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Osteosarcoma

From Biology to Bedside: How the Center for Childhood Cancer Research Is Shaping What Comes Next
 From Biology to Bedside: How the Center for Childhood Cancer Research Is Shaping What Comes Next 1024 627 Madison Storm
By: Madison Storm
Portrait of Alexander Bishop, DPhil, standing in a hospital lobby and smiling, wearing a navy blazer and light blue shirt.

An interview with Alexander Bishop, DPhil, director of the Center for Childhood Cancer Research, principal investigator and Richard J. Solove Endowed Chair in Cancer Clinical Developmental Therapeutics at Nationwide Children’s Hospital. At Nationwide Children’s Hospital, the mission of the Center for Childhood Cancer Research (CCCR) is to expand the understanding of childhood cancer pathogenesis and…

Featured Researcher – Ryan Roberts, MD, PhD
 Featured Researcher – Ryan Roberts, MD, PhD 150 150 Gina Vitale, PTA
By: Gina Vitale, PTA

Ryan D. Roberts, MD, PhD, is a physician in the Division of Hematology and Oncology at Nationwide Children’s Hospital and a principal investigator for the Center for Childhood Cancer at the Abigail Wexner Research Institute at Nationwide Children’s Hospital. He is a member of the Translational Therapeutics research program at The James Comprehensive Cancer Center…

Interactions Between Invading Tumor and Lung Cells Permit Metastatic Lung Colonization of Osteosarcoma
 Interactions Between Invading Tumor and Lung Cells Permit Metastatic Lung Colonization of Osteosarcoma 150 150 Lauren Dembeck
By: Lauren Dembeck

Survival signals elicited by lung tissue interactions promote osteosarcoma metastasis and represent a promising target for clinical trials in both human and canine patients.   Osteosarcoma, the most common primary tumor of bone, occurs predominantly in children, teens and young adults. Patient survival largely depends upon the presence or absence of metastasis. Within five years…