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AML

Identifying Ancestry-Based Predictors of Survival in Black Patients with Acute Myeloid Leukemia
 Identifying Ancestry-Based Predictors of Survival in Black Patients with Acute Myeloid Leukemia 1024 768 Alaina Doklovic
By: Alaina Doklovic

Researchers use multiomic profiling to understand ancestry-specific aspects of cancer onset and outcomes. In a recent study, published in ­­­Nature Genetics, researchers from Nationwide Children’s Hospital and The Ohio State University Comprehensive Cancer Center (OSUCCC – James) compared genomic profiles of patients diagnosed with AML having self-reported and genomically-confirmed African ancestry and to patients diagnosed…

Donor-Derived NK Cells Safe and Efficacious in Relapsed and Refractory AML
 Donor-Derived NK Cells Safe and Efficacious in Relapsed and Refractory AML 1024 649 Lauren Dembeck
By: Lauren Dembeck
artistic rendering of an NK cell on a faded blue background with other cells faintly visible in the background

Researchers have used their approach for growing large numbers of NK cells to allow repeated dosing for a more effective and less toxic treatment.   Outcomes for patients with relapsed and refractory acute myeloid leukemia (R/R AML) have not significantly improved over the last 30 years. For example, a recent study of patients treated with…