Kidney Transplant Program and the Psychosocial Power Team: Expanding Care Through Collaboration
Kidney Transplant Program and the Psychosocial Power Team: Expanding Care Through Collaboration 1024 683 Leslie Feldman

In the United States, the availability of psychosocial services within pediatric nephrology centers varies widely – despite a well-documented necessity for the provision of holistic care. For the most part, the landscape of available psychosocial services within pediatric nephrology care is poorly characterized. However,…

read more
NIDDK Grant Awarded to Launch Integrated Islet Distribution Program Islet Isolation Center
NIDDK Grant Awarded to Launch Integrated Islet Distribution Program Islet Isolation Center 150 150 Katie Brind'Amour, PhD, MS, CHES

A Nationwide Children’s Hospital research team has received federal funding to become a hub for the isolation and distribution of high-quality human islet cells for the diabetes research community. Since joining Nationwide Children’s Hospital in 2022 as director of the Islet Cell Isolation Program,…

read more
Fetal Surgery for Spina Bifida: Supporting A Bright Future Closer to Home
Fetal Surgery for Spina Bifida: Supporting A Bright Future Closer to Home 150 150 Alaina Doklovic

During her 20-week ultrasound appointment, Brittany Badenhop learned her baby had spina bifida, a term used to describe many disorders that occur during the development of the central nervous system. Spina bifida occurs very early on in a pregnancy as the embryo forms. Brittany…

read more
Supporting Children With Interstitial and Rare Lung Disease
Supporting Children With Interstitial and Rare Lung Disease 1024 687 Abbie Miller

In pediatrics, some causes of lung dysfunction, while rare in their own right, are fairly common – such as cystic fibrosis, bronchopulmonary dysplasia and asthma. Interstitial and rare lung disease (IRLD) is an umbrella term for 30-50 diseases that affect children worldwide. IRLD may…

read more
New Fast, Reliable Model Tests Patient Response to Novel Treatments
New Fast, Reliable Model Tests Patient Response to Novel Treatments 150 150 Madison Storm

It’s well-known that treatments work for some patients and don’t for others, and this can be a real challenge when it comes to rare neurogenerative disorders. Dr. Kathrin Meyer and her lab established a faster, reliable in vitro model to investigate why. Recent research…

read more
Coexistence of Different Telomere Maintenance Mechanisms in Pediatric High-Grade Glioma Tumors
Coexistence of Different Telomere Maintenance Mechanisms in Pediatric High-Grade Glioma Tumors 1024 504 Lauren Dembeck

Due to within-tumor heterogeneity, telomere-based therapeutic interventions will likely need to target both known telomere maintenance mechanisms to prevent resistance and recurrence.   Normal differentiated somatic cells can divide only a limited number of times due to loss of the physical ends of their…

read more
A Decade of Evidence: The SIMPLE Program Shows Continued Success
A Decade of Evidence: The SIMPLE Program Shows Continued Success 1024 575 Pam Georgiana

In 2010, Nationwide Children’s Hospitals NICU leaders observed that infant feeding practices varied depending on the provider, resulting in significant variations in milestones and length of hospital stays (LOHS). They asked Sudarshan R. Jadcherla, MD, and Erika Osborn, NNP, to partner with stakeholders, including…

read more
Girl sitting on a bench with her phone smiling.
User Experiences With Subcutaneous Depot Medroxyprogesterone Acetate
User Experiences With Subcutaneous Depot Medroxyprogesterone Acetate 1024 683 Mary Bates, PhD

Survey reveals high satisfaction among adolescents and young adults using subcutaneous DMPA Depot medroxyprogesterone acetate (DMPA) is a progestin-only injectable contraceptive that is used as birth control method and in the treatment of heavy or painful menstrual periods, endometriosis, and for menstrual suppression. DMPA…

read more
Exploring the Clinical Journey of Children With Primary Hyperoxaluria
Exploring the Clinical Journey of Children With Primary Hyperoxaluria 150 150 JoAnna Pendergrass, DVM

Children with primary hyperoxaluria, a rare genetic disease, navigate a complicated clinical journey that includes a heavy reliance on health care services and usage of multidisciplinary care. Primary hyperoxaluria (PH) is a rare disease caused by genetic mutations of enzymes that regulate hepatic glyoxylate…

read more
Julie Samora, MD
Diagnosing and Treating Cubital Tunnel Syndrome in Adolescents
Diagnosing and Treating Cubital Tunnel Syndrome in Adolescents 1024 575 Mary Bates, PhD

Surgery leads to improved outcomes in pediatric patients with symptoms of cubital tunnel syndrome, even when electrodiagnostic studies are negative. In a new study, researchers from Nationwide Children’s Hospital demonstrate that pediatric patients who underwent surgical decompression for cubital tunnel syndrome achieved good resolution…

read more
Counseling Families of Patients with Hypoplastic Left Heart Syndrome
Counseling Families of Patients with Hypoplastic Left Heart Syndrome 150 150 Mary Bates, PhD

A new survey investigates how palliation strategies have changed in the last ten years. Approximately ten years ago, researchers at Nationwide Children’s Hospital surveyed pediatric cardiac providers regarding initial counseling for families of patients with hypoplastic left heart syndrome (HLHS). Given the evolution of…

read more
Using Machine Learning to Classify Treatment Approaches for Infants with Bronchopulmonary Dysplasia
Using Machine Learning to Classify Treatment Approaches for Infants with Bronchopulmonary Dysplasia 1024 683 Pam Georgiana

We don’t yet know the best way to help infants with severe bronchopulmonary dysplasia (BPD) breathe using ventilators. Currently, doctors across the country and around the world use a variety of different approaches.  These variations depend on the severity of a patient’s medical condition,…

read more
Smiling baby with Down syndrome
Changing the Odds: Survival Trends in Children With Down Syndrome and Congenital Heart Defects
Changing the Odds: Survival Trends in Children With Down Syndrome and Congenital Heart Defects 1024 683 Pam Georgiana

About half of the children born with Down syndrome also have congenital heart defects (CHD). As a transplant cardiologist, Lydia K Wright, MD, wanted to learn if CHD was still the most significant mortality risk for these patients before age five. [1] “Our aim…

read more
small baby with nose canula
Safe, Minimally Invasive Upper Urinary Tract Surgery for Infants
Safe, Minimally Invasive Upper Urinary Tract Surgery for Infants 1024 575 Patti Doud

Evidence supports robotic surgery as a safe approach to upper urinary tract procedures in infants 6 months or younger. While robotic surgery has risen in popularity and feasibility for procedures in both older children and adults alike, there has been little data to determine…

read more
Teen girl with backpack
Ask A Specialist: What Are the Recommendations for Sexually Transmitted Infections (STI) Screening in Primary Care?
Ask A Specialist: What Are the Recommendations for Sexually Transmitted Infections (STI) Screening in Primary Care? 1024 575 Cynthia Holland-Hall, MD

STI screening is recommended for all sexually active adolescents. According to the American Academy of Pediatrics, nearly 1 in 4 teens have an STI. Safe sexual practices and routine screening can prevent these infections – that’s where health care providers come in. By offering…

read more
Color photo of Black father holding infant on shoulder in front of nursery background with clouds on the wall
Fertility Concerns in Boys and Men With Sickle Cell Disease
Fertility Concerns in Boys and Men With Sickle Cell Disease 1024 575 Mary Bates, PhD

Sickle cell disease and its treatments may impact fertility, but more research is needed to help counsel this population. Sickle cell disease (SCD) affects approximately 100,000 Americans, most of whom belong to underserved, minority populations. Advances in disease-modifying therapies, such as hydroxyurea, have led…

read more
Assessing Respiratory Stability in Infants Hospitalized with Bronchopulmonary Dysplasia
Assessing Respiratory Stability in Infants Hospitalized with Bronchopulmonary Dysplasia 1024 683 Mary Bates, PhD

The Behavioral Signs of Respiratory Instability Scale is a valid, reliable measure of respiratory status and developmental ability. In a new study, researchers at Nationwide Children’s evaluated the Behavioral Signs of Respiratory Instability (BSRI) Scale, which was developed as an objective measure of developmental…

read more
Featured Researcher — Nilsa Ramirez, MD
Featured Researcher — Nilsa Ramirez, MD 150 150 Katie Brind'Amour, PhD, MS, CHES

Nilsa Del Carmen Ramirez Milan, MD, director of the Biopathology Center at Nationwide Children’s Hospital, leads the biorepository team that receives about 1,000 new specimens each day. These must be processed and stored properly—together with the rest of the biobank’s > 6 million specimens.…

read more
Home Infusions of Infliximab for Inflammatory Bowel Disease
Home Infusions of Infliximab for Inflammatory Bowel Disease 1024 683 Mary Bates, PhD

With a standardized care approach, home infusions may be an effective alternative to hospital-based infusions. Pediatric inflammatory bowel disease (IBD) is often treated with infusions of infliximab in a hospital setting. However, these can be costly and present time and travel barriers to patients…

read more
Smiling boy outside
Expanding Use of Trikafta for Cystic Fibrosis to Patients as Young as 2 Years Old
Expanding Use of Trikafta for Cystic Fibrosis to Patients as Young as 2 Years Old 1024 683 Karen McCoy, MD

When I first started my pulmonary training, the average life expectancy in the United States was about 70 years, and the average life expectancy for someone with cystic fibrosis (CF) was 14 years! Intense study and pursuit of consistent care across the country yielded…

read more