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Cellular Therapy

Universal Donor CAR NK Cells: A New Platform Technology for Cancer
 Universal Donor CAR NK Cells: A New Platform Technology for Cancer 1024 559 Abbie Miller
By: Abbie Miller
Intravenous (IV) chemotherapy or Cell therapy treatment bag surrounded by cancer cells, fighting the disease

A first-in-human study of universal donor CAR NK cells for acute myeloid leukemia could pave a path for a new approach to treating cancer If you ask Dean Lee, MD, PhD, the new first-in-human trial to evaluate universal donor chimeric antigen receptor (CAR) natural killer (NK) cells in patients with advanced, high-risk acute myeloid leukemia…

Growing Clinical Research at Nationwide Children’s With Cynthia Gerhardt, PhD
 Growing Clinical Research at Nationwide Children’s With Cynthia Gerhardt, PhD 1024 683 Cynthia Gerhardt, PhD and Natalie Wilson
By: Cynthia Gerhardt, PhD and Natalie Wilson

Dr. Gerhardt was appointed Chief Clinical Research Officer at Nationwide Children’s Hospital in April 2023. With integrating clinical care and research at the heart of the hospital’s strategic plan, she has big plans for ensuring our clinical research infrastructure continues to grow and evolve to support the best bench-to-bedside-and-back science for best outcomes. Learn more…

Featured Researcher — Meisam Naeimi Kararoudi, DVM, PhD
 Featured Researcher — Meisam Naeimi Kararoudi, DVM, PhD 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Meisam Naeimi Kararoudi, DVM, PhD, director of the CRISPR/Gene Editing Core and principal investigator in the Center for Childhood Cancer Research at Nationwide Children’s, has taken a winding, international road to his current role at Nationwide Children’s Hospital. From his native Iran to Italy, England, Sweden and the United States, Dr. Naeimi Kararoudi has collected…

Investigators Develop Technique to Effectively Edit NK Cells to Target Specific Cancer Cells
 Investigators Develop Technique to Effectively Edit NK Cells to Target Specific Cancer Cells 1024 649 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

The third of three major challenges in enabling the clinical potential of NK cells for cancer therapy has just been addressed, thanks to the combined talents of gene editing experts and NK cell specialists at Nationwide Children’s Hospital.   Originally, NK cells seemed promising for a natural therapy to fight cancer due to their innate…