Interventional Cardiology

Investigating a Minimally Invasive Alternative to Surgery for Transverse Aortic Arch Obstruction
Investigating a Minimally Invasive Alternative to Surgery for Transverse Aortic Arch Obstruction 150 150 Erin Gregory

A new study evaluates the safety and efficacy of percutaneous balloon-expandable stents for transverse aortic arch obstruction, a form of congenital heart disease. A new study published in Circulation: Cardiovascular Interventions, conducted by Arash Salavitabar, MD, FSCAI, FPICS, FACC, FAAP, a congenital interventional cardiologist at Nationwide Children’s Hospital, and colleagues, evaluates the efficacy and safety…

Implanted Hemodynamic Monitoring in Patients With Fontan Circulation
Implanted Hemodynamic Monitoring in Patients With Fontan Circulation 150 150 Mary Bates, PhD

Pulmonary artery pressures obtained with the CardioMEMSTM system may be clinically useful. In a new study, researchers from The Ohio State University and Nationwide Children’s Hospital report on the use of invasive implanted hemodynamic monitoring (IHM) in patients with Fontan circulation. The findings suggest that IHM pressures in these patients are more closely associated with…

New Nomogram Helps Optimize 3-D Rotational Angiography for Congenital Cardiac Catheterization
New Nomogram Helps Optimize 3-D Rotational Angiography for Congenital Cardiac Catheterization 1024 775 Katie Brind'Amour, PhD, MS, CHES

Clinician-researchers studied a large number of 3-D rotational angiography (3DRA) cases to identify patient and practice factors that produce the highest quality images. In an effort to aid in the successful application of 3-D rotational angiography (3DRA) in cardiac catheterization labs worldwide, a team of clinicians at Nationwide Children’s Hospital retrospectively reviewed 208 3DRAs to…

The Heart Center Team Employs New Device to Remove High-Risk Blood Clot
The Heart Center Team Employs New Device to Remove High-Risk Blood Clot 1024 670 Emily Siebenmorgen

This first-in-pediatrics procedure was performed by Arash Salavitabar, MD, interventional cardiologist at Nationwide Children’s Hospital.  When a pediatric patient sought care for an accidental gunshot wound to the abdomen, a central line infection during his course at a large regional hospital led to a much more serious blood clot in his right atrium. His case…

First In Human
First In Human 1024 752 Abbie Miller
Top-down view of heart valves

The Heart Center at Nationwide Children’s Hospital has a long history of helping to bring innovations from the lab to the patient. The latest, the Autus Valve, aims to improve care and outcomes for children with pulmonary valve disease. In December 2021, Mark Galantowicz, MD, cardiothoracic surgeon and director of The Heart Center at Nationwide…

Stent Implantations Are an Option for Small Patients
Stent Implantations Are an Option for Small Patients 1024 670 Mary Bates, PhD

Stents that can be dilated to adult size are safe and effective for the treatment of coarctation of the aorta in young patients. Studies have demonstrated stent implantation is more effective and safer than balloon angioplasty for the treatment of coarctation of the aorta in adult and older pediatric patients. In smaller patients, however, particularly…

Transplant-Free Survival Among Children With Hypoplastic Left Heart Syndrome Undergoing Hybrid Palliation
Transplant-Free Survival Among Children With Hypoplastic Left Heart Syndrome Undergoing Hybrid Palliation 1024 683 Katie Brind'Amour, PhD, MS, CHES
Young child

The first long-term evaluation of kids with hypoplastic left heart syndrome undergoing hybrid palliation procedures finds transplant-free survival similar to that of the standard treatment at age 15 years. As one of the few teams in the world almost exclusively performing hybrid palliation surgery for babies with hypoplastic left heart syndrome (HLHS) and related congenital…

Managing Lymphatic Flow Disorders: Expanding Care Through Collaboration
Managing Lymphatic Flow Disorders: Expanding Care Through Collaboration 1024 683 Abbie Miller

Alteration in the Lymphatic System Leading to Flow Disorders The lymphatic system plays a critical role in circulating a clear to yellow-colored fluid called lymph, which contains proteins, immune factors and cells throughout the body. It is also responsible for collecting fats and fat-soluble vitamins from the gastrointestinal tract in cloudy-appearing chylous fluid. This fluid…

Technical Aspects of Fetal Aortic Valvuloplasty Predict Success of the Procedure
Technical Aspects of Fetal Aortic Valvuloplasty Predict Success of the Procedure 1024 575 Mary Bates, PhD
Fetus in utero receiving valvuloplasty

The procedure is often successful but comes with significant risks to fetal health and life. Fetal aortic valvuloplasty (FAV) is a procedure performed mid-gestation in a subset of fetuses with aortic stenosis who would likely develop hypoplastic left heart syndrome with no intervention. Although often successful, it is a high-risk procedure that is associated with…

For Some Fetuses With HLHS, One Follow-up Echocardiogram May Be Enough
For Some Fetuses With HLHS, One Follow-up Echocardiogram May Be Enough 1024 575 Kevin Mayhood

“Not every patient with hypoplastic left heart syndrome, also known as HLHS, is the same: there appears to be a high-risk group that has significant atrioventricular valve regurgitation, atrial septal restriction or other concerns; and a low-risk group that, on their first scan, has none of these comorbidities of the heart,” says Bernadette Richards, FASE,…

Percutaneous Occlusion Linked to Respiratory Improvements in Low-Weight Infants with PDA
Percutaneous Occlusion Linked to Respiratory Improvements in Low-Weight Infants with PDA 1024 575 Abbie Miller
Nurse caring for infant in Neonatal Intensive Care Unit (NICU)

Percutaneous occlusion for patent ductus arteriosus (PDA) in infants weighing less than 6 kg is associated with potential longer term improvements in respiratory health, research by investigators at Nationwide Children’s Hospital shows. “A new device for PDA closure recently approved by the FDA has potential to reduce the incidence of device-related complications. This important work…

Targeting Cardiac-Related Strokes in Infants
Targeting Cardiac-Related Strokes in Infants 150 150 Mary Bates, PhD

New study describes risk factors for stroke in children with cardiac disease. Advances in surgical techniques and intensive care management have led to an increase in the number of infants surviving with cardiac disease. Unfortunately, children with cardiac disease are at higher risk for experiencing an arterial ischemic stroke. Now, a new study points to…

Optimal Use of an FDA-Approved Device for PDA Closure in Infants
Optimal Use of an FDA-Approved Device for PDA Closure in Infants 150 150 Mary Bates, PhD

Randomized, controlled clinical trials are needed to answer questions regarding when and with whom to use the device. In January 2019, the US Food and Drug Administration approved a novel device for patent ductus arteriosus (PDA) closure in infants. The Amplatzer Piccolo Occluder is indicated for catheter-based closure of PDA in infants weighing more than…

Fetal Balloon Aortic Valvuloplasty for Critical Aortic Stenosis
Fetal Balloon Aortic Valvuloplasty for Critical Aortic Stenosis 1024 575 Abbie Miller
Fetus in utero receiving valvuloplasty

Some heart defects, such as aortic stenosis can be detected on fetal ultrasound. For some fetuses, an intervention can be beneficial before birth. Aimee Armstrong, MD, director of Cardiac Catheterization and Interventional Therapies at Nationwide Children’s Hospital, performs fetal balloon aortic valvuloplasty among other fetal heart catheterization procedures as part of the Congenital Heart Collaborative, a…

The PDA Conundrum
The PDA Conundrum 150 150 Jeb Phillips

A patent ductus arteriosus is associated with increased morbidity and mortality, but common treatments are associated with poor outcomes as well. What is a neonatologist to do? Until the mid-2000s, most neonatologists were pretty sure they knew how to handle a patent ductus arteriosus (PDA) in an infant born preterm – it needed to be…

Building Heart Valves From Extracellular Matrix
Building Heart Valves From Extracellular Matrix 150 150 Abbie Miller

Physicians at Nationwide Children’s Hospital describe the use of an extracellular matrix cylindar valve in the mitral position. At The Heart Center at Nationwide Children’s, Patrick McConnell, MD, a pediatric cardiothoracic surgeon, is using an alternative to the traditional cadaveric, mechanical or biological replacement valve. In a recent case report published in Echocardiography, Dr. McConnell and his colleagues describe the…

Family Focus Restructures Single Ventricle Care
Family Focus Restructures Single Ventricle Care 150 150 Brianne Moore

Standardize, connected care in a multidisciplinary team environment aims to improve outcomes and quality of life for patients born with single ventricle heart anatomy. Children with single ventricle anatomy, one of the most harrowing of congenital heart defects, face unique challenges that require multiple procedures and hospital admissions to treat. In most institutions, each admittance…

Taking Innovation to Heart: Next Gen Interventions in Heart Valve Disease
Taking Innovation to Heart: Next Gen Interventions in Heart Valve Disease 1024 575 Abbie Miller

From bioengineers to interventional cardiologists, molecular biologists to cardiothoracic surgeons, experts with diverse backgrounds are focusing on the problem of heart valve disease in children. Heart valve disease affects more than 5 million Americans. And while acquired disease in the adult population certainly accounts for much of this, children with heart valve disease face multiple…

First Implantable Hemodynamic Monitoring Device in Single Ventricle Fontan Anatomy
First Implantable Hemodynamic Monitoring Device in Single Ventricle Fontan Anatomy 150 150 Abbie Miller

The first IHM in a patient with Fontan anatomy and physiology enables real-time monitoring of central venous and pulmonary artery pressures. While the Fontan procedure has improved the short- and mid-term outcomes for patients born with single ventricle anatomy, long-term complications of Fontan circulation include heart failure. These complications are thought to be secondary to…