Biofilms: The Good, the Bad & the Groundbreaking

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From Scan to Plan: Making Virtual Surgical Planning the Standard of Care for Ortho-oncology Operations

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When Talking About Birth Control, Don’t Leave Boys Out of the Conversation
 When Talking About Birth Control, Don’t Leave Boys Out of the Conversation 150 150 Sarah Saxbe, MS, MSW, LISW-S
By: Sarah Saxbe, MS, MSW, LISW-S

Sex education for boys should include information about all forms of birth control, even those for females. When a child arrives in his or her pediatrician’s office each year for their well visit, the nurse and provider often go over a long list of…

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The First Study of Oncolytic HSV-1 in Children and Young Adults With Cancer Indicates Safety and Tolerability
 The First Study of Oncolytic HSV-1 in Children and Young Adults With Cancer Indicates Safety and Tolerability 1024 575 Abbie Miller
By: Abbie Miller

The phase 1 trial shows safety and tolerance of HSV1716 in the pediatric population; evidence of viral replication in the blood and acute inflammation on PET/CT scans suggest a phase 2 trial for dosage and efficacy is warranted. HSV1716 – an oncolytic herpes simplex…

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Secondary Findings: What Should Be Reported?
 Secondary Findings: What Should Be Reported? 150 150 Brianne Moore
By: Brianne Moore

With the growing use of exome and genome sequencing in research and diagnosis, the ACMG has recently released a policy update on the reporting of secondary findings. Genomic sequencing is instrumental in identifying many diseases. It can also reveal disease causing variants in our…

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In Extremely Preterm Babies, SNAP-II Score Predicts Brain Impairments at Age 10
 In Extremely Preterm Babies, SNAP-II Score Predicts Brain Impairments at Age 10 150 150 Kevin Mayhood
By: Kevin Mayhood

Measures taken in first 12 hours of life are associated with a host of deficits. Children born extremely preterm are known to be at increased risk of neurodevelopmental impairments, but not all babies born the same early date and weight are equal. Researchers have…

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The Maternal Microbiome: How Stress During Pregnancy Impacts Female Offspring in Adulthood
 The Maternal Microbiome: How Stress During Pregnancy Impacts Female Offspring in Adulthood 150 150 Tiasha Letostak, PhD
By: Tiasha Letostak, PhD

A recent study suggests a critical window of pregnancy where stress is able to influence the microbiome and intrauterine environment, with lasting behavioral consequences. Previous research has demonstrated that stress during pregnancy changes the composition of the intestinal microbiota and is related to the…

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Balancing Immune Activation and Suppression After Cardiopulmonary Bypass
 Balancing Immune Activation and Suppression After Cardiopulmonary Bypass 150 150 Mary Bates, PhD
By: Mary Bates, PhD

Understanding how the immune system responds to CPB could dramatically impact postsurgical outcomes. Cardiopulmonary bypass (CPB) is a relatively routine procedure, generally with favorable outcomes. However, among the risks posed to patients is the over- or under-activation of the immune system following the surgery.…

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Bracing for Buckle Fractures
 Bracing for Buckle Fractures 150 150 Jeb Phillips
By: Jeb Phillips

Shifting from casts to splints for distal radius buckle fractures has saved time and money for providers and families. The traditional treatment for distal radius buckle fractures involves immobilization in a short- or longarm cast. A 2015 multi-institutional study found that more than 70…

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Does Celiac Disease Increase Risk for Functional Abdominal Pain Disorders?
 Does Celiac Disease Increase Risk for Functional Abdominal Pain Disorders? 150 150 Tiasha Letostak, PhD
By: Tiasha Letostak, PhD

About the authorAuthorArticles by the Author Tiasha Letostak, PhDTiasha is the senior strategist for Clinical & Research Communications at Nationwide Children's Hospital. She provides assistance to investigators in The Research Institute and clinician-scientists at Nationwide Children’s for internal and external communication of clinical studies,…

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Survey: Physical Barriers, Not Fear, Keep Homeless Youth From Receiving Care
 Survey: Physical Barriers, Not Fear, Keep Homeless Youth From Receiving Care 150 150 Brianne Moore
By: Brianne Moore

Research survey investigates barriers to care in unstably-housed youth. Every year, an estimated 1.6 to 1.7 million youth in the United States are living on the streets, in shelters or in other temporary living situations. Earlier studies have suggested that homeless youth do not…

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In Sight: Three Procedures, One Surgery
 In Sight: Three Procedures, One Surgery 388 320 Jeb Phillips
By: Jeb Phillips

Colorectal Surgery, Urology and Gynecology coordinate to save tissue and time. A child with a complex colorectal and pelvic condition may require several surgeries over months or years before they are able to successfully manage their urine and stool. With advance planning and coordination…

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image of heart with fontan conduit highlighted
A Narrow Focus: Perfecting Tissue Engineered Vascular Grafts
 A Narrow Focus: Perfecting Tissue Engineered Vascular Grafts 1024 575 Abbie Miller
By: Abbie Miller

A pair of surgeon-researchers is perfecting tissue engineered vascular grafts through bench, clinical and computational modeling studies.

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Intervention for Medically Complex Children Improves Health, Saves Money
 Intervention for Medically Complex Children Improves Health, Saves Money 800 533 Kevin Mayhood
By: Kevin Mayhood

The population-based program features coordinated care, education and feeding tube management. A population-based intervention for children with medical complexity in central and southeast Ohio led to fewer admissions, shorter hospital stays and a reduction of inpatient charges of nearly $11.8 million over 30 months,…

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The Equity Equation
 The Equity Equation 1024 575 Deena Chisolm, PhD
By: Deena Chisolm, PhD

Deena J. Chisolm, PhD, director of the Center for Population Health and Equity Research at Nationwide Children’s Hospital, applies a health equity approach to improving infant mortality outcomes. Health care quality and outcomes differ by race, ethnicity, wealth and place of residence. In fact,…

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Discovery to Drug Development: Expanding the Role of Academic Centers
 Discovery to Drug Development: Expanding the Role of Academic Centers 1024 575 Abbie Miller
By: Abbie Miller

As more researchers at academic centers become involved in drug development, institutions are responding with support and guidance. Researchers at academic institutions regularly make discoveries about disease processes and potential therapeutic agents. Translational medicine is focused on moving these discoveries out of the laboratory…

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How to Solve Feeding Disorders Without a G-Tube
 How to Solve Feeding Disorders Without a G-Tube 1024 575 Jeb Phillips
By: Jeb Phillips

Babies in a neonatal intensive care unit must have a safe way of receiving nutrition in order to go home. Full oral feeding is ideal, of course. But for those patients with persistent difficulty feeding by mouth, there were two primary options before 2002…

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Best Practices in Severe BPD Treatment
 Best Practices in Severe BPD Treatment 150 150 Jeb Phillips
By: Jeb Phillips

To help standardize care, the Bronchopulmonary Dysplasia Collaborative has published a comprehensive review of evidence-based approaches for treatment of patients with severe forms of the disease. Infants with severe bronchopulmonary dysplasia (BPD) have high risks of late morbidities and mortality, but the best ways…

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Cognitive Behavioral Therapy Can Help Children With Persistent Post-Concussive Symptoms
 Cognitive Behavioral Therapy Can Help Children With Persistent Post-Concussive Symptoms 150 150 Mary Bates, PhD
By: Mary Bates, PhD

A psychological intervention improves kids’ function and quality of life even years after a concussion. For most children and adolescents that experience concussions, symptoms resolve after a week or two. However, a small subset of kids has persistent symptoms lasting for months or even…

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How a QI Intervention Lowered Breast Milk Errors in a Busy NICU
 How a QI Intervention Lowered Breast Milk Errors in a Busy NICU 150 150 Kevin Mayhood
By: Kevin Mayhood

Bedside barcode scanners and dedicated milk preparation technicians helped drive the decline. A quality improvement (QI) initiative in the Neonatal Intensive Care Unit (NICU) at Nationwide Children’s Hospital has been associated with a substantial reduction in errors administering mother’s milk to these vulnerable infants.…

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How to Reduce ED Visits and Hospital Admissions for Patients With Epilepsy
 How to Reduce ED Visits and Hospital Admissions for Patients With Epilepsy 150 150 Jeb Phillips
By: Jeb Phillips

About the authorAuthorArticles by the Author Jeb PhillipsJeb is the Managing Editor, Executive Communications, in the Department of Marketing and Public Relations at Nationwide Children's Hospital. He contributes feature stories and research news to PediatricsOnline, the hospital’s electronic newsletter for physicians and other health…

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Human Trafficking: How many victims have you treated?
 Human Trafficking: How many victims have you treated? 1024 575 Abbie Miller
By: Abbie Miller

Data shows that health care providers may be coming into contact with victims and those at risk with more frequency than expected. How many victims have you treated? The answer is probably higher than you think. According to a report published in the Annals of…

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