Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases

Learn More

Unraveling the Genetic Mystery Behind a Rare Pediatric Disease

Read More

New National “Vital Signs” to Measure Population-wide Pediatric Health

Find Out More
Close
Enter your
text here
Cardiopulmonary Rehabilitation Post-COVID: Could Your Patient Benefit?
 Cardiopulmonary Rehabilitation Post-COVID: Could Your Patient Benefit? 1024 728 Abbie Miller
By:

The road to recovery from COVID-19, the disease caused by SARS-CoV-2, is not always smooth, short or straight. For adults and children, long COVID, a condition where symptoms such as fatigue, headache and decreased respiratory function persist after the virus has “cleared” the body,…

read more
How Do Children With IBD and Their Caregivers Perceive Biosimilars?
 How Do Children With IBD and Their Caregivers Perceive Biosimilars? 640 427 JoAnna Pendergrass, DVM
By:

Many pediatric patients with inflammatory bowel disease and their caregivers are unaware of biosimilars, creating an opportunity for providers to educate patients and their families about this effective and less expensive treatment option. Infliximab is a biologic therapy that effectively manages inflammatory bowel disease…

read more
BRUE: What Is It? How Is It Treated?
 BRUE: What Is It? How Is It Treated? 1024 575 Abbie Miller
By:

BRUE –brief resolved unexplained event – whether you pronounce it brew-EE or brOO, it might be a term you haven’t run across since medical school. In a recent resident-led episode of PediaCast CME, Meghan Fennell, MD, and Vanessa Thiel, MD, break down everything you…

read more
Featured Researcher — Ashley Jackson, PhD
 Featured Researcher — Ashley Jackson, PhD 150 150 Natalie Wilson
By:

Ashley Jackson, PhD, is a principal investigator in The Kidney and Urinary Tract Center at Nationwide Children’s studying renal urothelium, the special surface tissue that lines most of the urinary tract, or the drainage system of the kidneys, to slow kidney disease progression in…

read more
Functional Neurological Disorders: What Pediatric Neurologists Should Know
 Functional Neurological Disorders: What Pediatric Neurologists Should Know 150 150 Mary Bates, PhD
By:

The diagnosis is common, yet this group of disorders has been subjected to confusion and stigma throughout history. Functional neurological disorders are a collection of disorders in which patients experience neurological symptoms, such as numbness, weakness, seizure-like events, or abnormal gait or movements, but…

read more
Self-Harm Risk Among Youth With First-Episode Psychosis
 Self-Harm Risk Among Youth With First-Episode Psychosis 1024 575 Mary Bates, PhD
By:

Study narrows down period of acute risk and finds shared and unique risk factors among adolescents and young adults. Although it is known that young people with psychosis are at an elevated risk for suicide and suicide-related behavior, it has not been clear which…

read more
Variability in Cardiac Diagnostics and Therapies for Patients with Duchenne Muscular Dystrophy
 Variability in Cardiac Diagnostics and Therapies for Patients with Duchenne Muscular Dystrophy 1024 670 Mary Bates, PhD
By:

Survey shows different approaches to cardiac diagnostics and therapy among a multicenter collaborative network. Cardiac disease is a major cause of mortality in Duchenne muscular dystrophy (DMD), yet data regarding outcomes and cardiac disease progression are lacking. This has led to a highly variable…

read more
The True History of the Nuremberg Code: Leo Alexander’s Blueprint Uncovered
 The True History of the Nuremberg Code: Leo Alexander’s Blueprint Uncovered 150 150 Abbie Miller
By:

An investigation of Duke University’s Medical Center’s Archives boxes labeled “Alexander’s Papers” reveals a document containing six principles, which were included nearly word-for-word in the Nuremberg Code.  At the end of the famous Doctors’ Trial, the trial of Nazi doctors for their crimes and…

read more
Featured Researcher — Juhi Bagaitkar, PhD
 Featured Researcher — Juhi Bagaitkar, PhD 150 150 Katie Brind'Amour, PhD, MS, CHES
By:

Juhi Bagaitkar, PhD, a principal investigator in the Center for Microbial Pathogenesis at the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital, studies how immune cells and barrier epithelial cells (the cells that cover all internal and external surfaces in the body) protect…

read more
Novel Compound Shows Promise for Treating Nephrotic Syndrome
 Novel Compound Shows Promise for Treating Nephrotic Syndrome 1024 575 Mary Bates, PhD
By:

PPARγ selective modulator appear to be more efficacious in reducing proteinuria and comorbidities, and has fewer side effects than a traditional PPARγ agonist in a preclinical model of nephrotic syndrome. Nephrotic syndrome, characterized by high proteinuria, is one of the most common forms of…

read more
Girl sitting on a bench with her phone smiling.
Hydroxyurea Dose and Adherence Affect Hematologic Outcomes in Children With Sickle Cell Disease
 Hydroxyurea Dose and Adherence Affect Hematologic Outcomes in Children With Sickle Cell Disease 1024 683 JoAnna Pendergrass, DVM
By:

Optimal hydroxyurea dosing and medication adherence can improve hematologic outcomes for children with sickle cell anemia.   For pediatric patients with sickle cell anemia, hydroxyurea is highly effective at reducing disease complications. However, it can be challenging for these patients to take hydroxyurea for…

read more
sleeping infant
Nafcillin is a Safe Alternative to Vancomycin for Empirical Treatment of Late-Onset Sepsis Among Infants in the NICU
 Nafcillin is a Safe Alternative to Vancomycin for Empirical Treatment of Late-Onset Sepsis Among Infants in the NICU 1024 681 Mary Bates, PhD
By:

Guidelines to reduce vancomycin use at three Ohio NICUs did not impact mortality rate. In 2014, the Neonatal Antimicrobial Stewardship Program at Nationwide Children’s Hospital recommended nafcillin rather than vancomycin for empirical therapy of possible late-onset sepsis in infants without a history of methicillin-resistant…

read more
A More Efficient Method for Diagnosing Electrical Status Epilepticus in Sleep?
 A More Efficient Method for Diagnosing Electrical Status Epilepticus in Sleep? 375 280 Mary Bates, PhD
By:

Calculating the spike-wave index of the EEG of just the first 100 seconds of sleep is enough for diagnosis. Electrical status epilepticus in sleep (ESES) is an electrographic pattern in which epileptiform activity is dramatically activated by sleep. The ESES pattern is a key…

read more
When Functional Outcomes Are Achieved Post-Op, Do Patients and Families Care About Scarring?
 When Functional Outcomes Are Achieved Post-Op, Do Patients and Families Care About Scarring? 1024 683 Abbie Miller
By:

A recent editorial from Dr. Daniel DaJusta questions whether cosmetic concerns after surgery are primarily driven by surgeons, patients or parents. It is widely accepted that having a smaller, neater or less visible scar following surgery is a preferable cosmetic outcome to a large,…

read more
NASPGHAN: New Guidance for Surgical Procedure Selection in Pediatric Chronic Pancreatitis
 NASPGHAN: New Guidance for Surgical Procedure Selection in Pediatric Chronic Pancreatitis 899 450 Katie Brind'Amour, PhD, MS, CHES
By:

Informed, multispecialty decision-making is essential to give children with chronic pancreatitis the best chance for long-term pain relief and improved quality of life, according to new guidance issued by the North American Society for Pediatric Gastroenterology, Hepatology & Nutrition.   Chronic pancreatitis has long…

read more
Strategies and Resources for Managing Anxiety in Pediatric Patients
 Strategies and Resources for Managing Anxiety in Pediatric Patients 1024 575 Katie Brind'Amour, PhD, MS, CHES
By:

Anxiety disorders are one of the most common mental health diagnoses affecting children, making regular assessment and robust care resources essential to both primary and specialty care practices. Data from 2016-2019 report indicates that nearly 1 in 10 children ages 3-17 have ever been…

read more
Close up color photo of little boy holding hands on his belly
Is 3D Anorectal Manometry Preferable to Traditional Anorectal Manometry in Children With Functional Constipation?
 Is 3D Anorectal Manometry Preferable to Traditional Anorectal Manometry in Children With Functional Constipation? 1024 680 Mary Bates, PhD
By:

Study finds 3D-ARM is less comfortable and does not provide additional information compared to traditional ARM.   In a recent pilot study, researchers from Nationwide Children’s compared outcomes and patient experience of a new three-dimensional (3D) anorectal manometry (ARM) technique compared to regular ARM…

read more
Illustrations of clock faces at different times and angles
When Every Week Matters: Advancing a Treatment to the Clinic
 When Every Week Matters: Advancing a Treatment to the Clinic 1024 491 Natalie Wilson
By:

Researchers and regulatory experts bring a potential new therapy for a deadly neurodegenerative disease from IND application to clinical trial enrollment in a matter of weeks, setting a new standard in translating therapies from bench to bedside. In October 2021, the Office of Research…

read more
Optimizing the Body’s Natural Cancer Killers
 Optimizing the Body’s Natural Cancer Killers 1024 649 Katie Brind'Amour, PhD, MS, CHES
By:

Recent advances in the expansion and production of natural killer cells offers pediatric patients new hope for remission after high-risk cancer diagnoses. Natural killer (NK) cells are the innate immune system’s first line of defense for viral infections. Although these white blood cells don’t…

read more
How Does Allergic Disease Protect Against Developing Asthma After Viral Infection?
 How Does Allergic Disease Protect Against Developing Asthma After Viral Infection? 1024 523 Mary Bates, PhD
By:

Neutrophils and IL-4 are critical in preventing post-viral airway disease in mice with pre-existing allergic disease. In a new study, researchers from Nationwide Children’s Hospital show that in a mouse mode simulating human respiratory viral infection, pre-existing allergic disease prevents the development of asthma…

read more