Heart

How Patient-Derived Stem Cells are Changing the Trajectory of Congenital Heart Disease Research
How Patient-Derived Stem Cells are Changing the Trajectory of Congenital Heart Disease Research 1024 683 Katie Brind'Amour, PhD, MS, CHES

Small blood samples — and the patient-specific, induced pluripotent stem cells (iPSCs) they enable — turn into valuable research material for understanding congenital cardiovascular disorders, especially when united with modern genome sequencing and editing, animal models and three dimensional tissue growth technologies. Patient-derived induced pluripotent stem cells (iPSCs) have a significant downside for studying most…

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Stent Implantations Are an Option for Small Patients
Stent Implantations Are an Option for Small Patients 1024 670 Mary Bates, PhD

Stents that can be dilated to adult size are safe and effective for the treatment of coarctation of the aorta in young patients. Studies have demonstrated stent implantation is more effective and safer than balloon angioplasty for the treatment of coarctation of the aorta in adult and older pediatric patients. In smaller patients, however, particularly…

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