Monthly Archives :

June 2016

Often-Unreported MRI Finding May Indicate Neurodevelopmental Impairment in Premature Infants
Often-Unreported MRI Finding May Indicate Neurodevelopmental Impairment in Premature Infants 150 150 Jeb Phillips

Moderate-to-severe gyral maturation delay emerged as a significant predictor of overall neurodevelopmental delay in premature infants with extremely low birth weights Magnetic resonance imaging of the brain is increasingly used to predict neurodevelopmental outcomes in premature infants, but the existing systems of scoring those MRIs rely heavily on expert opinion. A recent study led by…

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For Infants Born Very Preterm, Transcatheter Device Closure of Patent Ductus Arteriosus is Feasible
For Infants Born Very Preterm, Transcatheter Device Closure of Patent Ductus Arteriosus is Feasible 150 150 Jeb Phillips

Optimal timing of procedures and reduction of adverse events are avenues for future study. Approximately half of babies born at less than 32 weeks of gestational age have persistent patent ductus arteriosus (PDA), a condition associated with higher odds of death and respiratory morbidity. When doctors choose to close the ductus, a percutaneous approach is…

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Specialty Pharmacy for Cystic Fibrosis Improves Access to Medication
Specialty Pharmacy for Cystic Fibrosis Improves Access to Medication 150 150 Abbie Roth

In a project started to increase the number of patients taking Orkambi®, access and adherence increases for all medications. The Nationwide Children’s Hospital Cystic Fibrosis (CF) Program cares for a large population of patients of all ages with cystic fibrosis.  The program has participated in many recent clinical trials, including one that led to the FDA approval…

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How Does Genomic Medicine Become a Reality for Children’s Health?
How Does Genomic Medicine Become a Reality for Children’s Health? 1024 575 Jan Arthur
conceptual art of DNA

Perhaps one of the most important initiatives to advance our understanding of pediatric disease is genomic analysis. Genomics encompasses all aspects of understanding the human genetic code, especially how genetic information contained in every human cell can be interpreted to prevent disease and customize treatments for nearly every type of illness. Genomic analysis allows us…

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A Novel, Promising Strategy for Diagnosing UTIs in Children
A Novel, Promising Strategy for Diagnosing UTIs in Children 150 150 Tiasha Letostak, PhD

Antimicrobial peptides may be effective biomarkers for diagnosing urinary tract infections in children. Urinary tract infections (UTIs) are one of the most common infections in children and account for millions of unplanned pediatrician and urgent care visits each year in the United States. Previous research has shown that antimicrobial peptides, referred to as AMPs, are…

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