Respiratory Syncytial Virus

Featured Researcher — Katherine Bline, MD
Featured Researcher — Katherine Bline, MD 150 150 Katie Brind'Amour, PhD, MS, CHES

Katherine Bline, MD, is a critical care medicine physician and principal investigator in the Center for Vaccines and Immunity at Nationwide Children’s Hospital. Experience caring for some of the hospital’s sickest children in the pediatric intensive care unit (PICU) and mentors who pushed her to understand phenomena she observed clinically have helped Dr. Bline find…

The Impact and Implications of Interferons Against RSV
The Impact and Implications of Interferons Against RSV 1024 575 Emily Siebenmorgen
Illustration of lungs on blue silhouette of upper chest on black background

Specific cytokines play a key role in minimizing disease severity Respiratory syncytial virus (RSV) shares many symptoms with other respiratory viruses like the common cold or the flu, but it represents the number one cause of hospitalization in infants worldwide. Despite being a large burden on the health care system, there are currently few preventative…

Codetection of Respiratory Bacteria in Infants With RSV Infection Associated With Worse Outcomes
Codetection of Respiratory Bacteria in Infants With RSV Infection Associated With Worse Outcomes 1024 575 Lauren Dembeck
Color photo of Black father holding infant on shoulder in front of nursery background with clouds on the wall

The interaction between the bacteria and respiratory syncytial virus (RSV) appears to be synergistic. Researchers are now working to understand the underlying biological mechanisms. Researchers at Nationwide Children’s Hospital have discovered that codetection of Haemophilus influenzae and Streptococcus pneumoniae in the upper respiratory tract of previously healthy infants with RSV infection was independently associated with…

Link Found Between Respiratory Syncytial Virus Infection and Asthma
Link Found Between Respiratory Syncytial Virus Infection and Asthma 800 533 Mary Bates, PhD

RSV infection early in life increases risk of subsequent wheezing or asthma. Respiratory syncytial virus (RSV) is the leading cause of hospitalization in infants all over the world. It can lead to serious acute infections, and new research from Nationwide Children’s shows RSV infection can also have long-term health consequences. In a new study, researchers…

Surprise Finding in Respiratory Syncytial Virus Infection Viral Load Study
Surprise Finding in Respiratory Syncytial Virus Infection Viral Load Study 150 150 Lauren Dembeck

Understanding viral load dynamics can help inform treatment decisions Respiratory syncytial virus (RSV) lower respiratory tract infection is a leading cause of hospitalization and mortality in infants worldwide, but a licensed RSV vaccine has not yet been developed, in part due to the incomplete understanding of RSV pathogenesis. While investigating the relationship between RSV viral…

On the Road to Eliminating RSV
On the Road to Eliminating RSV 150 150 Abbie Miller

With the recent publication of two papers, researchers shed light on factors that influence disease severity and immune response to respiratory syncytial virus infection in infants and young children. “RSV is a very common infection in infants and young children – almost everyone will be infected by age 2. In the United States, 2-3 percent…