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Toward a Cell-based Therapy for Cystic Fibrosis Lung Disease
 Toward a Cell-based Therapy for Cystic Fibrosis Lung Disease 150 150 Jeb Phillips
By: Jeb Phillips

Because cystic fibrosis (CF) is a genetic disease caused by mutations in the CFTR gene, the pulmonary disease could be reversed if CF airway epithelial cells were replaced with basal cells expressing CFTR without mutations. That is one of the ideas underpinning the Cystic Fibrosis…

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Pediatric Patients Receive Higher Radiation at Non-pediatric Trauma Centers
 Pediatric Patients Receive Higher Radiation at Non-pediatric Trauma Centers 150 150 Bailey Dye
By: Bailey Dye

A novel software tool for calculating radiation burden has determined that pediatric trauma patients, evaluated using CT imaging primarily at adult trauma centers, demonstrate higher radiation exposure than those imaged primarily at a pediatric trauma center. Computed tomography (CT) is a mainstay of the…

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Can Brain Imaging Help Predict Bipolar Disorder in High Risk Children?
 Can Brain Imaging Help Predict Bipolar Disorder in High Risk Children? 150 150 Mary Bates, PhD
By: Mary Bates, PhD

Patterns in connectivity in a portion of the frontal lobe called the inferior frontal gyrus appears to be an early biomarker in children of parents with bipolar disorder. Researchers report a potential neural marker of individual risk in those with a family history of…

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Novel Metric Predicts Severity of Community-Acquired Pneumonia
 Novel Metric Predicts Severity of Community-Acquired Pneumonia 150 150 Rachael Hardison
By: Rachael Hardison

Researchers utilize a biomarker to predict disease severity during early stages of pneumonia. Community-acquired pneumonia (CAP) is a leading cause of hospitalization and mortality in children. Each year, 4 percent of children under 5 years of age will develop CAP in industrialized countries. Although…

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Hey Google, Siri and Alexa, How Do We Bring Voice Technology Into Health Care?
 Hey Google, Siri and Alexa, How Do We Bring Voice Technology Into Health Care? 1024 576 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

As voice assistant technology plays an increasing role in everything from home security to baking, researchers at the vanguard of medical innovation must figure out how to appropriately adapt it for the future of health care. Voice assistant technology has advanced dramatically in the…

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“Learn From Every Patient” to Improve Clinical Care
 “Learn From Every Patient” to Improve Clinical Care 150 150 Lauren Dembeck
By: Lauren Dembeck

How can busy clinicians tending to clinical care simultaneously conduct translational research and improve treatments for patients? The Nationwide Children’s Hospital Cerebral Palsy team recently reported an evidence-based change in practice — eliminating annual screening X-rays in patients mildly affected by CP — facilitated…

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Collaboration Key in Recent Advances for Batten Disease
 Collaboration Key in Recent Advances for Batten Disease 1024 683 Abbie Miller
By: Abbie Miller

Batten disease (neuronal ceroid lipofuscinosis) is a collection of lysosomal storage disorders caused by a variety of genetic mutations. These disorders cause an accumulation of cellular “trash” to build up, ultimately causing the neurons to die. So far, scientists have identified 13 different versions of…

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What Pediatric Care Providers Need to Know About Kratom
 What Pediatric Care Providers Need to Know About Kratom 150 150 Laura Dattner
By: Laura Dattner

The herbal supplement is increasingly the source of toxic exposures and health care facility admissions. In recent years, kratom has become popular as a treatment for chronic or acute pain as well as mood conditions such as depression and anxiety. It is also sometimes…

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Acid Reflux Index Severity Alone Should Not Determine GERD Diagnosis
 Acid Reflux Index Severity Alone Should Not Determine GERD Diagnosis 150 150 Kevin Mayhood
By: Kevin Mayhood

ARI severity plays little role in symptom generation, but symptoms alone are unreliable for diagnosing gastroesophageal reflux disease, researchers say. However, a new study from the Neonatal and Infant Feeding Disorders Program at Nationwide Children’s Hospital shows that stomach acid alone doesn’t appear to have much…

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Vaccine Enables Model to Clear Hepatitis C Virus and Prevent Persistence
 Vaccine Enables Model to Clear Hepatitis C Virus and Prevent Persistence 150 150 Kevin Mayhood
By: Kevin Mayhood

Scientists are conceptualizing an effective HCV vaccine using a new animal model. Hepatitis C virus (HCV) subverts responses of immune cells, resulting in chronic infection in more than 71 million people worldwide. The virus causes 1.79 million new infections and 399,000 deaths worldwide annually.…

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Keeping Young Patients With Congenital Heart Disease Connected to Care
 Keeping Young Patients With Congenital Heart Disease Connected to Care 150 150 Mary Bates, PhD
By: Mary Bates, PhD

Race, type of insurance and severity of disease affect likelihood of experiencing a lapse in care for CHD patients younger than 5 years. Lapse in care is prevalent among congenital heart disease survivors by age five, with nonwhites demonstrating elevated risk, according to a…

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Improving Care for Adolescents and Young Women With Pelvic Pain: Highlights From New ACOG Guidelines
 Improving Care for Adolescents and Young Women With Pelvic Pain: Highlights From New ACOG Guidelines 1024 683 Geri Hewitt, MD
By: Geri Hewitt, MD

Between 50 and 90 percent of adolescents and young women report dysmenorrhea- and endometriosis-related pelvic pain. Pediatricians and primary care doctors have many opportunities to recognize and treat these conditions, leading to enhanced quality of life and better long-term reproductive outcomes for these patients.…

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A Simple Measure to Help Early Detection of Hemiplegic Cerebral Palsy in Infants
 A Simple Measure to Help Early Detection of Hemiplegic Cerebral Palsy in Infants 150 150 Jeb Phillips
By: Jeb Phillips

An easily derived Hammersmith Infant Neurological Examination asymmetry score, in combination with the total HINE score, differentiates typically developing infants from those with hemiplegic CP. While cerebral palsy can now be diagnosed at 6 months of age – allowing for earlier interventions and better…

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National Survey of Emergency Department Management of Self-Harm Highlights Successes, Room for Improvement
 National Survey of Emergency Department Management of Self-Harm Highlights Successes, Room for Improvement 150 150 Abbie Miller
By: Abbie Miller

Only 15 percent of hospitals surveyed routinely provided all recommended safety planning elements. Approximately half a million patients in the United States arrive in emergency departments (EDs) after deliberate self-harm annually. In the short term following the ED visit, these patients are at high…

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Simple Tip for Elbow Pinning: Adjust Your Wire Size
 Simple Tip for Elbow Pinning: Adjust Your Wire Size 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

About the authorAuthorArticles by the Author Katie Brind'Amour, PhD, MS, CHESKatherine (Katie) Brind’Amour is a freelance medical and health science writer based in Pennsylvania. She has written about nearly every therapeutic area for patients, doctors and the general public. Dr. Brind’Amour specializes in health…

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Clinical Trial Open for Patients With Limb-Girdle Muscular Dystrophy Type 2E
 Clinical Trial Open for Patients With Limb-Girdle Muscular Dystrophy Type 2E 150 150 Abbie Miller
By: Abbie Miller

About the authorAuthorArticles by the Author Abbie MillerAbbie (Roth) Miller, MS, MWC, is a passionate communicator of science. As the manager of medical and science content at Nationwide Children’s Hospital, she shares stories about innovative research and discovery with audiences ranging from parents to…

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Growth Hormone Also Has Metabolic Benefits
 Growth Hormone Also Has Metabolic Benefits 150 150 Mary Bates, PhD
By: Mary Bates, PhD

About the authorAuthorArticles by the Author Mary Bates, PhDMary a freelance science writer and blogger based in Boston. Her favorite topics include biology, psychology, neuroscience, ecology, and animal behavior. She has a BA in Biology-Psychology with a minor in English from Skidmore College in…

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A Multimodal Treatment Approach Produces Excellent Outcomes in Pediatric Paget-Schroetter Syndrome
 A Multimodal Treatment Approach Produces Excellent Outcomes in Pediatric Paget-Schroetter Syndrome 150 150 Jeb Phillips
By: Jeb Phillips

About the authorAuthorArticles by the Author Jeb PhillipsJeb is the Managing Editor, Executive Communications, in the Department of Marketing and Public Relations at Nationwide Children's Hospital. He contributes feature stories and research news to PediatricsOnline, the hospital’s electronic newsletter for physicians and other health…

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Do All Cystic Fibrosis Modulators Improve Killing of Bacteria?
 Do All Cystic Fibrosis Modulators Improve Killing of Bacteria? 150 150 Lauren Dembeck
By: Lauren Dembeck

About the authorAuthorArticles by the Author Lauren DembeckLauren Dembeck, PhD, is a freelance science and medical writer based in New York City. She completed her BS in biology and BA in foreign languages at West Virginia University. Dr. Dembeck studied the genetic basis of…

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Study Provides New Clinical Evidence That Avoids Painful Tests for Infants With Fever
 Study Provides New Clinical Evidence That Avoids Painful Tests for Infants With Fever 150 150 Nationwide Children's
By: Nationwide Children's