Close
Enter your
text here

Uncategorized

What Pediatricians Should Know about Long COVID
 What Pediatricians Should Know about Long COVID 1024 683 Octavio Ramilo, MD
By:

More than 4 million children have tested positive for SARS-CoV-2 in the United States. According to the American Academy of Pediatrics, long-term effects from COVID-19 can be significant, regardless of initial disease severity. Medical providers across the nation, including here at Nationwide Children’s Hospital, are seeing an increase in cases of what is being called…

read more
Alarming Upward Trend in Black Youth Suicide From 2003 to 2017
 Alarming Upward Trend in Black Youth Suicide From 2003 to 2017 1024 683 Lauren Dembeck
By:
Sad black teenage girl

Prioritization of research aimed at identifying specific risk and protective factors associated with Black youth suicidal behavior is needed. In the United States, the rates of suicide and suicidal behavior among youth, children and adolescents 5-17 years of age, have been steadily increasing over the last decade, and Black youth, 5-12 years, are approximately two…

read more
Cylinder Mitral Valve Construct is a Safe and Durable Alternative for Young Patients
 Cylinder Mitral Valve Construct is a Safe and Durable Alternative for Young Patients 1024 752 Mary Bates, PhD
By:
Top-down view of heart valves

The new technique could potentially reduce the number of lifetime surgeries required by these patients, researchers say. In a new study, researchers from Nationwide Children’s Hospital report that pediatric patients who underwent cylinder mitral valve construct, a new technique for replacing the mitral valve, had improved left ventricular function over time. In addition, there were…

read more
Self-Administered Electronic Assessment Tool Helps Clinicians Screen for Pediatric Bleeding Disorders
 Self-Administered Electronic Assessment Tool Helps Clinicians Screen for Pediatric Bleeding Disorders 1024 684 JoAnna Pendergrass, DVM
By:
teen girl using cell phone

An electronic self-administered bleeding assessment tool is a time-saving measure to comprehensively evaluate a pediatric patient’s bleeding symptoms. Bleeding assessment tools (BATs), originally developed as research tools, are used clinically to comprehensively evaluate a patient’s bleeding symptoms. Along with clinical judgement, “BATs are used to discriminate between patients who do and do not have a…

read more
Using Virtual Reality Games to Reduce Dressing Change Pain in Pediatric Burn Patients
 Using Virtual Reality Games to Reduce Dressing Change Pain in Pediatric Burn Patients 934 401 JoAnna Pendergrass, DVM
By:

Smartphone-based virtual reality games can reduce dressing change pain for pediatric patients receiving outpatient burn treatment. According to the American Burn Association, burn injuries affect approximately 250,000 children in the United States each year. The pain associated with burn injuries extends beyond the injury itself; there is also significant pain from dressing changes, which can…

read more
How Can We Make Child Health Equitable?
 How Can We Make Child Health Equitable? 550 350 Jeb Phillips, Abbie Roth and Natalie Wilson
By:

Researchers in the Center for Child Health Equity and Outcomes Research at Nationwide Children’s Hospital are tackling this question by identifying health disparities and uncovering exactly how social drivers of health impact outcomes. “Health equity means that everyone has a fair and just opportunity to be as healthy as possible.” That’s how the Robert Wood…

read more
Targeting FSHD With Designed Antisense RNAs
 Targeting FSHD With Designed Antisense RNAs 1024 683 Abbie Roth
By:

Researchers describe small nuclear RNA antisense expression cassettes as a way to silence the DUX4 gene underlying facioscapulohumeral muscular dystrophy. Facioscapulohumeral muscular dystrophy (FSHD) arises from genetic and epigenetic changes that result in expression of the DUX4 gene in muscle. DUX4 is a developmental gene that is normally off in healthy muscle.  When expressed in…

read more
How to Make a Viral Vector
 How to Make a Viral Vector 150 150 Abbie Roth
By:

The Research Institute at Nationwide Children’s Hospital is the home to a current Good Manufacturing Practices (cGMP) Clinical Manufacturing Facility (CMF) that operates according to FDA cGMP Guidelines to ensure the safety of manufactured biologic products. The Space The CMF is a 9000-sq-ft space, including a 7500-sq-ft clean room suite with ISO Class 5/7/8 spaces…

read more