Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases

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Unraveling the Genetic Mystery Behind a Rare Pediatric Disease

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New National “Vital Signs” to Measure Population-wide Pediatric Health

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New Nomogram Helps Optimize 3-D Rotational Angiography for Congenital Cardiac Catheterization
 New Nomogram Helps Optimize 3-D Rotational Angiography for Congenital Cardiac Catheterization 1024 775 Katie Brind'Amour, PhD, MS, CHES
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Clinician-researchers studied a large number of 3-D rotational angiography (3DRA) cases to identify patient and practice factors that produce the highest quality images. In an effort to aid in the successful application of 3-D rotational angiography (3DRA) in cardiac catheterization labs worldwide, a team…

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Bowel Management Program Improves Urinary Symptoms Associated with Pediatric Functional Constipation
 Bowel Management Program Improves Urinary Symptoms Associated with Pediatric Functional Constipation 150 150 JoAnna Pendergrass, DVM
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A one-week bowel management program can significantly improve urinary symptoms in children with functional constipation, possibly eliminating the need for extensive urologic testing. Molly Fuchs, MD, a urologist at Nationwide Children’s Hospital, and her research team recently demonstrated that a bowel management program (BMP)…

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Development of Acute Kidney Injury as a Potential Biomarker of Necrotizing Enterocolitis in Preterm Infants
 Development of Acute Kidney Injury as a Potential Biomarker of Necrotizing Enterocolitis in Preterm Infants 1024 683 Mary Bates, PhD
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Regular measurement of serum creatinine levels could help identify necrotizing enterocolitis sooner. Researchers at Nationwide Children’s neonatal intensive care unit (NICU) evaluated serum creatinine levels and the development of acute kidney injury as a potential biomarker of necrotizing enterocolitis in preterm infants. The retrospective…

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Study Suggests Survivors of Pediatric Brain Tumors Have Altered Connectivity of Key Brain Regions
 Study Suggests Survivors of Pediatric Brain Tumors Have Altered Connectivity of Key Brain Regions 1024 575 Lauren Dembeck
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The findings contribute to a scant body of literature on the changes in functional connection within the brain and neurocognitive outcomes in survivors of pediatric brain tumors. Pediatric brain tumors are the most common solid tumor diagnosis among children in the United States. With…

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Clearing Up Confusion On Cleft Lip and Palate
 Clearing Up Confusion On Cleft Lip and Palate 600 400 Emily Siebenmorgen
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There’s a common misconception that cleft lip and cleft palate is a third-world disease. The truth is: it’s very common in the United States. In fact, it’s the most common birth defect after congenital heart disease, occurring in one in 700 births. That’s around…

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Understanding Eosinophilic Esophagitis
 Understanding Eosinophilic Esophagitis 150 150 Emily Siebenmorgen
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Recent PediaCast CME episode from Mike Patrick, MD, shares important information about diagnosing and treating eosinophilic esophagitis. Eosinophilic esophagitis, or EOE, may not be the first condition providers think of when a patient presents with upper abdominal pain or dysphagia. EOE incidence has increased…

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How Can We Ensure Use of Artificial Intelligence in Pediatric Medicine Is Ethical?
 How Can We Ensure Use of Artificial Intelligence in Pediatric Medicine Is Ethical? 915 341 Jessica Nye, PhD
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Team diversity, data contextual factors, and transparency are key factors for the ethical use of artificial intelligence (AI) in pediatric medicine. AI has been increasingly used in medicine to help clinicians predict patient risk and make treatment decisions. A discussion about the ethical translation…

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Reducing Surgery and Its Associated Risks Through Advanced Interventional Endoscopy
 Reducing Surgery and Its Associated Risks Through Advanced Interventional Endoscopy 150 150 Katie Brind'Amour, PhD, MS, CHES
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Specially trained pediatric endoscopists can perform a range of diagnostic, interventional and therapeutic procedures for children, allowing them to avoid referral to adult endoscopists or even open surgery.   Muhammad Khan, MD, MPH, FASGE, the new director of interventional and diagnostic endoscopy at Nationwide…

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Featured Researcher — Brenda Lilly, PhD
 Featured Researcher — Brenda Lilly, PhD 150 150 Katie Brind'Amour, PhD, MS, CHES
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Brenda Lilly, PhD, a principal investigator in the Center for Cardiovascular Research at Nationwide Children’s Hospital, examines the interactions between endothelial cells, which line the inside of blood vessels, and smooth muscle cells. Blood vessels play a critical role in a wide variety of…

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Celebrating More Than 100 Heart Transplants — And a Host of Other Heart Program Achievements
 Celebrating More Than 100 Heart Transplants — And a Host of Other Heart Program Achievements 1024 746
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Deipanjan Nandi, MD, MSc, shares an update about treating heart failure at Nationwide Children’s Hospital. From transplant to ventricular assist devices and pharmaceutical options, the patient-centered care offers innovative options for patients with heart failure.

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cube made of ball magnets in the palm of a hand
Do Warning Labels on High-Powered Magnets Prevent Child Injury?
 Do Warning Labels on High-Powered Magnets Prevent Child Injury? 1024 521 Laura Dattner
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A recent study suggests parents often don’t notice or read warning labels on high powered magnets. They also perceive these products as children’s toys, despite FDA rules against marketing them to children under age 14 years. High-powered magnet products are made of rare-earth metals,…

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The Heart Center Team Employs New Device to Remove High-Risk Blood Clot
 The Heart Center Team Employs New Device to Remove High-Risk Blood Clot 1024 670 Emily Siebenmorgen
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This first-in-pediatrics procedure was performed by Arash Salavitabar, MD, interventional cardiologist at Nationwide Children’s Hospital.  When a pediatric patient sought care for an accidental gunshot wound to the abdomen, a central line infection during his course at a large regional hospital led to a…

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The New Book on Youth Suicide Prevention
 The New Book on Youth Suicide Prevention 150 150 and
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Our new open access Springer Series book helps close the gap between the latest research in youth suicide prevention and how to make an impact in our communities.  Youth suicide is a public health crisis. It is the second leading cause of death among…

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Examining Pediatric Injury-Related Emergency Department Vistis During the COVID-19 Pandemic
 Examining Pediatric Injury-Related Emergency Department Vistis During the COVID-19 Pandemic 480 320 JoAnna Pendergrass, DVM
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During the first year of the COVID-19 pandemic, the frequency of pediatric injury-related visits to the emergency department decreased, while injury severity increased. The COVID-19 pandemic caused disruptions not only on a global scale but also for individuals, particularly children. Pandemic-related closures of school…

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Significant Weight Gain Observed in Low-Income Youth During the Early COVID-19 Pandemic
 Significant Weight Gain Observed in Low-Income Youth During the Early COVID-19 Pandemic 150 150 JoAnna Pendergrass, DVM
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Low-income youth experienced significant weight gain during the first six months of the COVID-19 pandemic, highlighting the need for simultaneous childhood obesity prevention and treatment.   The COVID-19 pandemic and subsequent mitigation efforts profoundly affected children. Specifically, remote learning and cancellation of extracurricular activities…

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illustrated cross section of islets from pancreas
InSight: Total Pancreatectomy With Islet Autotranplantation: The Basics
 InSight: Total Pancreatectomy With Islet Autotranplantation: The Basics 1024 500 Katie Brind'Amour, PhD, MS, CHES
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Download a PDF version of this image.       This feature was published in the Fall/Winter 2022 print issue. Download the full issue.  Image credit: Mandy Root-Thompson for Nationwide Children’s

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American Academy of Pediatrics Updates Guidelines for the Management of Neonatal Hyperbilirubinemia
 American Academy of Pediatrics Updates Guidelines for the Management of Neonatal Hyperbilirubinemia 1024 737 Emily Siebenmorgen
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Nationwide Children’s physicians collaborate on updates to testing, treatment and follow-up recommendations for preventing hazardous hyperbilirubinemia and possible brain damage. The American Academy of Pediatrics’ (AAP) recommendations for managing hyperbilirubinemia in infants 35 gestational weeks and older are among its most accessed sets of…

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New Initiative Aims to Bring Personalized Diagnosis and Treatment to Children With Solid Tumors
 New Initiative Aims to Bring Personalized Diagnosis and Treatment to Children With Solid Tumors 1024 614 Lauren Dembeck
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Collaboration among National Cancer Institute, Children’s Oncology Group and Nationwide Children’s Hospital will offer molecular characterization of childhood cancers. The National Institutes of Health’s National Cancer Institute (NCI), Children’s Oncology Group (COG), and Nationwide Children’s Hospital are poised to change the direction of pediatric…

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What’s the Relevance of Emotional Intelligence in Medicine?
 What’s the Relevance of Emotional Intelligence in Medicine? 1024 386 Mike Patrick, MD and
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The practice of clinical medicine requires an intelligent mindset. Strong cognitive intelligence (IQ) is required to develop and maintain a substantial knowledge base and to call upon the critical thinking skills needed to synthesize a hundred points of data into a meaningful clinical picture,…

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illustrated cross section of islets from pancreas
TPIAT: A Way Forward for Chronic Pancreatitis
 TPIAT: A Way Forward for Chronic Pancreatitis 1024 500 Katie Brind'Amour, PhD, MS, CHES
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Nationwide Children’s Hospital has assembled a veritable “dream team” of pancreatitis and pediatric transplant surgery experts to offer what they hope will become the world’s preeminent pediatric center for complex pancreatic care. Imagine your child suffering from a sudden, debilitating episode of abdominal pain.…

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