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Prune Belly Syndrome

Creation of Patient-Derived Induced Pluripotent Stem Cell Lines for Studying Rare Pediatric Genitourinary Disorders
 Creation of Patient-Derived Induced Pluripotent Stem Cell Lines for Studying Rare Pediatric Genitourinary Disorders 1024 683 Lauren Dembeck
By: Lauren Dembeck

Nationwide Children’s researchers create first-ever stem cell lines for rare genitourinary conditions. Induced pluripotent stem cells (iPSCs) have revolutionized medical research by providing powerful tools to study disease mechanisms, especially in rare genetic conditions. These versatile cells, derived directly from patients that have the condition, offer unprecedented opportunities to uncover the underlying genetic and cellular…

Unraveling the Genetic Mystery Behind a Rare Pediatric Disease
 Unraveling the Genetic Mystery Behind a Rare Pediatric Disease 980 429 Wendy Margolin
By: Wendy Margolin

Prune belly syndrome (PBS) is a rare, congenital urologic disease, affecting an estimated 1 out of 50,000 births. While most urologists will see fewer than three cases of PBS in their careers, Nationwide Children’s Hospital’s Linda Baker, MD, has treated more than 50 patients and met and counseled nearly 200 in the last 15 years.…

The First 3 Years With PBS: Bryson’s Story
 The First 3 Years With PBS: Bryson’s Story 953 269 Wendy Margolin
By: Wendy Margolin

The first time Andrea Williams met her new baby was four days after his birth. Baby Bryson was born with the rare congenital disorder, prune belly syndrome (PBS), and was rushed to the Nationwide Children’s Hospital NICU immediately after birth. His enlarged belly meant he was delivered by C-section at 37 weeks, and it wasn’t…

Featured Researcher — Linda Baker, MD
 Featured Researcher — Linda Baker, MD 150 150 Natalie Wilson
By: Natalie Wilson

Linda Baker, MD, a renowned expert in prune belly syndrome (PBS), joined Nationwide Children’s as a research director and principal investigator in the Kidney and Urinary Tract Center and The Ohio State University as a clinical professor of Urology at the end of 2022. Dr. Baker has met, evaluated and cared for over 180 children…

5 Things to Know About Prune Belly Syndrome
 5 Things to Know About Prune Belly Syndrome 1024 683 Abbie Miller
By: Abbie Miller
Linda Baker, MD

Linda Baker, MD, urologist, principal investigator, and one of the world’s foremost experts on prune belly syndrome, recently joined Nationwide Children’s Hospital as the co-director of the Kidney and Urinary Tract Center. She shares some important things to know about this rare disease. 1. Prune belly is a rare, congenital malformation. Prune belly syndrome (PBS)…