Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases

Learn More

Unraveling the Genetic Mystery Behind a Rare Pediatric Disease

Read More

New National “Vital Signs” to Measure Population-wide Pediatric Health

Find Out More
Close
Enter your
text here
Pregnancy and Ebola: Maternal and Infant Health Outcomes in Ebola Survivors
 Pregnancy and Ebola: Maternal and Infant Health Outcomes in Ebola Survivors 150 150 Abbie Miller
By: Abbie Miller

Ebola virus disease during pregnancy is known to cause fetal demise, and preliminary evidence suggested that pregnancies conceived shortly after recovery from Ebola were also at heightened risk of adverse outcomes. Additionally, the perception that health care providers could contract Ebola from survivors during…

read more
Featured Researcher — Katherine Bline, MD
 Featured Researcher — Katherine Bline, MD 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Katherine Bline, MD, is a critical care medicine physician and principal investigator in the Center for Vaccines and Immunity at Nationwide Children’s Hospital. Experience caring for some of the hospital’s sickest children in the pediatric intensive care unit (PICU) and mentors who pushed her…

read more
What Drives Nephrotic Syndrome Hypercoagulopathy?
 What Drives Nephrotic Syndrome Hypercoagulopathy? 150 150 Mary Bates, PhD
By: Mary Bates, PhD

Antithrombin deficiency does not play a major mechanistic role in the increased clotting risk of nephrotic syndrome, according to a new study. Patients with nephrotic syndrome are at risk for life-threatening venous thromboembolism complications. This risk is thought to be driven by an acquired…

read more
Straightforward Stitch Technique Dramatically Reduces Post-Operative Anorectoplasty Complications
 Straightforward Stitch Technique Dramatically Reduces Post-Operative Anorectoplasty Complications 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

The novel para-U-stitch keeps post-operative wound dehiscence to a minimum, helping patients with anorectal malformations avoid readmission, reoperation and infection. After recognizing a pattern of wound dehiscence and postoperative complications in patients with anorectal malformations (ARMs) repaired without a colostomy bag — meaning they…

read more
Preemptive Stenting of the Left Pulmonary Artery During Surgery for Hypoplastic Left Heart Syndrome
 Preemptive Stenting of the Left Pulmonary Artery During Surgery for Hypoplastic Left Heart Syndrome 150 150 Lauren Dembeck
By: Lauren Dembeck

Perioperative stenting during the comprehensive stage 2 surgery does not negatively impact overall outcomes. However, Preemptive stenting has a survival advantage of babies relative to those who had reactionary stenting.   Each year, approximately 1,000 babies in the United States are born with one…

read more
FDA Approves Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy
 FDA Approves Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy 1024 632 Abbie Miller
By: Abbie Miller

On June 22, 2023, the FDA announced accelerated approval for SRP-9001/ELEVIDYS for Duchenne muscular dystrophy (DMD) following decades of research in the Center for Gene Therapy at Nationwide Children’s Hospital. The FDA approved the treatment for pediatric patients 4-5 years old with DMD. Jerry…

read more
yellow squiggly lines representing chromatin strands in the nucleus
Mapping the 3D Structure of Rhabdomyosarcoma Chromatin
 Mapping the 3D Structure of Rhabdomyosarcoma Chromatin 1024 575 Abbie Miller
By: Abbie Miller

Researchers published the first comprehensive, 3D analysis of the complete rhabdomyosarcoma genome. In a paper published in Nucleic Acids Research Cancer (NAR Cancer), researchers from the Center for Childhood Cancer Research at Nationwide Children’s and their collaborators report a comprehensive 3D chromatin structural analysis…

read more
Exploring Disordered Eating Beyond Binge Eating in Youth with Obesity
 Exploring Disordered Eating Beyond Binge Eating in Youth with Obesity 150 150 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

Youth with obesity can suffer from various disordered eating behaviors beyond binge eating. A holistic approach to caring for these youth can help improve their long-term physical and psychological health outcomes. A literature review recently published in Nutrients shed light on eating disorders beyond…

read more
Ask A Specialist: What Running Distances Are Safe for Children?
 Ask A Specialist: What Running Distances Are Safe for Children? 1024 895 Gabriella Gonzales, MD and James MacDonald, MD, MPH
By: Gabriella Gonzales, MD and James MacDonald, MD, MPH

Sports Medicine experts offer advice for pediatricians about what age it is appropriate for children to run and train for races such as the 5K, 10K, half marathon and marathon. Running is a great activity! It requires very little equipment and can be done…

read more
Targeted Muscle Reinnervation Prevents Neuroma and Phantom Limb Pain in Children After Amputation
 Targeted Muscle Reinnervation Prevents Neuroma and Phantom Limb Pain in Children After Amputation 1024 684 Lauren Dembeck
By: Lauren Dembeck

In certain cases, such as limb traumas and sarcomas, amputation may be chosen to optimize patients’ physical function. Persistent postamputation residual limb or “stump” pain and phantom limb pain can be debilitating and has been associated with prosthetic abandonment in patients who have undergone…

read more
Is Growth Hormone Replacement Safe Following Central Nervous System Tumors?
 Is Growth Hormone Replacement Safe Following Central Nervous System Tumors? 1024 683 Mary Bates, PhD
By: Mary Bates, PhD

Research suggests the benefits of growth hormone therapy outweigh the risks for pediatric cancer survivors. In a new review paper, researchers from Nationwide Children’s Hospital evaluated the risks and benefits associated with administering growth hormone to pediatric patients after diagnosis of a central nervous…

read more
Does Etiology Impact Outcomes After Hemispherectomy?
 Does Etiology Impact Outcomes After Hemispherectomy? 1024 575 Jessica Nye, PhD
By: Jessica Nye, PhD

Patients with cerebral palsy (CP) who have comorbid medically intractable epilepsy (MIE) had similar quantitative functional and seizure outcomes following functional hemispherotomy (FH) or anatomic hemispherectomy (AH), regardless of vascular or dysplastic MIE etiologies.   Early onset seizures are a common comorbidity in CP,…

read more
Baby in NICU
An Alternative Method for Diagnosing Central Adrenal Insufficiency in Newborns
 An Alternative Method for Diagnosing Central Adrenal Insufficiency in Newborns 1024 683 Mary Bates, PhD
By: Mary Bates, PhD

Researchers evaluate the utility of random cortisol levels to diagnose adrenal insufficiency. In infants with central adrenal insufficiency, adrenocorticotropic hormone (ACTH) fails to signal to the adrenal gland, leading to decreased cortisol levels. It is a potentially life-threatening condition requiring urgent diagnosis and treatment.…

read more
conceptual art of DNA
Chaotic Genomes in Childhood Bone Tumors Are Not Always Unstable
 Chaotic Genomes in Childhood Bone Tumors Are Not Always Unstable 1024 575 Jessica Nye, PhD
By: Jessica Nye, PhD

The structural genomic complexity that characterizes most osteosarcoma tumors in children was not evidence of an unstable genome and a driver of cell-to-cell variations in gene expression within each tumor. “We’ve been trying to understand how tumor cells change as they become resistant to…

read more
Creatine Supplements and the Youth Athlete
 Creatine Supplements and the Youth Athlete 945 825 Natalie Wilson
By: Natalie Wilson

Researchers at Nationwide Children’s Hospital found there is insufficient evidence that creatine supplementation is effective for consistently improving athletic performance in adolescents. They also identified a gap in knowledge of the long-term effects of creatine supplementation in this population. Creatine is naturally found in…

read more
Understanding and Implementing the Latest Recommendations for Asthma Management
 Understanding and Implementing the Latest Recommendations for Asthma Management 770 513 Emily Siebenmorgen
By: Emily Siebenmorgen

New guidelines for the care and treatment of asthma in children were released in 2020, but implementation has been slowed by the pandemic and need for education. An estimated 8% of children had asthma in 2020, and it continues to have a significant impact…

read more
Featured Researcher — Jeff Bridge, PhD
 Featured Researcher — Jeff Bridge, PhD 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Jeff Bridge, PhD, director of the Center for Suicide Prevention and Research in the Abigail Wexner Research Institute at Nationwide Children’s Hospital, has been actively working to prevent suicide among at-risk youth since he was 19. Although he started as a volunteer, his career…

read more
ADHD Diagnosis and Management: What Pediatric Providers Need to Know
 ADHD Diagnosis and Management: What Pediatric Providers Need to Know 150 150 Emily Siebenmorgen
By: Emily Siebenmorgen

In a recent episode of PediaCast CME, host Mike Patrick, MD, reviews ADHD diagnosis and management. Attention deficit hyperactivity disorder (ADHD), previously known as attention deficit disorder (ADD), is a relatively common neurodevelopmental disorder. While boys are at least two times more likely to…

read more
5 Questions with Adolfo Etchegaray, MD
 5 Questions with Adolfo Etchegaray, MD 1024 683 Emily Siebenmorgen
By: Emily Siebenmorgen

Meet Adolfo Etchegaray, MD, chief of fetal medicine at Nationwide Children’s Hospital. Learn more about Dr. Etchegaray’s expertise and path to leadership at The Fetal Center, and what lies ahead for this global destination program. Q: What drew you to a career in fetal…

read more
Nurse caring for infant in Neonatal Intensive Care Unit (NICU)
Kidney Support for Babies: Building a Comprehensive and Integrated Neonatal Kidney Support Therapy Program
 Kidney Support for Babies: Building a Comprehensive and Integrated Neonatal Kidney Support Therapy Program 1024 575 Lauren Dembeck
By: Lauren Dembeck

Kidney support therapy (KST), commonly referred to as dialysis, is a life-saving procedure used to manage complications associated with acute kidney injury and kidney failure, such as fluid overload and electrolyte imbalances, or to remove toxins, such as those in patients with inborn errors…

read more