Study Explores Impact of Duffy Null Phenotype on Neutrophil Count and Hydroxyurea Dosing in Children With Sickle Cell Disease
Study Explores Impact of Duffy Null Phenotype on Neutrophil Count and Hydroxyurea Dosing in Children With Sickle Cell Disease https://pediatricsnationwide.org/wp-content/uploads/2021/03/AdobeStock_4366150-1024x683.jpg 1024 683 Lauren Dembeck https://pediatricsnationwide.org/wp-content/uploads/2021/03/Dembeck_headshot.gif
Children with sickle cell disease and the Duffy null phenotype may have lower measured neutrophil counts, but new research suggests that there are opportunities to optimize hydroxyurea regardless of Duffy null status. Sickle cell disease (SCD) primarily affects individuals of minority populations and can cause numerous morbidities, including vaso-occlusive pain, acute chest syndrome episodes, and…