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Cardiovascular Surgery

Don’t Oversize Your Tissue-Engineered Vascular Grafts: Insights for the Translation of New Surgical Technologies
 Don’t Oversize Your Tissue-Engineered Vascular Grafts: Insights for the Translation of New Surgical Technologies 1024 683 Abbie Miller
By: Abbie Miller

Study shows that adoption of a tissue engineered vascular graft technology currently in clinical trials would require a shift in surgical approach. Tissue engineered vascular grafts (TEVGs) are designed to overcome two important problems associated with synthetic conduits used in surgeries for children with congenital heart disease (CHD): the lack of growth potential and the…

Tissue-Engineered Vascular Grafts Resist Calcification
 Tissue-Engineered Vascular Grafts Resist Calcification 968 1024 Abbie Miller
By: Abbie Miller

Dystrophic calcification is the biggest reason for prosthetic biomaterial failure. Compared to expanded poly(tetrafluoroethylene) (PTFE) grafts, tissue-engineered vascular grafts (TEVGs) exhibited superior durability, including reduced late-term calcification, according to a study published in Nature Communications. “All of the biomaterials we routinely use for cardiovascular surgery are susceptible to dystrophic calcification,” says Christopher Breuer, MD, pediatric…