blood-Sparing Heart Surgery With Cardio-pulmonary Bypass: Limiting the Use of Blood Products for Repair of Congenital Heart Disease
 Blood-Sparing Heart Surgery With Cardio-pulmonary Bypass: Limiting the Use of Blood Products for Repair of Congenital Heart Disease 432 351 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES
close up of gloved hands in a surgical field holding surgical instruments

More than two decades of work suggest that not only can complicated cardiac surgeries be done without blood transfusions but the outcomes are likely just as good as the traditional approach. For the multidisciplinary team of clinicians at Nationwide Children’s, blood transfusion and cardio-pulmonary bypass (CPB) operations are not inseparable concepts. What started out as…