Monthly Archives :

December 2024

Exploring Pediatric Diffuse Alveolar Hemorrhage: Causes and Outcomes
Exploring Pediatric Diffuse Alveolar Hemorrhage: Causes and Outcomes 1024 575 Erin Gregory
Illustration of lungs on blue silhouette of upper chest on black background

In a groundbreaking study published in Pediatric Pulmonology, Sarah P. Cohen, MD, MS, and Katelyn Krivchenia, MD — both from Nationwide Children’s Hospital — along with their team investigate diffuse alveolar hemorrhage (DAH) in children, a rare but life-threatening condition involving bleeding into the lungs. The study unveils the complex interplay of causes and outcomes associated…

Challenges in Clinical Decision-Making for Patients with Spinal Muscular Atrophy
Challenges in Clinical Decision-Making for Patients with Spinal Muscular Atrophy 1024 683 Mary Bates, PhD

There are three approved genetic therapies for SMA, but little guidance in treatment selection. Spinal muscular atrophy (SMA) was once a leading cause of inherited infant death in the United States. Today, there are three genetic therapies approved by the Food and Drug Administration to treat SMA — but no clinical trials directly comparing treatment…

Making the Case for Interdisciplinary BPD Care
Making the Case for Interdisciplinary BPD Care 150 150 Abbie Miller

A new review highlights benefits of interdisciplinary BPD management and offers advice on how program development. Bronchopulmonary dysplasia (BPD) affects more than 40% of preterm infants and is the most common lung disease in infancy. There are long term consequences and comorbidities associated with BPD, including hospitalization, re-hospitalization, emergency department visits, recurrent wheezing and neurodevelopmental…

Pediatric Obstructive Sleep Apnea Diagnosis and Treatment: What You Need to Know
Pediatric Obstructive Sleep Apnea Diagnosis and Treatment: What You Need to Know 1024 575 JoAnna Pendergrass, DVM
Color image of young boy asleep in bed

Pediatric obstructive sleep apnea, a common condition in children, is definitively diagnosed with sleep studies and can be treated through various modalities, depending on disease severity. Obstructive sleep apnea (OSA) is a disorder characterized by snoring, gas exchange abnormalities and disrupted sleep, with near-complete airway blockage. Affecting approximately 1% to 4% of preschool children, with…

How Does Cannabis Use During Pregnancy Affect Children?
How Does Cannabis Use During Pregnancy Affect Children? 1024 683 Katelyn Scott

A recent study shows that prenatal exposure to cannabis is associated with poorer thinking skills and behaviors.  In a study published in JAMA Pediatrics, researchers found prenatal cannabis exposure was associated in early childhood with poorer thinking skills and behaviors such as impulse control, paying attention and planning ability, and more aggressive behavior, all of…

The Current and Future State of Scoliosis Care and Research
The Current and Future State of Scoliosis Care and Research 1024 683 Madison Storm

In the United States alone, scoliosis affects an estimated 7 million people – just under twice the population of Los Angeles – according to the Scoliosis Research Society. Each year, an estimated 30,000 children begin wearing braces for treatment.  Over time, the treatments available for different types of scoliosis have continued to advance, in large…

Advancing Care for Infants with Hypoplastic Left Heart Syndrome: New Insights into Maternal and Community Health Factors
Advancing Care for Infants with Hypoplastic Left Heart Syndrome: New Insights into Maternal and Community Health Factors 1024 537 Pam Georgiana

Nationwide Children’s Heart Center explores the impact of maternal and social determinants of health on congenital heart disease. While maternal-fetal environment factors are known to impact outcomes in babies who receive the traditional Norwood surgery to treat hypoplastic left heart syndrome (HLHS), there is little research on how the maternal-fetal environment affects outcomes after the…

1 Trillion Cells: Nationwide Children’s Reaches New Milestone for Universal-Donor NK Cell Studies
1 Trillion Cells: Nationwide Children’s Reaches New Milestone for Universal-Donor NK Cell Studies 1024 649 Abbie Miller

The Biologics Manufacturing Resource, Nationwide Children’s Cell and Tissue cGMP manufacturing facility, recently achieved a major milestone. The resource has now delivered more than 1 trillion universal donor natural killer (NK) cells to patients. These NK cells are being studied in clinical trials to learn if they can help children and adults with cancer. “This…