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In Brief

Keeping Kids in Treatment for Opioid Use Disorder
 Keeping Kids in Treatment for Opioid Use Disorder 1024 683 Mary Bates, PhD
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A multifaceted quality improvement program increases patient retention in addiction treatment. Adolescents and young adults with opioid use disorder often struggle to stay in treatment that’s not designed for people at their developmental stage. The Medication-Assisted Treatment of Addiction (MATA) Program at Nationwide Children’s Hospital is one of the only pediatric providers for adolescents with opioid use…

Study Sheds Light on Causes of Phenotype Variation in IQSEC2-Related Disease
 Study Sheds Light on Causes of Phenotype Variation in IQSEC2-Related Disease 1024 575 Lauren Dembeck
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Variant type and inheritance pattern affect patient phenotypes in IQSEC2-related disease. Investigators from Nationwide Children’s Hospital and The Ohio State University College of Medicine recently identified additional pathogenic variants within the IQSEC2 gene, which has previously been associated with X-linked intellectual disability, in five patients. They also demonstrated that different variant types correlate with the severity of…

Unlocking the Structure of Biofilms
 Unlocking the Structure of Biofilms 1024 575 Kevin Mayhood
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Illustration showing the precise pattern of a biofilm - a perfect, 3D matrix

Researchers characterize a component that stabilizes biofilms, a step toward learning ways to disrupt protection of harmful bacteria. In the extracellular DNA lattice of bacterial biofilms, nature appears to reprise the functional equivalent of Holliday junction (HJ) intermediates — cross-shaped structures formed during the process of genetic recombination, researchers at Nationwide Children’s Hospital report in Proceedings…

Better Bone Healing by Reversing Current Techniques?
 Better Bone Healing by Reversing Current Techniques? 1024 575 Katie Brind'Amour, PhD, MS, CHES
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Bones may heal denser and stronger when given room for controlled micro-movement at first, followed by rigid stabilization — a complete flip-flop of the standard of care. A combination of biology and mechanical influence determines how well a bone heals, for better or worse. For half a century, physicians have believed that complete bone immobilization…

Health Care and Medication Use Among Adolescents with Opioid Use Disorder in Ohio
 Health Care and Medication Use Among Adolescents with Opioid Use Disorder in Ohio 1024 575 Abbie Miller
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From Ohio – a state in the heart of the opioid crisis – a new study on the medications prescribed to teens with opioid use disorder. A new study from researchers in the Center for Innovation in Pediatric Practice at the Abigail Wexner Research Institute at Nationwide Children’s Hospital, recently published in Journal of Adolescent Health,…

Study Shows Promising Host-Targeted Approach for the Prevention and Cure of Gonorrhoea in Women
 Study Shows Promising Host-Targeted Approach for the Prevention and Cure of Gonorrhoea in Women 1024 683 Nationwide Children's
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In research published in mBio, researchers from the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital and Griffith University’s Institute for Glycomics have discovered non-antibiotic (host-targeted) therapies for the effective treatment of Neisseria gonorrhoeae infections by repurposing existing drugs. Gonorrhoea is the second most commonly reported sexually transmitted infection (STI). The Centers for Disease Control and…

A Natural History of Duchenne Muscular Dystrophy in Boys 3 to 6 Years Old
 A Natural History of Duchenne Muscular Dystrophy in Boys 3 to 6 Years Old 1024 575 Abbie Miller
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boy with muscular dystrophy completing walk test

A prospective, multicenter study following 153 boys younger than 6 years old documents disease progression of Duchenne muscular dystrophy. Duchenne muscular dystrophy is the most common inherited neuromuscular disorder that affects all races and ethnicities. It affects males, occurring in 1/3,600 live-born infant boys. While some affected newborns may have mild hypotonia, other symptoms are rarely…

New Celiac Care Index Improves Adherence to Care Guidelines
 New Celiac Care Index Improves Adherence to Care Guidelines 1024 575 Lauren Dembeck
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The recent implementation of a Celiac Care Index (CCI) at Nationwide Children’s Hospital resulted in improved adherence to published care guidelines, reduced variability in baseline evaluations, and indicated potentially unnecessary baseline laboratory tests for further evaluation. The study, which was published in The Journal of Pediatrics, describes the quality improvement (QI) strategy implemented at the hospital.…

New Application of Nuclear Imaging in the Legs May Enable Early Detection of Cardiovascular Problems
 New Application of Nuclear Imaging in the Legs May Enable Early Detection of Cardiovascular Problems 150 150 Katie Brind'Amour, PhD, MS, CHES
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Researchers have used a non-invasive imaging modality to quantify perfusion reserve in specific muscles of the extremities — a novel approach with numerous potential clinical applications Researchers have shown for the first time that SPECT/CT imaging can be used to quantify perfusion reserve of specific muscle groups in the lower limbs, which they directly related…

Keeping Options Open in Complex Pediatric Nephrolithiasis
 Keeping Options Open in Complex Pediatric Nephrolithiasis 1024 575 Lauren Dembeck
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Urologists in the Pediatric Urology Midwest Alliance recently looked at how endoscopic assisted robotic pyelolithotomy could reduce the number of procedures for children with ureteropelvic junction obstruction. The Pediatric Urology Midwest Alliance (PUMA) recently published a new report demonstrating that endoscopic assisted robotic pyelolithotomy (EARP) is an acceptable treatment option for complex cases of pediatric…

Brain Characteristics Associated with Epilepsy and Internalizing Disorders
 Brain Characteristics Associated with Epilepsy and Internalizing Disorders 1024 575 Mary Bates, PhD
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Diffuse alterations in brain structure and function are seen in youth with epilepsy and symptoms of anxiety or depression. Internalizing disorders, such as depression and anxiety, are common in patients with epilepsy. Specific brain characteristics – structural changes in the hippocampus and amygdala as well as some differences in structure and function of more frontal…

Understanding Drug Interactions in Diffuse Midline Gliomas
 Understanding Drug Interactions in Diffuse Midline Gliomas 1024 683 Lauren Dembeck
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In a recent publication in Science Translational Medicine, researchers studied combinations of approved and investigational drugs to identify promising pairs, such as panobinostat and marizomib, for the treatment of diffuse intrinsic pontine glioma (DIPG) and other diffuse midline gliomas (DMG). In recent years, studies have shown that diffuse intrinsic pontine glioma (DIPG) subtypes are driven…

Timing Steroids to Maximize Lung Benefit and Avoid Brain Harm in Premature Infants
 Timing Steroids to Maximize Lung Benefit and Avoid Brain Harm in Premature Infants 1024 575 Mary Bates, PhD
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Nurse caring for infant in Neonatal Intensive Care Unit (NICU)

Treating infants early may decrease risk of lung disease with no added risk of neurodevelopmental impairment. Steroids are used to treat extremely premature babies with respiratory failure, yet they can be associated with delays in brain development. A recent study looked at the age of first steroid administration and the risks of lung disease and neurodevelopmental impairment…

How to Increase Continuous Glucose Monitoring Utilization in Patients With Type 1 Diabetes
 How to Increase Continuous Glucose Monitoring Utilization in Patients With Type 1 Diabetes 1024 683 Katie Brind'Amour, PhD, MS, CHES
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An innovative quality improvement project grew the use of CGM nearly six-fold in 2 years. A 2017 round-table meeting of the Type 1 Diabetes Exchange revealed that some diabetes clinics had a very small number of patients using continuous glucose monitors (CGM) — devices that allow patients to avoid repeated finger sticks to check glucose…

Botox Appears Safe for Treatment of Defecation Disorders
 Botox Appears Safe for Treatment of Defecation Disorders 150 150 Kevin Mayhood
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Anal botulinum toxin injections (Botox) have increasingly been used in children with functional anorectal and colonic disorders during the past 15 years. A study at Nationwide Children’s Hospital, combined with a review of published literature, shows this off-label use of Botox is safe and complications are rare. Complications occurred in less than 0.7% of 1332…

Dentists Heeded FDA Warning on Codeine
 Dentists Heeded FDA Warning on Codeine 1024 683 Mary Bates, PhD
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open bottle of pills

An FDA black box warning directed at ENT doctors performing tonsil and adenoid surgeries also affected prescribing patterns by dentists. Codeine, an opioid analgesic, was popular in pediatrics because it was thought to be a safe alternative to morphine. However, in recent years, the drug has been found to have variability in therapeutic doses, with…

What is the Association Between Kidney Injury and Fluid Balance in Premature Newborns?
 What is the Association Between Kidney Injury and Fluid Balance in Premature Newborns? 1024 575 Mary Bates, PhD
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Nurse caring for infant in Neonatal Intensive Care Unit (NICU)

A positive fluid balance is associated with acute kidney injury and worse outcomes in a new study of premature infants. According to new research, there is an association between fluid balance and outcomes in preterm newborns, with a negative fluid balance during the first week of life emerging as a potential therapeutic target. Premature infants…

Kidney Biopsy Analysis Reveals High Risk for Disease in Patients With Sickle Cell Disease
 Kidney Biopsy Analysis Reveals High Risk for Disease in Patients With Sickle Cell Disease 1024 732 Mary Bates, PhD
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Patients with SCD are at high risk for significant kidney disease. A retrospective study of biopsy findings from the Pediatric Nephrology Research Consortium shows just how high. Kidney damage is a progressive complication of sickle cell disease (SCD), sometimes eventually leading to kidney failure. As the life expectancy of individuals with SCD has improved, the…

Lung Transplant Index Enhances Identification of Preventable Harms in Adolescents and Young Adults
 Lung Transplant Index Enhances Identification of Preventable Harms in Adolescents and Young Adults 150 150 Lauren Dembeck
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A recent Quality Improvement (QI) Initiative at Nationwide Children’s Hospital has reduced the percent of missed opportunities to address preventable harms in a population of adolescent and young adult patients who underwent lung transplant at the hospital. The study is published in Pediatric Quality and Safety. “We tried to focus on all issues, all body systems,…

Regional Anesthesia Dramatically Reduces Opioid Use After Limb Lengthening and Reconstructive Surgeries
 Regional Anesthesia Dramatically Reduces Opioid Use After Limb Lengthening and Reconstructive Surgeries 1024 584 Katie Brind'Amour, PhD, MS, CHES
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The peripheral catheter approach to postoperative pain management may also shorten length of stay. When clinicians in the Department of Anesthesiology and Pain Medicine at Nationwide Children’s Hospital first proposed the use of regional anesthesia for the patients of Christopher Iobst, MD, he was resistant to the idea. As an orthopedic surgeon specializing in limb lengthening and…

Could Restoring CD4+ T Cell Immunity Help Control Hepatitis C Infection?
 Could Restoring CD4+ T Cell Immunity Help Control Hepatitis C Infection? 1024 683 Kevin Mayhood
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Following childbirth, some women with chronic infection experienced a recovery of HCV-specific CD4+ T cells and a reduction in viral replication. In chronic hepatitis C (HCV) infections, CD4+ T cells that recognize the virus have been so hard to detect, some researchers thought they may be completely depleted. But research led by investigators at Nationwide Children’s…

Asymptomatic Infants With Congenital Cytomegalovirus May Still Have Detectable, Significant Abnormalities
 Asymptomatic Infants With Congenital Cytomegalovirus May Still Have Detectable, Significant Abnormalities 1024 575 Katie Brind'Amour, PhD, MS, CHES
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Color photo of Black father holding infant on shoulder in front of nursery background with clouds on the wall

More than half of high-risk CMV-positive newborns may have abnormalities not detected by a physical exam alone. A study in 34 infants with a normal physical exam despite a positive diagnosis of congenital cytomegalovirus (CMV) — a viral infection that can lead to neurodevelopmental delays and permanent hearing loss — found that in more than…

Targeting Alternative RNA Splicing in Pediatric Cancers
 Targeting Alternative RNA Splicing in Pediatric Cancers 150 150 Mary Bates, PhD
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Targeting alternative RNA splicing in tumor cells could lead to cancer therapies. RNA splicing, the enzymatic process of removing segments of premature RNA to produce mature RNA, is a key regulator of gene expression. Recent studies have identified variations in the transcriptomes of tumors due to alternative splicing changes, in addition to mutations in splicing…

Reducing Asthma-Related Emergency Department Visits
 Reducing Asthma-Related Emergency Department Visits 480 320 Abbie Miller
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Through serial interventions and teamwork, the initiative reduced asthma-related ED utilization rates by nearly 4% per year at a time when national rates were rising. Numerous studies have demonstrated that quality improvement (QI) methodologies improve asthma outcomes. However, moving that success from individual patients to a large population is challenging. In a recent study published…

For Some Fetuses With HLHS, One Follow-up Echocardiogram May Be Enough
 For Some Fetuses With HLHS, One Follow-up Echocardiogram May Be Enough 1024 575 Kevin Mayhood
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“Not every patient with hypoplastic left heart syndrome, also known as HLHS, is the same: there appears to be a high-risk group that has significant atrioventricular valve regurgitation, atrial septal restriction or other concerns; and a low-risk group that, on their first scan, has none of these comorbidities of the heart,” says Bernadette Richards, FASE,…

What Are Long-Term Outcomes for a Child With Bladder Exstrophy?
 What Are Long-Term Outcomes for a Child With Bladder Exstrophy? 1024 575 Kevin Mayhood
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A study from the Pediatric Urology Midwest Alliance (PUMA) suggests the condition requires lifelong management for most children with bladder exstrophy. Half of infants with classic bladder exstrophy (BE) undergo bladder augmentation or diversion by age 10 and the percentage increases with age, a 36-year retrospective study from five Midwestern children’s hospitals shows. Whether they…

Link Found Between Respiratory Syncytial Virus Infection and Asthma
 Link Found Between Respiratory Syncytial Virus Infection and Asthma 800 533 Mary Bates, PhD
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RSV infection early in life increases risk of subsequent wheezing or asthma. Respiratory syncytial virus (RSV) is the leading cause of hospitalization in infants all over the world. It can lead to serious acute infections, and new research from Nationwide Children’s shows RSV infection can also have long-term health consequences. In a new study, researchers…

Nephritis Identified as High Research Priority Area For Childhood-Onset Lupus
 Nephritis Identified as High Research Priority Area For Childhood-Onset Lupus 150 150 Lauren Dembeck
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In an effort to establish research priorities in childhood-onset systemic erythematous lupus (cSLE), researchers at Nationwide Children’s Hospital partnered with the Lupus Foundation of America (LFA) and Childhood Arthritis and Rheumatology Research Alliance (CARRA). Their findings are recently published in Pediatric Rheumatology. According to the results of their multidisciplinary prioritization survey of leading rheumatology, dermatology and…

Percutaneous Occlusion Linked to Respiratory Improvements in Low-Weight Infants with PDA
 Percutaneous Occlusion Linked to Respiratory Improvements in Low-Weight Infants with PDA 1024 575 Abbie Miller
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Nurse caring for infant in Neonatal Intensive Care Unit (NICU)

Percutaneous occlusion for patent ductus arteriosus (PDA) in infants weighing less than 6 kg is associated with potential longer term improvements in respiratory health, research by investigators at Nationwide Children’s Hospital shows. “A new device for PDA closure recently approved by the FDA has potential to reduce the incidence of device-related complications. This important work…

Targeting Cardiac-Related Strokes in Infants
 Targeting Cardiac-Related Strokes in Infants 150 150 Mary Bates, PhD
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New study describes risk factors for stroke in children with cardiac disease. Advances in surgical techniques and intensive care management have led to an increase in the number of infants surviving with cardiac disease. Unfortunately, children with cardiac disease are at higher risk for experiencing an arterial ischemic stroke. Now, a new study points to…

Does Newborn Screening Lead to Life-Span Benefits?
 Does Newborn Screening Lead to Life-Span Benefits? 1024 678 Kevin Mayhood
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To find the answer, researchers suggest data systems to track long-term care and outcomes are needed. Newborns in the United States are screened for a list of diseases, a practice that saves or improves 13,000 lives annually, the Centers for Disease Control and Prevention estimates. But, a group of health experts who helped build the…

A Deep-Learning Computer Model for Predicting Pediatric Patient Health Care Risks and Costs
 A Deep-Learning Computer Model for Predicting Pediatric Patient Health Care Risks and Costs 150 150 Kevin Mayhood
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The model, which requires fewer resources and less time to develop, outperformed traditional risk-prediction models in prospective hospitalization prediction. A deep-learning computer model was better at predicting the health care risk of 112,000 children in a Medicaid accountable care organization (ACO) than traditional risk prediction models, researchers at Nationwide Children’s Hospital have shown. “Using this…

Study Shows Three-Day Intensive Crisis Intervention is Associated with Reduced Suicidality in Adolescents
 Study Shows Three-Day Intensive Crisis Intervention is Associated with Reduced Suicidality in Adolescents 150 150 Jeb Phillips
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When an adolescent is acutely suicidal and cannot safely remain in the community, inpatient psychiatric hospitalization is the traditional intervention. But a lack of appropriate facilities across the United States, combined with an increasing demand for inpatient psychiatric services, means many young people who are at critical risk often cannot get the help they need.…

When Should Preoperative Neuromonitoring for Adolescent Idiopathic Scoliosis Be Used?
 When Should Preoperative Neuromonitoring for Adolescent Idiopathic Scoliosis Be Used? 150 150 Abbie Miller
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Study leads researchers to recommend against routine use of preoperative SSEP/TMS testing in cases of AIS requiring corrective surgery. Adolescent idiopathic scoliosis (AIS) is a coronal curvature of the spine that affects 1 to 3% of adolescents. Of these, a very small percentage – at most 0.5% – progress to the point of needing surgical…

When is Palliative Care Right for Families of Children With Single Ventricle Congenital Heart Defects?
 When is Palliative Care Right for Families of Children With Single Ventricle Congenital Heart Defects? 150 150 Kevin Mayhood
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Practitioners suggest involving a palliative care team early after diagnosis Single ventricle congenital heart defects (SV) disrupt critical blood flow and require a series of complex operations in order for a child to survive. As few as 80% of children born with SV live to age 1, 70% to age 20. Because of the high…

Rethinking Gastroesophageal Reflux Disease (GERD) in Infants
 Rethinking Gastroesophageal Reflux Disease (GERD) in Infants 150 150 Lauren Dembeck
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Novel use of existing technology points to other causes of GERD-like symptoms. While typically attributed to gastroesophageal reflux disease (GERD), supra-esophageal symptoms, such as cough, back arching and gagging, can be temporally associated with aerophagia, according to a new study by researchers at Nationwide Children’s Hospital. The findings come from the novel implementation of standard…

Improving Medication Dosing Consistency for Infants With Neonatal Abstinence Syndrome
 Improving Medication Dosing Consistency for Infants With Neonatal Abstinence Syndrome 150 150 Abbie Miller
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A quality improvement initiative effectively increases the percentage of infants dosed according to birth weight. From 2000 to 2009, prenatal maternal opiate use increased from 1.2 to 5.6 per 1,000 births, with up to 80% of in utero exposed infants requiring pharmacotherapy for neonatal abstinence syndrome (NAS). In Ohio, home of Nationwide Children’s Hospital, the exposure rate…

Calls to U.S. Poison Control Centers for Natural Psychoactive Substances Increasing, Driven by Rising Marijuana Exposures
 Calls to U.S. Poison Control Centers for Natural Psychoactive Substances Increasing, Driven by Rising Marijuana Exposures 150 150 Laura Dattner
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Researchers encourage states legalizing marijuana to implement poison prevention strategies Natural substances with psychoactive effects have been used by people for religious, medicinal and recreational purposes for millennia. Lack of regulation has led to an increase in their availability, especially online. Some psychoactive substances may be appealing to recreational users because of the perception they…

Increased Number of Pediatric Eye Injuries From Nonpowder Firearms
 Increased Number of Pediatric Eye Injuries From Nonpowder Firearms 150 150 Laura Dattner
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BB guns accounted for most of the injuries; Researchers highlight importance of protective eyewear, and call for stricter, more consistent safety legislation. Nonpowder firearms have long been marketed to children and teenagers as toys or “starter” firearms and include BB, pellet, airsoft and paintball guns. A new study conducted by researchers at the Center for Injury…

A Major Milestone in Cystic Fibrosis Treatment
 A Major Milestone in Cystic Fibrosis Treatment 1024 575 Mary Bates, PhD
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Illustration of lungs on blue silhouette of upper chest on black background

A triple medication combination could be life-changing for the majority of patients with cystic fibrosis. A Phase III clinical trial shows that elexacaftor added to ivacaftor and tezacaftor improves lung function and quality of life in cystic fibrosis patients with the most common genetic mutation, F508del. The triple therapy, known as Trikafta, could effectively treat 90%…

Predicting Acute Health Care Utilization in Patients with Pediatric Type 1 Diabetes
 Predicting Acute Health Care Utilization in Patients with Pediatric Type 1 Diabetes 150 150 Jan Arthur
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Study demonstrates the utility of a high risk assessment screening tool in differentiating between patients with versus patients without any acute health care utilization. The multidisciplinary Quality Improvement Team in the Section of Endocrinology at Nationwide Children’s Hospital, led by Manmohan Kamboj MD, FAAP, Division chief and section chief of Endocrinology, developed a brief risk screening…

Study Identifies Barriers High Schools Face When Implementing and Enforcing State Concussion Laws
 Study Identifies Barriers High Schools Face When Implementing and Enforcing State Concussion Laws 150 150 Laura Dattner
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All 50 U.S. states enacted concussion laws between 2009-2014 to mitigate the consequences of concussion. While details of the laws vary from state to state, all state laws address three main factors: concussion education; removal from play after suspected concussion; and return-to-play requirements. A new study conducted by researchers at the Center for Injury Research and…

Redirecting the Natural Immune Response to Disrupt Bacterial Biofilms
 Redirecting the Natural Immune Response to Disrupt Bacterial Biofilms 150 150 Lauren Dembeck
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A new vaccine candidate has the potential to improve outcomes for patients with chronic, recurrent diseases, such as ear infections. Could this platform technology be an important key in solving the antibiotic resistance threat? Most bacterial species prefer to live in biofilms, where they are protected from antibiotic treatments and can lead to chronic and recurrent…

Health Care Leaders Offer Interim Guidelines on Vaping and EVALI Care
 Health Care Leaders Offer Interim Guidelines on Vaping and EVALI Care 150 150 Mary Bates, PhD
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While investigations are ongoing, an interim report offers clinical guidance regarding vaping-associated lung injuries. Centers for Disease Control (CDC), the Food and Drug Administration (FDA), state and local health departments, and public health and clinical partners are looking into a multistate outbreak of lung injury associated with the use of electronic cigarette (e-cigarette), or vaping,…

Regular Physical Activities Tied to Improved Quality of Life in Adults With Fontan Circulation
 Regular Physical Activities Tied to Improved Quality of Life in Adults With Fontan Circulation 150 150 Kevin Mayhood
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Starting regular exercise in childhood can help lay the groundwork for greater health and quality of life, pediatric cardiologists suggest. Children and adults with Fontan circulation are at risk of a sedentary lifestyle. This is due in part to physicians who advise patients restrict exercise out of concern vigorous physical activity may contribute to venous…

Type of Anorectal Malformation at Birth is Predictive of Fecal Continence
 Type of Anorectal Malformation at Birth is Predictive of Fecal Continence 150 150 Kevin Mayhood
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Study also finds fecal continence rates for children born with ARMs are lower than previously reported. Recently published research shows the rate of fecal continence among 4-year-olds who underwent surgery for an anorectal malformation (ARM) as infants averages 40%, and the type of malformation — which reflects severity — is predictive of the outcome. Though…

It’s Not All About Weight: Treating and Managing Obesity in Pediatric Patients
 It’s Not All About Weight: Treating and Managing Obesity in Pediatric Patients 150 150 Abbie Miller
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Study highlights different metrics for measuring success of a weight management program for pediatrics. For pediatric patients who have severe obesity that is not well managed with the routine standard of care – diet, exercise and a meeting with a dietician – a more structured, multidisciplinary approach may be warranted. And for patients with endocrine…

Predicting Urinary Continence For a Child With Anorectal Malformation
 Predicting Urinary Continence For a Child With Anorectal Malformation 150 150 Kevin Mayhood
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Researchers suggest objective, measurable factors can be used to provide families with reasonable expectations In a child born with an anorectal malformation (ARM), anatomical features including a low-complexity ARM, high sacral ratio and a normal spine each independently predicts the child has a higher chance of urinary continence, research at Nationwide Children’s Hospital shows. “When…

Newspapers Overlook Best Practices When Reporting a Celebrity Suicide Death
 Newspapers Overlook Best Practices When Reporting a Celebrity Suicide Death 150 150 Katelyn Hanzel
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A new study shows that most articles do not adhere to suicide reporting guidelines, but experts say parents can help by starting conversations about mental health. Research shows media coverage of a celebrity suicide has the potential to increase the risk for contagion, especially among vulnerable individuals. To reduce possible harmful effects, suicide reporting guidelines…

Multicenter Data Reveals Distal Hypospadias Repair Overall Success Rate
 Multicenter Data Reveals Distal Hypospadias Repair Overall Success Rate 150 150 Katie Brind'Amour, PhD, MS, CHES
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Despite its use as an indicator of a department’s surgical skill, the reoperation rate for distal hypospadias repair has long been based on publications covering data from single-center studies — until now. Among its indicators for urologic surgery quality, U.S. News & World Report examines the complication rate for children undergoing distal hypospadias repair (relocation of the…