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Chronic Obstructive Pulmonary Disease

Featured Researcher: Thomas Lynch, PhD
 Featured Researcher: Thomas Lynch, PhD 150 150 Gina Vitale, PTA
By: Gina Vitale, PTA

Studying human lung development and diseases at the cellular level, such as cystic fibrosis, asthma and lung transplantation, may improve their treatment protocols. Research involving the submucosal glands, tiny disease defenders in the airways, could be the key to unlocking disease prevention or cures. Thomas Lynch, PhD, is a principal investigator in the Center for…

From Bronchopulmonary Dysplasia to Chronic Obstructive Pulmonary Disease: A Developmental Continuum
 From Bronchopulmonary Dysplasia to Chronic Obstructive Pulmonary Disease: A Developmental Continuum 1024 774 Yan Hu, PhD
By: Yan Hu, PhD
Blue-toned illustration showing lungs beside silhouettes of people across the lifespan, from a crawling baby and toddler to a child, adult, and older adult with a cane.

A Prolonged Window of Vulnerability Lung development is a highly orchestrated process that begins early in gestation and continues well into postnatal life. Following airway branching during the embryonic and pseudoglandular stages, distal lung maturation, including small airway and alveolar formation, extends through infancy and early childhood. This prolonged developmental window renders the lung particularly…