Inside the Science of Pediatric Lung Disease

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How Can We Increase the HPV Vaccination Rate?
 How Can We Increase the HPV Vaccination Rate? 150 150 Michael T. Brady, MD
By: Michael T. Brady, MD

Cancer is a terrifying diagnosis for a patient to receive or a doctor to give. So it would make sense that a vaccine proven to prevent cancer would be welcomed by everyone. The human papillomavirus (HPV) vaccine could prevent 28,500 HPV-related cancer cases – cervical, vaginal,…

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How to Integrate Genomics into Clinical Practice
 How to Integrate Genomics into Clinical Practice 150 150 Abbie Miller
By: Abbie Miller

Recommendations from the Clinical Genetics Think Tank outline five key areas of focus for bringing genome and exome sequencing into the clinic. Clinical genome and exome sequencing (CGES) as a diagnostic tool is altering practice for clinical geneticists, genetic counselors and other clinical specialists.…

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In Sight: Two Stage Surgery for Epilepsy
 In Sight: Two Stage Surgery for Epilepsy 150 150 Abbie Miller
By: Abbie Miller

Surgery proves to be a viable option for patients with medically refractory epilepsy. Childhood onset epilepsy affects 1 percent of children worldwide. About 25 to 30 percent of these patients will have medically refractory epilepsy, continuing to have seizures despite using two or more antiseizure medications.…

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Great Minds Aren’t Thinking Alike About Asthma Care
 Great Minds Aren’t Thinking Alike About Asthma Care 150 150 Brianne Moore
By: Brianne Moore

A recent audit of the Pediatric Hospital Information System using template matching finds wide variation in care provided to pediatric asthma patients. While asthma is a common and manageable disease, nine people still die from asthma each day. It is well known that asthma…

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One Dose Probiotic Biofilm Protects Against NEC
 One Dose Probiotic Biofilm Protects Against NEC 150 150 Kevin Mayhood
By: Kevin Mayhood

Probiotic biofilm enables the beneficial bacteria to withstand stomach acid, promote microbial activity and decrease intestinal inflammation. A single dose of a probiotic biofilm grown on microspheres prevented or significantly reduced the severity of necrotizing enterocolitis (NEC) in animal models of the disease, researchers…

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Novel Practice Pathway Addresses Problem Behaviors Among Patients With Autism
 Novel Practice Pathway Addresses Problem Behaviors Among Patients With Autism 150 150 Kevin Mayhood
By: Kevin Mayhood

Pediatricians urged to investigate underlying causes. Issues causing children with autism spectrum disorder to be irritable or belligerent can be difficult for parents, teachers and other care providers to uncover. And, wait times to see a specialist may leave a child frustrated, distressed or…

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How Can You Optimize Care for Homeless Patients?
 How Can You Optimize Care for Homeless Patients? 150 150 Tiasha Letostak, PhD
By: Tiasha Letostak, PhD

A recent policy statement from the AAP describes how pediatricians can help improve the health and well-being of homeless children in America. As of 2014, the National Center on Family Homelessness reported that a staggering 2.5 million children are homeless each year in America, a historic…

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New Guidelines Better Diagnose Common GI Disorders
 New Guidelines Better Diagnose Common GI Disorders 150 150 Jeb Phillips
By: Jeb Phillips

The new Rome IV criteria offer guidance to common but often misunderstood conditions. Because there are no clear causes of functional gastrointestinal disorders (FGIDs), diagnosis and treatment can be difficult. Some physicians and parents may doubt the disorders exist at all, although pediatric gastroenterologists…

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A Better Approach to Prescribing Medication
 A Better Approach to Prescribing Medication 150 150 Jeb Phillips
By: Jeb Phillips

A small change in the way a doctor prescribes a medication can make a big difference. Officials from the accountable care organization Partners For Kids use this example all the time: Abilify, a behavioral health drug, is usually priced per pill, not by strength of…

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Best Practices for Research Recruitment and Retention
 Best Practices for Research Recruitment and Retention 150 150 Tiasha Letostak, PhD
By: Tiasha Letostak, PhD

You can’t obtain study data without participants. From initial design and promotion to communication tactics and patient satisfaction, here are some strategies to ensure success. Advancing pediatric research depends on successful recruitment and retention of study participants. Unfortunately, 9 out of 10 trials end…

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Childhood Kidney Stones: Their Surprising Connection to Future Disease
 Childhood Kidney Stones: Their Surprising Connection to Future Disease 150 150 Jeb Phillips
By: Jeb Phillips

Once thought to be an adult condition, urinary stone disease is increasingly found in children – and may be related to the development of cardiovascular disease, chronic kidney disease and low bone density. By one well-regarded estimate, the risk of developing urinary stone disease…

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Illustration depicting cancer immunotherapy: a person rides atop a large pink, textured cancer cell while holding loops of rope wrapped around the cell, suggesting control or targeting of cancer. Additional cancer-like cells float in the background against blue radial light beams, symbolizing efforts to harness the immune system to fight cancer.
Harnessing the Immune System: Has the Cure for Cancer Been Within Us All Along?
 Harnessing the Immune System: Has the Cure for Cancer Been Within Us All Along? 1024 575 Abbie Miller
By: Abbie Miller

By learning to manipulate the immune system to target cancer cells, clinician-scientists are ushering in a new era in cancer treatments. The advances in cancer immunotherapy have been headline-making, and some clinical studies have produced stories of near-miraculous recoveries. From the immunotherapy drug credited…

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virtual reality landscape
Changing the Game: Virtual Reality Distracts From Pain, Transforming the Patient Experience
 Changing the Game: Virtual Reality Distracts From Pain, Transforming the Patient Experience 844 487 Gina Bericchia
By: Gina Bericchia

A first-of-its-kind virtual reality experience from the hemophilia team and design experts at Nationwide Children’s Hospital and The Ohio State University distracts patients with an immersive environment of penguins, pirates and hermit crabs during infusions and other procedures. A pilot study is testing the…

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Minimally-Invasive Technology Proving Itself in Epilepsy Procedures
 Minimally-Invasive Technology Proving Itself in Epilepsy Procedures 150 150 Kevin Mayhood
By: Kevin Mayhood

MRI-guided stereotactic laser ablation may become the option of choice for appropriate patients. MRI-guided stereotactic laser ablation is proving comparable to open surgery in several procedures aimed at controlling epilepsy, researchers report. Importantly, patients’ recovery is considerably easier and shorter than recuperation from traditional…

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Use Caution When Prescribing a Gluten-Free Diet
 Use Caution When Prescribing a Gluten-Free Diet 150 150 Kevin Mayhood
By: Kevin Mayhood

A gluten-free diet makes diagnosing underlying conditions difficult and can leave potential, long-term consequences unaddressed. The growing popularity of a gluten-free diet among adults appears to be spilling over to children, with help from the pediatrician’s office. “An increasing number of primary care physicians,…

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Oligodendrocytes Induce Motor Neuron Death in ALS
 Oligodendrocytes Induce Motor Neuron Death in ALS 150 150 Jeb Phillips
By: Jeb Phillips

A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this discovery may point the way toward therapeutic timing and targets. A number of studies over the…

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Personal, Familial and Social Factors Surrounding Child Suicide
 Personal, Familial and Social Factors Surrounding Child Suicide 150 150 Brianne Moore
By: Brianne Moore

As suicide rates among children climb, researchers publish the first study exclusively focused on the precipitating circumstances of children and young adolescents who die by suicide. According to the Centers for Disease Control and Prevention (CDC), suicide was the 10th leading cause of death for…

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A Painful Reality: Care Providers Tend to Underestimate Pain During Pediatric Burn Dressing Changes
 A Painful Reality: Care Providers Tend to Underestimate Pain During Pediatric Burn Dressing Changes 150 150 Krista Wheeler
By: Krista Wheeler

Researchers call for an updated pain scale. Dressing changes have been identified as one of the major contributors to perceived pain during burn care, and so it is important that pain be assessed accurately. But a new study from the Center for Pediatric Trauma Research in…

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What Pediatricians Need to Know About the New Meningococcal B Vaccine
 What Pediatricians Need to Know About the New Meningococcal B Vaccine 150 150 Michael T. Brady, MD
By: Michael T. Brady, MD

Michael T. Brady, MD, infectious diseases specialist at Nationwide Children’s Hospital and primary author of the recent American Academy of Pediatrics position paper on the meningococcal B vaccine, shares what you need to know about this controversial vaccine. Meningococcal serotype B (MenB) causes the…

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Nine Factors for Predicting the Duration of Post-Concussion Symptoms
 Nine Factors for Predicting the Duration of Post-Concussion Symptoms 150 150 Jeb Phillips
By: Jeb Phillips

Concussion recovery is poorly understood, but new research suggests that some factors are predictive of recovery time. Several factors, including continued physical activity following a concussion, worsening symptoms from the time of injury to the time a patient seeks care, and a previous history…

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