Bladder

Refining the Role of Basal Urothelial Cells in Bladder Development
Refining the Role of Basal Urothelial Cells in Bladder Development 1024 683 Jessica Nye, PhD

Basal keratin 5 urothelial cells (K5-UCs) were found to be age-restricted progenitors in bladders and their progenitor potential could be rescued by exogenous proliferative cues.   “The identity of the bladder urothelium progenitor is controversial and confounded by slow turnover, and a low mitotic index during homeostasis,” says Ashley R. Jackson, PhD, principal investigator in…