hypoplastic left heart syndrome

Unique Cellular Trajectories Result in Reduced Cardiomyocyte Proliferation Capacities in Single Ventricle Disease
Unique Cellular Trajectories Result in Reduced Cardiomyocyte Proliferation Capacities in Single Ventricle Disease 1024 537 Jessica Nye, PhD

Cellular trajectories deviate early in hypoplastic left heart syndrome (HLHS) and hypoplastic right heart syndrome (HRHS) development. Hypoplastic left and right heart syndromes are two rare and distinct single ventricle heart defects which are the most severe subtypes of congenital heart disease, usually requiring prompt surgical intervention after birth. “Clinically, there are large differences between…

Advancing Care for Infants with Hypoplastic Left Heart Syndrome: New Insights into Maternal and Community Health Factors
Advancing Care for Infants with Hypoplastic Left Heart Syndrome: New Insights into Maternal and Community Health Factors 1024 537 Pam Georgiana

Nationwide Children’s Heart Center explores the impact of maternal and social determinants of health on congenital heart disease. While maternal-fetal environment factors are known to impact outcomes in babies who receive the traditional Norwood surgery to treat hypoplastic left heart syndrome (HLHS), there is little research on how the maternal-fetal environment affects outcomes after the…