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Pathology

Featured Researcher — Diana Thomas, MD, PhD
 Featured Researcher — Diana Thomas, MD, PhD 150 150 Katie Brind'Amour, PhD, MS, CHES
By: Katie Brind'Amour, PhD, MS, CHES

Diana Thomas, MD, PhD, joined the Biopathology Center (BPC) at Nationwide Children’s Hospital as its pathology operations director in 2021. Since then, she has been busy supporting research protocol development and the receipt, processing, banking and distribution of biospecimens for clinical and research investigators around the world. As a biorepository for some of the largest…

Molecular Toolset: Real-Time Screening for SARS-CoV-2 Variants
 Molecular Toolset: Real-Time Screening for SARS-CoV-2 Variants 1024 683 Lauren Dembeck
By: Lauren Dembeck

Tracking variants of concern or interest is critical to inform public health decisions and to ensure patients receive the best available COVID-19 treatments for SARS-CoV-2 infections. Researchers at Nationwide Children’s Hospital and The Ohio State University (OSU) have developed a set of mutation-specific tests with same-day reporting that can detect five variants of concern (VOCs)…

Improving Feeding and Growth in Children With Cleft Palate
 Improving Feeding and Growth in Children With Cleft Palate 1024 575 Mary Bates, PhD
By: Mary Bates, PhD
Black and white photo of baby bottle with formula on the table in front of a simple background

Targeted interventions result in improved feeding efficiency and growth in infants with cleft lip and/or palate. Cleft lip and/or palate is a relatively common birth defect that occurs when certain parts of the face and mouth fail to fuse during development. Infants with the condition can struggle to suck or extract liquid from the breast…

What Happens When Cancer Remission Is in Question?
 What Happens When Cancer Remission Is in Question? 1024 575 Mary Bates, PhD
By: Mary Bates, PhD
Photo of leukemia cells under microscope

A new study looks at outcomes for children with leukemia when two tests of remission disagree. In both clinical practice and clinical trials, remission in leukemia is determined by morphological assessment — a person counting cancer cells in a bone marrow sample under a microscope. But more sophisticated technologies, such as flow cytometry or polymerase…