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Cardiovascular Research

Unique Cellular Trajectories Result in Reduced Cardiomyocyte Proliferation Capacities in Single Ventricle Disease
 Unique Cellular Trajectories Result in Reduced Cardiomyocyte Proliferation Capacities in Single Ventricle Disease 1024 537 Jessica Nye, PhD
By: Jessica Nye, PhD

Cellular trajectories deviate early in hypoplastic left heart syndrome (HLHS) and hypoplastic right heart syndrome (HRHS) development. Hypoplastic left and right heart syndromes are two rare and distinct single ventricle heart defects which are the most severe subtypes of congenital heart disease, usually requiring prompt surgical intervention after birth. “Clinically, there are large differences between…

Single Ventricle, Many Research Angles
 Single Ventricle, Many Research Angles 1024 658 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

An overview of the people and projects behind one of the world’s most robust single-ventricle heart disease research hubs.  In the field of single-ventricle heart disease (SVHD), there are more questions than answers. What causes the heart to form with only one ventricle? At what point in fetal development might we intervene to improve its…

Nationwide Children’s Researchers Awarded Funding to Carry Out Groundbreaking Research on Single Ventricle Heart Disease
 Nationwide Children’s Researchers Awarded Funding to Carry Out Groundbreaking Research on Single Ventricle Heart Disease 150 150 Madison Storm
By: Madison Storm

The American Heart Association (AHA) and Additional Ventures have announced funding for five teams of scientists for research on single ventricle heart disease. Four researchers from Nationwide Children’s Hospital were included in the grant awards, building off their ongoing work in regenerative medicine and cardiovascular research. These Collaborative Sciences Awards bring together researchers from various…