Natural Killer Cells – Pediatrics Nationwide

Optimizing the Body’s Natural Cancer Killers

Optimizing the Body’s Natural Cancer Killers https://pediatricsnationwide.org/wp-content/uploads/2022/04/NK-Cell-Cover-Art-web-crop-1024x649.jpg 1024 649 Katie Brind'Amour, PhD, MS, CHES Katie Brind'Amour, PhD, MS, CHES https://pediatricsnationwide.org/wp-content/uploads/2021/03/Katie-B-portrait.gif April 20, 2022 April 28, 2022

By: Katie Brind'Amour, PhD, MS, CHES

April 20, 2022

Recent advances in the expansion and production of natural killer cells offers pediatric patients new hope for remission after high-risk cancer diagnoses. Natural killer (NK) cells are the innate immune system’s first line of defense for viral infections. Although these white blood cells don’t have the antigen-specific “memory” that characterizes T cells or the antibody-producing…

Administering NK Cells Post-Transplant Improves Relapse in Myeloid Malignancies

Administering NK Cells Post-Transplant Improves Relapse in Myeloid Malignancies https://pediatricsnationwide.org/wp-content/themes/corpus/images/empty/thumbnail.jpg 150 150 Mary Bates, PhD Mary Bates, PhD https://secure.gravatar.com/avatar/c6233ca2b7754ab7c4c820e14eb518c8?s=96&d=mm&r=g September 1, 2021 August 27, 2021

By: Mary Bates, PhD

September 1, 2021

A Phase I/II clinical trial demonstrates donor-derived NK cells are safe and effective at decreasing relapse and increasing survival in adults with myeloid malignancies. Haploidentical stem-cell transplantation can be a successful treatment for patients with myeloid malignancies, but relapse remains a common risk. Natural killer (NK) cells are a subset of lymphocytes capable of recognizing…