Bone Marrow Transplant

A New Therapeutic Era for Sickle Cell Disease
A New Therapeutic Era for Sickle Cell Disease 1024 320 Katie Brind'Amour, PhD, MS, CHES
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Transformative therapies, coupled with novel approaches to supportive care, provide increasing hope for a normal life. For more than 100 years, progress in sickle cell disease (SCD) treatment has been slow. Its mainstay treatment, hydroxyurea, approved about 30 years ago, is a repurposed cancer drug. Its first curative therapy, allogeneic hematopoietic stem cell transplant (HSCT),…

Therapy Fit for a King
Therapy Fit for a King 1024 588 Katie Brind'Amour, PhD, MS, CHES
King Robinson - a young patient at Nationwide Children's - smiling and standing next to a window inside the hospital

Marsha Marshall decided to raise King Robinson when he was just a baby at the request of his mother, Tameka Robinson, who was suffering from complications of sickle cell disease. It wasn’t long before King was diagnosed as well. For a woman in her late 50s, it was a lot to manage, especially after her…

Risk for Serious Complications From Vaccine-Preventable Infections After Hematopoietic Cell Transplant
Risk for Serious Complications From Vaccine-Preventable Infections After Hematopoietic Cell Transplant 1024 683 Katie Brind'Amour, PhD, MS, CHES

Clinician-scientists reveal the burden of vaccine-preventable infections among children post-transplant, when immunity is low and risk is high. When a hematopoietic cell transplant (HCT) recipient at Nationwide Children’s Hospital was diagnosed with a vaccine-preventable infection (VPI), treating clinicians decided to evaluate the burden of VPI in HCT patients at Nationwide Children’s and elsewhere. The team…