Optimizing Prenatal and Neonatal Care for Infants With Treatable Rare Diseases

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Unraveling the Genetic Mystery Behind a Rare Pediatric Disease

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New National “Vital Signs” to Measure Population-wide Pediatric Health

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To Rest or Not To Rest?
 To Rest or Not To Rest? 150 150 Kevin Mayhood
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Ebola in Children Creates Ethical Quandary
 Ebola in Children Creates Ethical Quandary 150 150 Kevin Mayhood
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Do you keep a parent in the room while the virus rages inside a child? The Ebola outbreak in Guinea, Liberia and Sierra Leone has challenged emergency preparedness at Children’s Hospitals and Clinics of Minnesota like nothing before — even more than the early days of…

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A Shift in the Antibiotic Prophylaxis Debate?
 A Shift in the Antibiotic Prophylaxis Debate? 150 150 Katie Brind'Amour, PhD, MS, CHES
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The RIVUR trial laid to rest certain questions surrounding antimicrobial prophylaxis in children with vesicoureteral reflux. But it also launched a new debate. The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) trialwas supposed to provide clear direction for pediatric urologists. To date, it…

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Conflicting Directions for BPD Treatment
 Conflicting Directions for BPD Treatment 150 150 Katie Brind'Amour, PhD, MS, CHES
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Treatment of bronchopulmonary dysplasia differs dramatically among institutions. But why does variation matter? Recent studies report extreme variation among hospitals ordering three common medications for chronic lung disease, or bronchopulmonary dysplasia, calling into question the appropriateness of their use and the reason for their…

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Placental Transfusion Confusion
 Placental Transfusion Confusion 150 150 Katie Brind'Amour, PhD, MS, CHES
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Medical professional organizations cannot reach consensus regarding delayed cord clamping and umbilical cord “milking.” Nearly every relevant professional organization has its own recommendations for placental transfusion techniques known as delayed umbilical cord clamping and milking. But it’s unclear whether additional research will lead to…

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Beyond the Basics: Enrolling Children in Research
 Beyond the Basics: Enrolling Children in Research 150 150 Katie Brind'Amour, PhD, MS, CHES
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The ethics of pediatric research include far more than the concepts of autonomy and assent. Consent and assent. Competence and autonomy. Physicians are familiar with the catchphrases of ethical research, but the deeper researchers dig, the more they find that the field’s current understanding…

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Study Finds Cow’s Milk is Added to Breast Milk and Sold to Parents Online
 Study Finds Cow’s Milk is Added to Breast Milk and Sold to Parents Online 150 150 Katie Brind'Amour, PhD, MS, CHES
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Deceptive Internet advertisements for human breast milk may put infants at risk. What do parents (and doctors) need to know about milk sharing? A study published yesterday on the safety of human breast milk bought over the Internet found that 10 percent of samples contained added…

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The Continence Predictor Index
 The Continence Predictor Index 150 150 Marc Levitt, MD
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Are We Properly Capturing the Maternal-Child Health Continuum?
 Are We Properly Capturing the Maternal-Child Health Continuum? 150 150 Irina Buhimschi
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An obstetrician doing research at a children’s hospital may seem out of place. But not according to one clinician-scientist, who believes that maternal health and child health are inextricably intertwined. Traditionally, doctors divide into those who practice adult medicine and those who practice pediatrics.…

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Advancing Pediatric Anesthesiology Through Research
 Advancing Pediatric Anesthesiology Through Research 150 150 Joseph Tobias, MD
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Pediatric anesthesiology research is a relatively new phenomenon. But one clinician-scientist believes it is the key to bringing the field into the “big leagues” of evidence-based medicine. Over the past 30 years, the field of pediatric anesthesiology has expanded with the recognition of the…

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Big Data: Ride the Bandwagon, Sell Hot Dogs at the Show, or Jump Out of the Way?
 Big Data: Ride the Bandwagon, Sell Hot Dogs at the Show, or Jump Out of the Way? 150 150 William Ray, PhD
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Big Data has big potential. But can it truly tell you what you want to know? Big Data. It’s all the rage, and if you listen to the hype, you might get the impression that it’s going to cure cancer, bring about world peace…

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Early Detection of Bipolar Spectrum Disorders in High-Risk Children
 Early Detection of Bipolar Spectrum Disorders in High-Risk Children 150 150 Abbie Miller
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A new study finds key symptoms are associated with the development of bipolar disorder among children of parents with the condition. New research published today in the American Journal of Psychiatry indicates a strong link between subthreshold manic episodes and likelihood of developing bipolar disorder…

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Illuminating Vasospasm in Children with Traumatic Brain Injury
 Illuminating Vasospasm in Children with Traumatic Brain Injury 150 150 Jan Arthur
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Understanding reasons for dangerous vessel constriction following brain injury may help define treatment or prevention options. Vasospasm, or severe narrowing of blood vessels, is a dangerous complication observed in children with moderate to severe traumatic brain injury. In a paper recently published in Critical Care…

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Bacterial or Viral? New Technique to Clear Muddy Waters
 Bacterial or Viral? New Technique to Clear Muddy Waters 150 150 Jan Arthur
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Transcriptional profiling could help reduce inappropriate administration of antibiotics for lower respiratory infections in hospitalized patients. Lower respiratory tract infections (LRTIs) are one of the most frequent reasons for hospitalization in adults and children worldwide. However, in most cases, establishing the cause of the…

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Speeding Up the Genome Analysis Process
 Speeding Up the Genome Analysis Process 150 150 Jan Arthur
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New software analyzes human genomes faster than other available technologies, empowering population-scale genomic analysis. Investigators at Nationwide Children’s Hospital have developed an analysis “pipeline” that slashes the time it takes to search a person’s genome for disease-causing variations from weeks to hours. An article…

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Cholesterol Screening: What’s the Right Approach?
 Cholesterol Screening: What’s the Right Approach? 150 150 Dave Ghose
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The jury is still out on whether universal testing of children is a good thing. To screen or not to screen? For pediatricians, that question is far from answered when it comes to universal cholesterol testing. Despite an endorsement of the practice from an…

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How to Build and Lead a Successful Medical Department
 How to Build and Lead a Successful Medical Department 150 150 V. Rama Jayanthi, MD
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Fostering an environment that supports evidence-based medicine, professional development and equal footing for clinician-researchers is a critical challenge for medical leadership. You can spot the collaborative leader because he’s rejected the heroic, solitary model of leadership. He doesn’t try to dominate his organization as…

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Be Your Own Career Advocate
 Be Your Own Career Advocate 150 150 Linda Cripe, MD
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A successful cardiologist and neuromuscular disorders researcher shares her hard-won tips for getting what you want out of your career in academic medicine. The road to securing your first faculty position is long and frequently marked with significant personal and financial sacrifice. It is…

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Probing for Links Between Psychotropic Drugs and Severe Liver Disease
 Probing for Links Between Psychotropic Drugs and Severe Liver Disease 150 150 Kevin Mayhood
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Drugs that help minors with severe mental health disorders may put overweight and obese patients at risk for severe liver disease. In a paper that appears to be the first to suggest the connection, the authors point out that youths who suffer from psychiatric…

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Digital Education for Patients and Families
 Digital Education for Patients and Families 150 150 Mike Patrick, MD
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When patients and parents want health information, they often turn to the Internet. Let’s make sure they’re finding the right sources. In the digital age, young patients and their parents have an encyclopedic world of health information at their fingertips. Answers are available on…

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