COVID-19

Learning in Real Time to Overcome COVID-19 and MIS-C
Learning in Real Time to Overcome COVID-19 and MIS-C 1024 491 Natalie Wilson
Illustrations of clock faces at different times and angles

When multisystem inflammatory syndrome in children (MIS-C) emerged in May 2020, the new condition made headlines. Although rare, MIS-C can appear in kids about a month after they’ve recovered from infections with SARS-CoV-2, the virus that causes COVID-19 — even if they haven’t felt sick at all. “We don’t know why some children develop MIS-C,”…

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What Pediatricians Should Know about Long COVID
What Pediatricians Should Know about Long COVID 1024 683 Octavio Ramilo, MD

More than 4 million children have tested positive for SARS-CoV-2 in the United States. According to the American Academy of Pediatrics, long-term effects from COVID-19 can be significant, regardless of initial disease severity. Medical providers across the nation, including here at Nationwide Children’s Hospital, are seeing an increase in cases of what is being called…

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Molecular Toolset: Real-Time Screening for SARS-CoV-2 Variants
Molecular Toolset: Real-Time Screening for SARS-CoV-2 Variants 1024 683 Lauren Dembeck

Tracking variants of concern or interest is critical to inform public health decisions and to ensure patients receive the best available COVID-19 treatments for SARS-CoV-2 infections. Researchers at Nationwide Children’s Hospital and The Ohio State University (OSU) have developed a set of mutation-specific tests with same-day reporting that can detect five variants of concern (VOCs)…

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EVALI and MIS-C: Overlapping Diagnoses
EVALI and MIS-C: Overlapping Diagnoses 1024 575 Mary Bates, PhD

Taking a thorough history can differentiate these similarly presenting conditions. In a new report, researchers from Nationwide Children’s Hospital describe six patients admitted to the hospital with concerns for MIS-C who were later diagnosed with EVALI. The researchers discuss the factors that led them to differentiate between the two disorders and arrive at the correct…

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9 Facts About the COVID-19 Vaccine
9 Facts About the COVID-19 Vaccine 1024 683 Abbie Roth

COVID-19 is a disease caused by the SARS-CoV-2 virus. In the United States, three vaccines are approved for emergency use, those produced by Pfizer, Moderna and Johnson & Johnson (J&J). These vaccines dramatically reduce your risk of getting severely ill or dying from COVID-19. The vaccines are also being shown to reduce the spread of…

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Lessons Learned Through a Global Pandemic
Lessons Learned Through a Global Pandemic 1024 683 Lauren Bakaletz, PhD
Lauren Bakaletz, PhD

As a microbiologist and vaccinologist, I spend nearly every day thinking about viruses and bacteria and the diseases they cause, as well as how to best prevent them from doing so. While in graduate school, we were taught about the great ‘flu’ pandemic of 1918 that infected one-third of the world’s population and killed 20-50…

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Introducing a New SARS-CoV-2 Vaccine Candidate
Introducing a New SARS-CoV-2 Vaccine Candidate 1024 512 Abbie Roth
coronavirus

The new vaccine candidate takes advantage of the long and successful history of the measles vaccine. A team of researchers from The Ohio State University and Nationwide Children’s have built a novel vaccine candidate against SARS-CoV-2. The candidate, published in Proceedings of the National Academy of Sciences (PNAS), used the measles vaccine as a vector…

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One Year Reflection: Behavioral Health Pavilion Adds to Industry-Leading Model of Care During Pandemic
One Year Reflection: Behavioral Health Pavilion Adds to Industry-Leading Model of Care During Pandemic 1024 538 Kaitlin Hall

The full impact of COVID-19 on children’s mental health likely won’t be known for some time. But even before the pandemic, pediatric mental health was in a national crisis, with one in five children living with a mental illness, and suicide the second leading cause of death for children 10 and older. That means the…

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COVID-19 and the Heart: SARS-CoV-2-Associated Myocardial Infection
COVID-19 and the Heart: SARS-CoV-2-Associated Myocardial Infection 150 150 Simon Lee

Myocardial infection following COVID-19 illness has made headlines. Simon Lee, MD, tackles some commonly asked questions about MIS-C and isolated myocarditis after COVID-19 recovery.

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Boosting Natural Killer Cells for the Treatment of COVID-19
Boosting Natural Killer Cells for the Treatment of COVID-19 150 150 Lauren Dembeck

Natural killer cells — critical for immune surveillance and host defense — have an important role in cancer immunotherapy and antiviral responses. While driving to the laboratory one day, Brian Tullius, MA, MD, a fourth-year bone marrow transplant and cell therapies fellow at Nationwide Children’s in the Lee Lab, had an epiphany. “I thought, ‘wait…

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What Kids and Kidneys Can Teach Pediatricians About Racism in America
What Kids and Kidneys Can Teach Pediatricians About Racism in America 1024 575 Ray Bignall

O.N. Ray Bignall II, MD, FAAP, director of Kidney Health Advocacy and Community Engagement, explores how “race modifiers,” structural racism and health disparities are perpetuated in kidney care for kids, highlighting important areas primed for change.

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How Has the COVID-19 Pandemic Affected Measles Vaccination Rates?
How Has the COVID-19 Pandemic Affected Measles Vaccination Rates? 1024 575 Mary Bates, PhD
Toddler playing with toys

Researchers are concerned about declining vaccination rates in the Nationwide Children’s Hospital pediatric primary care network. One consequence of the COVID-19 pandemic is that more families are putting off their children’s preventive care visits, causing pediatric providers to worry about missed vaccines. In a recent study published in Pediatrics, researchers at Nationwide Children’s evaluated changes in…

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Taking on Bronchiolitis in the Age of COVID-19
Taking on Bronchiolitis in the Age of COVID-19 1024 575 Eric Butterman
small baby with nose canula

In a recent episode of PediaCast CME, Drs. Asuncion Mejias and Gerd McGwire address the diagnosis and management of bronchiolitis – and special considerations during the COVID-19 pandemic. Bronchiolitis is the leading cause of hospitalizations for young infants around the world, and in a year with a respiratory pandemic, everyone is a little uneasy about…

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Study of Children With COVID-19 Admitted to US and Canadian Pediatric Intensive Care Units
Study of Children With COVID-19 Admitted to US and Canadian Pediatric Intensive Care Units 1024 683 Abbie Roth

Publication examines the characteristics and outcomes of children with COVID-19 who were admitted to North American PICUs. While two studies from Wuhan, China, have indicated that COVID-19 disease burden and severity seems to be lower in children, it remains to be seen how children around the world will fare as the pandemic progresses. In March…

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Missing Connections: A Reflection on Residency During a Global Pandemic
Missing Connections: A Reflection on Residency During a Global Pandemic 150 150 Nimisha Bajaj, MD

I am a first-year pediatrics resident at Nationwide Children’s Hospital, and SARS-CoV-2 has turned my world upside down. I support social distancing measures, at least until broader public health interventions have been universally implemented. But as a physician in training, the pandemic has affected many aspects of my life, including patient care, residency training and…

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How Practical COVID-19 Education for Community Providers Sprang From a Pediatric Behavioral Health Project ECHO
How Practical COVID-19 Education for Community Providers Sprang From a Pediatric Behavioral Health Project ECHO 1024 575 Katie Brind'Amour, PhD, MS, CHES

When Partners For Kids® (PFK) and Nationwide Children’s Hospital launched Project ECHO in 2018, they did it to help community providers cope with common behavioral health conditions in their patient populations. Unexpectedly, it became a tool to supply Ohio physicians with some of the most proactive education in the nation about adapting their business practices to accommodate COVID-19-related…

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