Close
Enter your
text here

Gastroenterology

Calls to Poison Centers About High-Powered Magnets Increased by 444% After Ban Lifts
 Calls to Poison Centers About High-Powered Magnets Increased by 444% After Ban Lifts 1024 521 Laura Dattner
By:
cube made of ball magnets in the palm of a hand

High-powered magnets are small, shiny and made from powerful rare earth metals. Since they started showing up in children’s toys in the early 2000s and then later in desk sets in 2009, high-powered magnets have caused thousands of injuries and are considered to be among the most dangerous ingestion hazards in children. When more than one…

read more
More Data on Rare GI Diseases, With Less Work
 More Data on Rare GI Diseases, With Less Work 1024 535 Katie Brind'Amour, PhD, MS, CHES
By:
Collage of health technology tools

Electronic health record systems can drive knowledge acquisition in rare gastrointestinal conditions — and other orphan diseases — without the burden of duplicative data entry. Rare diseases often remain poorly understood and inefficiently treated due to a lack of objective knowledge on their natural history, pathophysiology or clinical outcomes in response to various therapies. Collecting…

read more
What Puts Adolescent Patients With IBD at Risk for Suboptimal Transitions?
 What Puts Adolescent Patients With IBD at Risk for Suboptimal Transitions? 1024 673 JoAnna Pendergrass, DVM
By:

Psychosocial-related factors, such as mental health diagnoses and public insurance, have been shown to increase the risk of suboptimal transitions in adolescent patients with inflammatory bowel disease. Between ages 18 and 22, adolescent patients transition from pediatric to adult care. Ideally, at the time of transition, patients have the skills to manage their disease and…

read more
Early Intervention is Key to Avoid Hospitalization for Cyclic Vomiting Syndrome
 Early Intervention is Key to Avoid Hospitalization for Cyclic Vomiting Syndrome 1024 683 Mary Bates, PhD
By:
Health care provider talking to male teen patient

Study finds that waiting to go to the emergency department for treatment increases likelihood of hospitalization. Cyclic vomiting syndrome is a functional gastrointestinal disorder characterized by periodic episodes of intense nausea and vomiting lasting hours to days. During episodes, some children become very sick and require emergency department care and hospitalization to manage symptoms and…

read more
Reducing Opioid-Induced Constipation in Patients After Orthopedic Spine Surgery
 Reducing Opioid-Induced Constipation in Patients After Orthopedic Spine Surgery 1024 575 JoAnna Pendergrass, DVM
By:

In pediatric patients undergoing orthopedic spine surgery, a step-wise bowel management plan can effectively reduce opioid-induced constipation and unplanned emergency department visits after surgery. Orthopedic spine surgery can generate pain in the immediate post-surgery period. Opioids are needed to mitigate this pain but commonly cause constipation and other gastrointestinal side effects. Opioid-induced constipation causes abdominal…

read more
Exploring the Use of Complementary and Alternative Medicine in Pediatric Functional Abdominal Pain Disorders
 Exploring the Use of Complementary and Alternative Medicine in Pediatric Functional Abdominal Pain Disorders 1024 680 Mary Bates, PhD
By:
Close up color photo of little boy holding hands on his belly

A survey finds most children with functional abdominal pain disorders use at least one form of complementary and alternative medicine. Functional abdominal pain disorders, which include functional dyspepsia, irritable bowel syndrome and abdominal migraine, are influenced by both biological and psychosocial factors. The underlying mechanisms are complex and largely unknown, making treatment challenging. Researchers from…

read more
Probiotics are Safe and Feasible for Gastrointestinal Symptoms in Autism Spectrum Disorders
 Probiotics are Safe and Feasible for Gastrointestinal Symptoms in Autism Spectrum Disorders 150 150 Mary Bates, PhD
By:

A pilot trial found a trend toward improvements in quality of life in patients treated with probiotics. Gastrointestinal disorders and anxiety symptoms are commonly reported in children with autism spectrum disorder (ASD). Recent research in rodent models and neurotypical humans has demonstrated that changing the gut microbiota can improve gastrointestinal (GI) symptoms. Some studies even…

read more
Advances in Neonatal GERD
 Advances in Neonatal GERD 1024 683 Mary Bates, PhD
By:
Dr. Jadcherla

New studies from the Jadcherla Lab provide insights into diagnosing, classifying and treating GERD in infants. Differentiating gastroesophageal reflux (GER), which is defined as the passage of gastric contents into the esophagus, from GER disease (GERD), when reflux is associated with troubling symptoms, remains a challenge in infants. Symptom-based diagnosis and treatment of GERD has…

read more
Redo Surgery After Anorectal Malformation Repair Can Improve Functional Outcomes
 Redo Surgery After Anorectal Malformation Repair Can Improve Functional Outcomes 1024 575 Mary Bates, PhD
By:

A reoperation can improve continence and quality of life in children still struggling with fecal incontinence following ARM repair. In a new study, researchers from Nationwide Children’s Hospital show that redo surgeries are   safe and may be an effective option for patients with fecal incontinence after an anorectal malformation repair. For many patients, a reoperation…

read more
Exploring the Link Between Cystic Fibrosis and Celiac Disease
 Exploring the Link Between Cystic Fibrosis and Celiac Disease 1024 575 Lauren Dembeck
By:

Overlapping symptoms can cause delayed diagnosis of celiac disease in patients with cystic fibrosis. Physician scientists at Nationwide Children’s Hospital have recently identified three cases of patients with cystic fibrosis, all of whom had the same genotype, were treated with the CFTR modulator, ivacaftor, and were diagnosed with celiac disease. This adds to a novel body…

read more
New Celiac Care Index Improves Adherence to Care Guidelines
 New Celiac Care Index Improves Adherence to Care Guidelines 1024 575 Lauren Dembeck
By:

The recent implementation of a Celiac Care Index (CCI) at Nationwide Children’s Hospital resulted in improved adherence to published care guidelines, reduced variability in baseline evaluations, and indicated potentially unnecessary baseline laboratory tests for further evaluation. The study, which was published in The Journal of Pediatrics, describes the quality improvement (QI) strategy implemented at the hospital.…

read more
Botox Appears Safe for Treatment of Defecation Disorders
 Botox Appears Safe for Treatment of Defecation Disorders 150 150 Kevin Mayhood
By:

Anal botulinum toxin injections (Botox) have increasingly been used in children with functional anorectal and colonic disorders during the past 15 years. A study at Nationwide Children’s Hospital, combined with a review of published literature, shows this off-label use of Botox is safe and complications are rare. Complications occurred in less than 0.7% of 1332…

read more
Rethinking Gastroesophageal Reflux Disease (GERD) in Infants
 Rethinking Gastroesophageal Reflux Disease (GERD) in Infants 150 150 Lauren Dembeck
By:

Novel use of existing technology points to other causes of GERD-like symptoms. While typically attributed to gastroesophageal reflux disease (GERD), supra-esophageal symptoms, such as cough, back arching and gagging, can be temporally associated with aerophagia, according to a new study by researchers at Nationwide Children’s Hospital. The findings come from the novel implementation of standard…

read more
Type of Anorectal Malformation at Birth is Predictive of Fecal Continence
 Type of Anorectal Malformation at Birth is Predictive of Fecal Continence 150 150 Kevin Mayhood
By:

Study also finds fecal continence rates for children born with ARMs are lower than previously reported. Recently published research shows the rate of fecal continence among 4-year-olds who underwent surgery for an anorectal malformation (ARM) as infants averages 40%, and the type of malformation — which reflects severity — is predictive of the outcome. Though…

read more
A New Therapeutic Era in Pediatric Functional and Motility Disorders
 A New Therapeutic Era in Pediatric Functional and Motility Disorders 150 150 Katie Brind'Amour, PhD, MS, CHES
By:

20 years ago, treatment options were limited for children with functional gastrointestinal (GI) and motility disorders. Now, a growing list of drugs, behavioral and dietary care plans, and an advanced, forward-looking technique – neuromodulation – are transforming pediatric GI care. Gastrointestinal (GI) disorders are notoriously difficult to diagnose. Virtually all functional and motility-related GI problems…

read more
Development of a Patient Reported Experience and Outcomes Measure in Pediatric Patients
 Development of a Patient Reported Experience and Outcomes Measure in Pediatric Patients 150 150 Lauren Dembeck
By:

Researchers develop a questionnaire that enables them to assess the burden of treatment compared to the burden of the disease. Researchers have developed a rigorous, patient reported experience and outcomes questionnaire for pediatric patients undergoing an intensive bowel management program (BMP). The report was published online in the Journal of Pediatric Gastroenterology and Nutrition. “Often physicians…

read more
How Similar Is Chronic Pancreatitis Among Pediatric and Adult Patients?
 How Similar Is Chronic Pancreatitis Among Pediatric and Adult Patients? 150 150 Lauren Dembeck
By:

A large, international study highlights room for improvement in care and transition of patients ages 17 to 24 years old. A new study that compared adult patients with pancreatic disease starting when they were children with pediatric patients with pancreatic disease revealed remarkable similarities in the cause of the disease and progression to chronic pancreatitis.…

read more
Worth It: Why Wrestling Through the Logistical Challenges of a Multidisciplinary Colorectal Center Matters
 Worth It: Why Wrestling Through the Logistical Challenges of a Multidisciplinary Colorectal Center Matters 150 150 Jeb Phillips
By:

Consider the complex case of a girl born with rectal, vaginal and urinary tracts fused into a common channel – a cloacal malformation. The child needs reconstructive procedures across three different organ systems and three different surgical specialties. It could take months or years to manage the surgeries needed for the colorectal portion, then the…

read more
Chronic Constipation: What Manometry Tells Us About Gastro-Colonic Response and Pathophysiology
 Chronic Constipation: What Manometry Tells Us About Gastro-Colonic Response and Pathophysiology 150 150 Katie Brind'Amour, PhD, MS, CHES
By:
Saving Constipation Treatment Costs With a Bowel Management Program
 Saving Constipation Treatment Costs With a Bowel Management Program 1024 575 Jeb Phillips
By:
Simple illustrated diagram of the GI track with organs colorized and body outline and background in blue

A protocolized approach significantly reduced ED visits and hospital admissions for children with chronic constipation – and became a driver for surgical referrals. If hospitals are willing to foot the bill for staffing and start-up costs, a structured bowel management program for children with chronic severe constipation likely saves both individual and institutional health care…

read more
Race, Insurance, and ED Visits for Pediatric Crohn’s Disease
 Race, Insurance, and ED Visits for Pediatric Crohn’s Disease 1024 680 Jeb Phillips
By:
Close up color photo of little boy holding hands on his belly

Black children and children insured by Medicaid make more repeat emergency department visits for Crohn’s disease than their white and privately insured peers. In what appears to be the first nationally representative study evaluating the impact of race and insurance status on emergency department treatment for Crohn’s disease, a team of physicians and researchers at…

read more
New Guidelines Offer Practical Tools to Treat GI Reflux
 New Guidelines Offer Practical Tools to Treat GI Reflux 150 150 Jeb Phillips
By:

An international committee’s new recommendations reflect shifting opinions about acid-suppressive medications and include an expanded diagnostic algorithm. While reflux-related complaints are heard often by pediatric gastroenterologists and primary care physicians, it can be difficult to tell when gastroesophageal reflux (GER) crosses the line into gastroesophageal reflux disease (GERD) — or how that disease should be…

read more
Quality Improvement Boosts Use of Enteral Therapy in Patients With Crohn’s Disease
 Quality Improvement Boosts Use of Enteral Therapy in Patients With Crohn’s Disease 1024 575 Kevin Mayhood
By:
Color image of enteral complete liquid nutritional products of several brands

Refined procedures, tools and support promote this proven alternative to steroids. A team of researchers found that employing quality-improvement methods increased use of exclusive enteral nutrition (EEN) to induce remission in children with Crohn’s disease at Nationwide Children’s Hospital. By increasing awareness of the therapy, standardizing procedures and providing support, EEN usage increased from less…

read more
Children With Autism and Abdominal Pain Have Distinctive Bacterial Profiles
 Children With Autism and Abdominal Pain Have Distinctive Bacterial Profiles 150 150 Kevin Mayhood
By:

The microbiome may harbor causes of abdominal and behavioral issues and potential targets for relief. Children with autism spectrum disorder (ASD) and functional abdominal pain may have a distinct microbiome-neuroimmune profile compared to kids with gastrointestinal disorders (GI) and those with no GI illness. Building on others’ research showing that Clostridia bacteria in the gut are altered…

read more
How to Solve Feeding Disorders Without a G-Tube
 How to Solve Feeding Disorders Without a G-Tube 1024 575 Jeb Phillips
By:

Babies in a neonatal intensive care unit must have a safe way of receiving nutrition in order to go home. Full oral feeding is ideal, of course. But for those patients with persistent difficulty feeding by mouth, there were two primary options before 2002 to guarantee nutrients by the time of discharge. Both had their…

read more
Diagnosing GERD in Neonates? Be Cautious
 Diagnosing GERD in Neonates? Be Cautious 150 150 Jeb Phillips
By:

Gastroesophageal reflux disease is likely over-diagnosed in neonates, leading to unnecessary and harmful treatment. Approximately 10 percent of infants born preterm in the United States are diagnosed with gastroesophageal reflux disease (GERD). But it’s almost certain that not all of those babies actually have GERD, say neonatologists at Nationwide Children’s Hospital. The probable over diagnosis leads to…

read more
One Dose Probiotic Biofilm Protects Against NEC
 One Dose Probiotic Biofilm Protects Against NEC 150 150 Kevin Mayhood
By:

Probiotic biofilm enables the beneficial bacteria to withstand stomach acid, promote microbial activity and decrease intestinal inflammation. A single dose of a probiotic biofilm grown on microspheres prevented or significantly reduced the severity of necrotizing enterocolitis (NEC) in animal models of the disease, researchers show. This delivery method not only appears to protect against NEC…

read more
When Should Kids With Severe Functional Constipation Have Surgery?
 When Should Kids With Severe Functional Constipation Have Surgery? 150 150 Jeb Phillips
By:

A protocol developed by pediatric surgeons and gastroenterologists allows patients to receive specific surgical interventions that will be most beneficial – and allows many patients originally referred for surgery to avoid it altogether. Children with severe functional constipation are most often referred for surgery after failure of medical management. But there’s a problem with this…

read more
InSight: Restoring Normal Habits
 InSight: Restoring Normal Habits 471 285 Tiasha Letostak, PhD
By:

SACRAL NERVE STIMULATION (SNS) is a new treatment that helps control urinary incontinence and fecal soiling. For some children, the nerves that control urination and bowel movements do not work correctly. The SNS unit consists of a small, safe battery and wire under the skin and sends signals to the sacral nerve. The signals help restore…

read more
Enteral Therapy Thursday: Professionals Sharing the Patient Experience
 Enteral Therapy Thursday: Professionals Sharing the Patient Experience 150 150 Jennifer Smith, MS, RD, CSP, LD, LMT
By:

A multidisciplinary team puts themselves on enteral nutrition for a day to gain insights into the patient experience. Enteral nutrition for Crohn’s disease is a well-established practice using liquid formulas to treat Crohn’s disease.  Patients who choose this form of treatment either drink the prescribed amount of formula or receive the formula via a feeding…

read more
Colorectal Cancer Screening and the Pediatric Subspecialist
 Colorectal Cancer Screening and the Pediatric Subspecialist 150 150 Katie Brind'Amour, PhD, MS, CHES
By:

Screening a 15-year-old for pre-cancerous polyps may seem a bit unusual, as colon cancer is widely considered an adult disease. But for children with a family history of Lynch syndrome, a hereditary condition that increases the risk of colon and other cancers, life-threatening malignancies can develop as early as the mid-teens. Fewer than one in…

read more
Delays and Difficulties: Fecal Microbiota Transplants as Therapy
 Delays and Difficulties: Fecal Microbiota Transplants as Therapy 150 150 Katie Brind'Amour, PhD, MS, CHES
By:

Use of fecal microbiota transplantation to treat a wide range of disorders is in limbo while the FDA decides how to regulate the therapy. Between 1997 and 2007, Clostridium difficile bacterial infections among U.S. children more than doubled and its mortality rate among all U.S. cases more than quadrupled. Clinicians are turning to a number of treatment…

read more
Using Zinc for Growth Delays in Babies Born Preterm
 Using Zinc for Growth Delays in Babies Born Preterm 150 150 Katie Brind'Amour, PhD, MS, CHES
By:

Zinc supplementation in extremely low birth-weight (ELBW) infants with chronic lung disease improves weight gain and linear growth, according to a retrospective study performed at Nationwide Children’s Hospital. The study is one of the first to look at the association between zinc supplementation and growth in ELBW babies with chronic lung disease, also known as bronchopulmonary dysplasia.…

read more