Osteosarcoma

Featured Researcher – Ryan Roberts, MD, PhD
Featured Researcher – Ryan Roberts, MD, PhD 150 150 Gina Vitale

Ryan D. Roberts, MD, PhD, is a physician in the Division of Hematology and Oncology at Nationwide Children’s Hospital and a principal investigator for the Center for Childhood Cancer at the Abigail Wexner Research Institute at Nationwide Children’s Hospital. He is a member of the Translational Therapeutics research program at The James Comprehensive Cancer Center…

Interactions Between Invading Tumor and Lung Cells Permit Metastatic Lung Colonization of Osteosarcoma
Interactions Between Invading Tumor and Lung Cells Permit Metastatic Lung Colonization of Osteosarcoma 150 150 Lauren Dembeck

Survival signals elicited by lung tissue interactions promote osteosarcoma metastasis and represent a promising target for clinical trials in both human and canine patients.   Osteosarcoma, the most common primary tumor of bone, occurs predominantly in children, teens and young adults. Patient survival largely depends upon the presence or absence of metastasis. Within five years…