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What Do Space Rocks Have to Do With Preterm Birth?
 What Do Space Rocks Have to Do With Preterm Birth? 150 150 Abbie Miller
By: Abbie Miller

A brief history of nanobacteria and their implications for human health. I remember when nanobacteria were a really big deal. Press-conference-by-POTUS-about-evidence-of-extraterrestrial-life-level big deal. I hadn’t thought much about them until recently, when they made a surprise appearance in a presentation on idiopathic preterm birth by Irina…

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New Study Points to a Possible Cause of Many Preterm Births
 New Study Points to a Possible Cause of Many Preterm Births 150 150 Jeb Phillips
By: Jeb Phillips

The discovery that small calcium deposits in fetal membranes may lead to a mother’s water breaking prematurely suggests that dietary or other interventions could prevent those preterm births. Most spontaneous preterm births do not have causes that are easy to identify. Physicians frequently have…

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Should Hormone Therapy be Considered for Inappropriate Sexual Behavior in Adolescents With Autism Spectrum Disorder?
 Should Hormone Therapy be Considered for Inappropriate Sexual Behavior in Adolescents With Autism Spectrum Disorder? 150 150 Jeb Phillips
By: Jeb Phillips

Families worry when children with autism spectrum disorder display inappropriate sexual behaviors, but specialists say hormonal suppression should not be the first-line approach. Leena Nahata, MD, a pediatric endocrinologist at Nationwide Children’s Hospital, has seen this kind of case in her own practice, so she suspects…

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Stronger Together: A Multi-institutional Database Is Connecting Down Syndrome Clinics for Better Outcomes
 Stronger Together: A Multi-institutional Database Is Connecting Down Syndrome Clinics for Better Outcomes 1024 575 Stephanie Santoro, MD
By: Stephanie Santoro, MD

Due to medical advances, people with Down syndrome are living longer than ever before. This increased life expectancy has nearly doubled in the past 25 years. The National Down Syndrome Society estimates that 400,000 people with Down syndrome are living in the United States.…

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From Military Zones to Pediatric Trauma Centers, Implementing Massive Transfusion Protocols
 From Military Zones to Pediatric Trauma Centers, Implementing Massive Transfusion Protocols 150 150 Abbie Miller
By: Abbie Miller

While military and adult research has shown massive transfusion protocols to be lifesaving, implementation and validation in pediatrics lags. When someone is critically injured with life-threatening bleeding, the primary objective of the care team is to stop the bleeding and replace the lost blood.…

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Pediatricians and Subspecialists May Need to Up Their ADHD Game
 Pediatricians and Subspecialists May Need to Up Their ADHD Game 150 150 Kevin Mayhood
By: Kevin Mayhood

From sixth to eighth grade, Stacy Gibson sought out kids he knew had attention-deficit/hyperactivity disorder and bought their Ritalin or Adderall, sometimes by the handful. “I would party all night,then I’d take the pills to get through class. It gave me a rush of…

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Solving the Problem of Managing Big Genomic Data
 Solving the Problem of Managing Big Genomic Data 150 150 Abbie Miller
By: Abbie Miller

Researchers at Nationwide Children’s Hospital complete a first-of-its-kind project to evaluate a large-scale genomic data management system on the scale of up to one million genomes. The influx of genomics data resulting from the increasing affordability of whole exome/genome sequencing and President Obama’s Precision…

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Diagnosing GERD in Neonates? Be Cautious
 Diagnosing GERD in Neonates? Be Cautious 150 150 Jeb Phillips
By: Jeb Phillips

Gastroesophageal reflux disease is likely over-diagnosed in neonates, leading to unnecessary and harmful treatment. Approximately 10 percent of infants born preterm in the United States are diagnosed with gastroesophageal reflux disease (GERD). But it’s almost certain that not all of those babies actually have GERD, say…

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A New Use for Kangaroo Care
 A New Use for Kangaroo Care 150 150 Kevin Mayhood
By: Kevin Mayhood

A parent’s touch reduces agitation, allows infants and toddlers to remain extubated after heart surgery. A small percentage of babies and young children who have undergone congenital cardiac surgery and early tracheal extubation are treated with a calming parent’s touch at Nationwide Children’s Hospital…

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How Can We Increase the HPV Vaccination Rate?
 How Can We Increase the HPV Vaccination Rate? 150 150 Michael T. Brady, MD
By: Michael T. Brady, MD

Cancer is a terrifying diagnosis for a patient to receive or a doctor to give. So it would make sense that a vaccine proven to prevent cancer would be welcomed by everyone. The human papillomavirus (HPV) vaccine could prevent 28,500 HPV-related cancer cases – cervical, vaginal,…

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How to Integrate Genomics into Clinical Practice
 How to Integrate Genomics into Clinical Practice 150 150 Abbie Miller
By: Abbie Miller

Recommendations from the Clinical Genetics Think Tank outline five key areas of focus for bringing genome and exome sequencing into the clinic. Clinical genome and exome sequencing (CGES) as a diagnostic tool is altering practice for clinical geneticists, genetic counselors and other clinical specialists.…

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In Sight: Two Stage Surgery for Epilepsy
 In Sight: Two Stage Surgery for Epilepsy 150 150 Abbie Miller
By: Abbie Miller

Surgery proves to be a viable option for patients with medically refractory epilepsy. Childhood onset epilepsy affects 1 percent of children worldwide. About 25 to 30 percent of these patients will have medically refractory epilepsy, continuing to have seizures despite using two or more antiseizure medications.…

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Great Minds Aren’t Thinking Alike About Asthma Care
 Great Minds Aren’t Thinking Alike About Asthma Care 150 150 Brianne Moore
By: Brianne Moore

A recent audit of the Pediatric Hospital Information System using template matching finds wide variation in care provided to pediatric asthma patients. While asthma is a common and manageable disease, nine people still die from asthma each day. It is well known that asthma…

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One Dose Probiotic Biofilm Protects Against NEC
 One Dose Probiotic Biofilm Protects Against NEC 150 150 Kevin Mayhood
By: Kevin Mayhood

Probiotic biofilm enables the beneficial bacteria to withstand stomach acid, promote microbial activity and decrease intestinal inflammation. A single dose of a probiotic biofilm grown on microspheres prevented or significantly reduced the severity of necrotizing enterocolitis (NEC) in animal models of the disease, researchers…

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Novel Practice Pathway Addresses Problem Behaviors Among Patients With Autism
 Novel Practice Pathway Addresses Problem Behaviors Among Patients With Autism 150 150 Kevin Mayhood
By: Kevin Mayhood

Pediatricians urged to investigate underlying causes. Issues causing children with autism spectrum disorder to be irritable or belligerent can be difficult for parents, teachers and other care providers to uncover. And, wait times to see a specialist may leave a child frustrated, distressed or…

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How Can You Optimize Care for Homeless Patients?
 How Can You Optimize Care for Homeless Patients? 150 150 Tiasha Letostak, PhD
By: Tiasha Letostak, PhD

A recent policy statement from the AAP describes how pediatricians can help improve the health and well-being of homeless children in America. As of 2014, the National Center on Family Homelessness reported that a staggering 2.5 million children are homeless each year in America, a historic…

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New Guidelines Better Diagnose Common GI Disorders
 New Guidelines Better Diagnose Common GI Disorders 150 150 Jeb Phillips
By: Jeb Phillips

The new Rome IV criteria offer guidance to common but often misunderstood conditions. Because there are no clear causes of functional gastrointestinal disorders (FGIDs), diagnosis and treatment can be difficult. Some physicians and parents may doubt the disorders exist at all, although pediatric gastroenterologists…

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A Better Approach to Prescribing Medication
 A Better Approach to Prescribing Medication 150 150 Jeb Phillips
By: Jeb Phillips

A small change in the way a doctor prescribes a medication can make a big difference. Officials from the accountable care organization Partners For Kids use this example all the time: Abilify, a behavioral health drug, is usually priced per pill, not by strength of…

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Best Practices for Research Recruitment and Retention
 Best Practices for Research Recruitment and Retention 1024 575 Tiasha Letostak, PhD
By: Tiasha Letostak, PhD

You can’t obtain study data without participants. From initial design and promotion to communication tactics and patient satisfaction, here are some strategies to ensure success. Advancing pediatric research depends on successful recruitment and retention of study participants. Unfortunately, 9 out of 10 trials end…

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Childhood Kidney Stones: Their Surprising Connection to Future Disease
 Childhood Kidney Stones: Their Surprising Connection to Future Disease 150 150 Jeb Phillips
By: Jeb Phillips

Once thought to be an adult condition, urinary stone disease is increasingly found in children – and may be related to the development of cardiovascular disease, chronic kidney disease and low bone density. By one well-regarded estimate, the risk of developing urinary stone disease…

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