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Kevin Mayhood

In Extremely Preterm Babies, SNAP-II Score Predicts Brain Impairments at Age 10
 In Extremely Preterm Babies, SNAP-II Score Predicts Brain Impairments at Age 10 150 150 Kevin Mayhood
By: Kevin Mayhood

Measures taken in first 12 hours of life are associated with a host of deficits. Children born extremely preterm are known to be at increased risk of neurodevelopmental impairments, but not all babies born the same early date and weight are equal. Researchers have found that for children born at less than 28 weeks, a…

Intervention for Medically Complex Children Improves Health, Saves Money
 Intervention for Medically Complex Children Improves Health, Saves Money 800 533 Kevin Mayhood
By: Kevin Mayhood

The population-based program features coordinated care, education and feeding tube management. A population-based intervention for children with medical complexity in central and southeast Ohio led to fewer admissions, shorter hospital stays and a reduction of inpatient charges of nearly $11.8 million over 30 months, all while making children healthier. Nationwide Children’s Hospital and its affiliated…

How a QI Intervention Lowered Breast Milk Errors in a Busy NICU
 How a QI Intervention Lowered Breast Milk Errors in a Busy NICU 150 150 Kevin Mayhood
By: Kevin Mayhood

Bedside barcode scanners and dedicated milk preparation technicians helped drive the decline. A quality improvement (QI) initiative in the Neonatal Intensive Care Unit (NICU) at Nationwide Children’s Hospital has been associated with a substantial reduction in errors administering mother’s milk to these vulnerable infants. The total number of scanned errors declined from 97.1 per 1,000…

ANH Preserves Platelet Count and Function Regardless of Storage Method and Time
 ANH Preserves Platelet Count and Function Regardless of Storage Method and Time 150 150 Kevin Mayhood
By: Kevin Mayhood

Length of storage during cardiac surgeries appears to have no detrimental effects on blood. Across the United States, transfusions are standard in cardiac operating rooms, but at Nationwide Children’s Hospital, a practice geared toward limiting blood transfusion has been established and finely honed. According to a recent study from The Heart Center at Nationwide Children’s, more than…

Hospitals Should Use Genotyping to Monitor Bacterial Infections
 Hospitals Should Use Genotyping to Monitor Bacterial Infections 150 150 Kevin Mayhood
By: Kevin Mayhood

A team led by a pulmonologist-researcher found that in a children’s hospital, an unexpected pathogen emerges as a common cause of infection. The bacteria Acinetobacter baumannii is a widely-reported cause of healthcare-associated infections, particularly in adult intensive care units in developing countries. But a retrospective study of isolated cases at Nationwide Children’s Hospital found that Acinetobacter pittii recently emerged…

Two Genes Linked to Postpartum Immunity Revival in Women With Persistent Hepatitis C
 Two Genes Linked to Postpartum Immunity Revival in Women With Persistent Hepatitis C 150 150 Kevin Mayhood
By: Kevin Mayhood

Research may provide a model for identifying immune factors needed to control chronic infections. Alternative forms of two genes are associated with a boost in immunity to hepatitis C after childbirth, a study led by a Nationwide Children’s Hospital physician-researcher shows. At three months postpartum, the number of viruses circulating in the blood declined sharply…

Pediatricians and Subspecialists May Need to Up Their ADHD Game
 Pediatricians and Subspecialists May Need to Up Their ADHD Game 150 150 Kevin Mayhood
By: Kevin Mayhood

From sixth to eighth grade, Stacy Gibson sought out kids he knew had attention-deficit/hyperactivity disorder and bought their Ritalin or Adderall, sometimes by the handful. “I would party all night,then I’d take the pills to get through class. It gave me a rush of energy that I needed,” says Gibson, now 32 and in his…

A New Use for Kangaroo Care
 A New Use for Kangaroo Care 150 150 Kevin Mayhood
By: Kevin Mayhood

A parent’s touch reduces agitation, allows infants and toddlers to remain extubated after heart surgery. A small percentage of babies and young children who have undergone congenital cardiac surgery and early tracheal extubation are treated with a calming parent’s touch at Nationwide Children’s Hospital – a strategy that physicians have found works better in some…

One Dose Probiotic Biofilm Protects Against NEC
 One Dose Probiotic Biofilm Protects Against NEC 150 150 Kevin Mayhood
By: Kevin Mayhood

Probiotic biofilm enables the beneficial bacteria to withstand stomach acid, promote microbial activity and decrease intestinal inflammation. A single dose of a probiotic biofilm grown on microspheres prevented or significantly reduced the severity of necrotizing enterocolitis (NEC) in animal models of the disease, researchers show. This delivery method not only appears to protect against NEC…

Novel Practice Pathway Addresses Problem Behaviors Among Patients With Autism
 Novel Practice Pathway Addresses Problem Behaviors Among Patients With Autism 150 150 Kevin Mayhood
By: Kevin Mayhood

Pediatricians urged to investigate underlying causes. Issues causing children with autism spectrum disorder to be irritable or belligerent can be difficult for parents, teachers and other care providers to uncover. And, wait times to see a specialist may leave a child frustrated, distressed or in physical pain for months. Primary care physicians who see the…

Minimally-Invasive Technology Proving Itself in Epilepsy Procedures
 Minimally-Invasive Technology Proving Itself in Epilepsy Procedures 150 150 Kevin Mayhood
By: Kevin Mayhood

MRI-guided stereotactic laser ablation may become the option of choice for appropriate patients. MRI-guided stereotactic laser ablation is proving comparable to open surgery in several procedures aimed at controlling epilepsy, researchers report. Importantly, patients’ recovery is considerably easier and shorter than recuperation from traditional surgeries, and while thorough studies are needed, early results indicate fewer…

Use Caution When Prescribing a Gluten-Free Diet
 Use Caution When Prescribing a Gluten-Free Diet 150 150 Kevin Mayhood
By: Kevin Mayhood

A gluten-free diet makes diagnosing underlying conditions difficult and can leave potential, long-term consequences unaddressed. The growing popularity of a gluten-free diet among adults appears to be spilling over to children, with help from the pediatrician’s office. “An increasing number of primary care physicians, who are seeing children with symptoms possibly related to gluten intolerance,…

Neurologists Urged to Consider MCA When Evaluations Don’t Support Claims
 Neurologists Urged to Consider MCA When Evaluations Don’t Support Claims 150 150 Kevin Mayhood
By: Kevin Mayhood

Up to half of medical child abuse cases include neurological symptoms Medical child abuse (MCA) is highly variable, but neurologists are in a position to help detect up to half of these cases, researchers at Nationwide Children’s Hospital report. Consistent with the authors’ clinical experience, studies estimate that abusive caregivers make up, exaggerate or induce…

Signaling Pathway Changes May Flag CAVD, Offer Target for Therapies
 Signaling Pathway Changes May Flag CAVD, Offer Target for Therapies 150 150 Kevin Mayhood
By: Kevin Mayhood

Loss of TgfB1 from the endothelium leads to a reduction in Sox9 expression and valve calcification. A team of researchers has identified a molecular signaling pathway that, when altered, can contribute to calcific aortic valve disease (CAVD). The finding may provide a method for early diagnosis — many patients don’t learn they have the disease until it’s in the final…

Predicting Risk for Chronic Renal Disease in Children
 Predicting Risk for Chronic Renal Disease in Children 150 150 Kevin Mayhood
By: Kevin Mayhood

Studies using a new contrast agent have the potential to determine if infants born premature develop a full complement of nephrons. A new magnetic resonance imaging contrast agent enables researchers to see the number and volume of blood-filtering nephrons in rodent kidneys and donated human adult kidneys, potentially offering a way to diagnose chronic renal disease far earlier than current…

Identifying Characteristics Associated With Timely Follow-Up Psychiatric Care
 Identifying Characteristics Associated With Timely Follow-Up Psychiatric Care 150 150 Kevin Mayhood
By: Kevin Mayhood

Nearly one in three youths with mood disorders receive no outpatient care within 30 days of psychiatric hospital discharge. More than diagnoses and demographics influence whether youths receive critical outpatient care following psychiatric hospitalization. Individual attributes and aspects of the hospital where they receive treatment as well as the community they live in play roles, researchers from The Ohio State…

Weaning Babies with NAS Better and Faster
 Weaning Babies with NAS Better and Faster 150 150 Kevin Mayhood
By: Kevin Mayhood

Protocol enables babies born addicted to opioids to be weaned off the drugs faster. Adoption of a strict protocol has enabled six regional perinatal centers across Ohio to wean babies exposed to opioids in utero off drugs faster, send them home sooner and lower the use of adjunctive drugs, new research shows. In response to the skyrocketing…

Researchers Find Signatures of Rhinovirus Infection and Incidental Presence
 Researchers Find Signatures of Rhinovirus Infection and Incidental Presence 150 150 Kevin Mayhood
By: Kevin Mayhood

Transcriptional profiling may speed discrimination between the two, aiding in clinical decisions. Transcriptional profiling, measuring the activity of thousands of genes at once to create a snapshot of cellular function, may make quick work of discriminating between active rhinovirus infection and incidental virus detection — and improve clinical decisions — researchers from Nationwide Children’s Hospital…

Omega-3 Supplements Tied to Notable, Sustained Mental Health Improvements
 Omega-3 Supplements Tied to Notable, Sustained Mental Health Improvements 150 150 Kevin Mayhood
By: Kevin Mayhood

Case study shows reduction in bipolar youth’s psychotic mania, depression and anxiety Medications unchanged, a severely bipolar girl’s depressive, manic and psychotic symptoms improved significantly during the two years her mother added omega-3 supplements to her daily diet. The case, reported by researchers at Nationwide Children’s Hospital and Ohio State University Wexner Medical Center, is…

Mouse Model Reflects Small Population but Could Provide Big Payoff
 Mouse Model Reflects Small Population but Could Provide Big Payoff 150 150 Kevin Mayhood
By: Kevin Mayhood

First model of exon duplication causing DMD enables testing for potential therapies Duplication of exons, the parts of a gene that code for amino acids, cause six to 10 percent of cases of Duchenne muscular dystrophy, which is due to mutations in theDMD gene.  New research suggests skipping, or excluding, one copy of a duplicated exon during assembly…

Common Infections Associated With Childhood Stroke
 Common Infections Associated With Childhood Stroke 150 150 Kevin Mayhood
By: Kevin Mayhood

Routine vaccinations appear to be protective. Minor infections, including the common cold, appear to trigger arterial ischemic stroke (AIS) in children, an international study shows. At the same time, a full or nearly full regimen of childhood immunizations appears to be protective in children. The research, published in the journal Neurology, also indicates long-suspected cold medicines don’t…

New Drug Advances Cystic Fibrosis Care
 New Drug Advances Cystic Fibrosis Care 150 150 Kevin Mayhood
By: Kevin Mayhood

Orkambi helps reduce infections and slows loss of lung function in some patients. Matt Hennessey knew he was on the experimental medicine and not a placebo just days after he began participating in a drug trial. He felt better. The addition of Orkambi pills to his daily routine was just another part of his maintenance…

Marijuana Exposure in Young Children
 Marijuana Exposure in Young Children 150 150 Kevin Mayhood
By: Kevin Mayhood

Researchers call for states to enact controls protecting all minors. When states legalize marijuana for medical or recreational use, the number of children younger than 6 exposed to the drug spikes that year and continues to rise annually, researchers at Nationwide Children’s Hospital report. And the number of children classified as victims of major exposures…

Suicides Rising Among Young Black Children, Rural Adolescents
 Suicides Rising Among Young Black Children, Rural Adolescents 150 150 Kevin Mayhood
By: Kevin Mayhood

Researchers are parsing data for trends and intervention targets. Researchers in central Ohio are gaining surprising insights they hope will lead to fewer children and adolescents committing suicide. While the suicide rate among white children 5 to 11 years old has declined since 1993, the rate among black children in the same age group has…

Orphan Disease Seeks Parents, Funding
 Orphan Disease Seeks Parents, Funding 1024 575 Kevin Mayhood
By: Kevin Mayhood
Color photo, family portrait of Reagan, a young girl with an orphan disease, her parents, and their dog

Research on rare pediatric diseases often remains underfunded and obscure until motivated families give scientists — and their own children — a much-needed shot at potential therapies worthy of federal funding. Reagan McGee’s pediatrician couldn’t figure out why she had cold after cold. Her parents, Karin and Peter McGee, took her to an ear, nose and…

To Rest or Not To Rest?
 To Rest or Not To Rest? 150 150 Kevin Mayhood
By: Kevin Mayhood

Ebola in Children Creates Ethical Quandary
 Ebola in Children Creates Ethical Quandary 150 150 Kevin Mayhood
By: Kevin Mayhood

Do you keep a parent in the room while the virus rages inside a child? The Ebola outbreak in Guinea, Liberia and Sierra Leone has challenged emergency preparedness at Children’s Hospitals and Clinics of Minnesota like nothing before — even more than the early days of AIDS and outbreaks of measles and H1N1 flu, says Infection Prevention…

Probing for Links Between Psychotropic Drugs and Severe Liver Disease
 Probing for Links Between Psychotropic Drugs and Severe Liver Disease 150 150 Kevin Mayhood
By: Kevin Mayhood

Drugs that help minors with severe mental health disorders may put overweight and obese patients at risk for severe liver disease. In a paper that appears to be the first to suggest the connection, the authors point out that youths who suffer from psychiatric illnesses are already at greater risk for obesity and its comorbidities.…

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