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Single Ventricle

Study Reveals Challenges in Cardiac Transplantation Referrals for High-Risk Infants
 Study Reveals Challenges in Cardiac Transplantation Referrals for High-Risk Infants 1024 670 JoAnna Pendergrass, DVM
By: JoAnna Pendergrass, DVM

Findings from a recent retrospective study demonstrate challenges and inequities in cardiac transplantation referrals for infants with single ventricle congenital heart disease, suggesting the need to improve access to transplantation and the timing and rate of transplantation referral.   A retrospective study led by Lydia K. Wright, MD, pediatric cardiologist at Nationwide Children’s Hospital, examined…

Don’t Oversize Your Tissue-Engineered Vascular Grafts: Insights for the Translation of New Surgical Technologies
 Don’t Oversize Your Tissue-Engineered Vascular Grafts: Insights for the Translation of New Surgical Technologies 1024 683 Abbie Miller
By: Abbie Miller
Close-up of gloved hands passing the surgical scissors, operating room, hospital

Study shows that adoption of a tissue engineered vascular graft technology currently in clinical trials would require a shift in surgical approach. Tissue engineered vascular grafts (TEVGs) are designed to overcome two important problems associated with synthetic conduits used in surgeries for children with congenital heart disease (CHD): the lack of growth potential and the…

Single Ventricle, Many Research Angles
 Single Ventricle, Many Research Angles 1024 658 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

An overview of the people and projects behind one of the world’s most robust single-ventricle heart disease research hubs.  In the field of single-ventricle heart disease (SVHD), there are more questions than answers. What causes the heart to form with only one ventricle? At what point in fetal development might we intervene to improve its…

Preemptive Stenting of the Left Pulmonary Artery During Surgery for Hypoplastic Left Heart Syndrome
 Preemptive Stenting of the Left Pulmonary Artery During Surgery for Hypoplastic Left Heart Syndrome 150 150 Lauren Dembeck
By: Lauren Dembeck

Perioperative stenting during the comprehensive stage 2 surgery does not negatively impact overall outcomes. However, Preemptive stenting has a survival advantage of babies relative to those who had reactionary stenting.   Each year, approximately 1,000 babies in the United States are born with one of the most common critical congenital heart defects—hypoplastic left heart syndrome.…