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Brianne Moore

Care Bundles Can Reduce Hospital-Acquired Pressure Injuries
 Care Bundles Can Reduce Hospital-Acquired Pressure Injuries 150 150 Brianne Moore
By: Brianne Moore

Reliable implementation of care bundles reduces the number of serious hospital-acquired pressure injuries Hospital-acquired pressure injuries (PI) are a significant cause of preventable harm that can increase hospitalization costs and length of stay. Up to 27 percent of pediatric intensive care unit (PICU) patients and up to 23 percent of neonatal intensive care unit (NICU)…

Family Focus Restructures Single Ventricle Care
 Family Focus Restructures Single Ventricle Care 150 150 Brianne Moore
By: Brianne Moore

Standardize, connected care in a multidisciplinary team environment aims to improve outcomes and quality of life for patients born with single ventricle heart anatomy. Children with single ventricle anatomy, one of the most harrowing of congenital heart defects, face unique challenges that require multiple procedures and hospital admissions to treat. In most institutions, each admittance…

“Impatient” Therapy: Physicians Too Aggressive in Treatment of ITP
 “Impatient” Therapy: Physicians Too Aggressive in Treatment of ITP 150 150 Brianne Moore
By: Brianne Moore

Despite guidelines that advocate watching and waiting, physicians are still treating most patients with immune thrombocytopenia. When a child presents with easy bruising or bleeding, red skin spots and fatigue – symptoms similar to those for leukemia – families seek evaluation immediately. However, more often these cases are pediatric immune thrombocytopenia (ITP), an acquired disorder…

How to Improve Apparent Cause Analyses and Reduce Error Recurrence
 How to Improve Apparent Cause Analyses and Reduce Error Recurrence 150 150 Brianne Moore
By: Brianne Moore

A quality improvement team embarks on a project focused on the accuracy of future quality improvement initiatives. An apparent cause analysis (ACA) is a process used to investigate the cause or causes of a medium or low-risk safety event. Designed as a quality improvement measure, ACAs are used to explain in detail why an issue…

Emergency Departments Can Help Prevent Suicide
 Emergency Departments Can Help Prevent Suicide 150 150 Brianne Moore
By: Brianne Moore

Secondary screenings, safety plans and phone follow-ups are key to reducing death by suicide. Suicide is the tenth leading cause of death in the United States and has increased in incidence 27 percent from 1999 to 2015. Interestingly, up to 40 percent of individuals who die by suicide visit an emergency department (ED) in the…

Cannabidiol May Reduce Drug-Resistant Seizures by Half
 Cannabidiol May Reduce Drug-Resistant Seizures by Half 150 150 Brianne Moore
By: Brianne Moore

Two studies demonstrate clinically significant response to oral liquid cannabidiol over placebo. Two recent studies – one published in The New England Journal of Medicine and one presented at the 2017 American Academy of Neurology annual meeting – indicate that a new plant-based, cannabis-derived treatment may be able to decrease the incidence of seizures in two complex…

Specialists Collaborate to Improve Ovary Preservation
 Specialists Collaborate to Improve Ovary Preservation 150 150 Brianne Moore
By: Brianne Moore

A weekend case inspires an investigation into how pediatric surgeons and gynecologists treat the same patient differently. When lesions persist on a patient’s ovary, there are two options for treatment: oophorectomy, which removes the entire ovary, and ovarian sparing surgery (OSS). Depending on referral patterns and access to specialists, either a pediatric surgeon or a…

Meaningful Improvement of Child Health Requires Core Quality and Outcomes Measures
 Meaningful Improvement of Child Health Requires Core Quality and Outcomes Measures 150 150 Brianne Moore
By: Brianne Moore

The seemingly infinite indicators large pediatric systems use to measure children’s health often fall short in determining patient outcomes and quality of care. In an editorial published in JAMA Pediatrics, Kelly Kelleher, MD, director of the Center for Innovation in Pediatric Practice at Nationwide Children’s Hospital, and co-author William Gardner from the Children’s Hospital of Eastern Ontario, call for…

Math Model Reveals Immune System Secrets
 Math Model Reveals Immune System Secrets 150 150 Brianne Moore
By: Brianne Moore

Natural killer (NK) cells are a key part of the innate immune system, activating to destroy virally infected cells or tumor cells detected in the body. While the mechanism of detection of infected cells by NK cells is well understood, some aspects of how NK cells communicate with other immune cells are not. Due to…

Hepatitis E Persists and Self-Limits Due to Novel Mechanism, Study Finds
 Hepatitis E Persists and Self-Limits Due to Novel Mechanism, Study Finds 150 150 Brianne Moore
By: Brianne Moore

A team of researchers finds that Hepatitis E behaves uniquely compared other hepatitis viruses and hopes to pave the way for future investigation. Hepatitis E virus (HEV) is one of five known human hepatitis viruses and infects approximately 20 million people annually. HEV causes significant morbidity and mortality around the world, causing acute hepatitis in…

Secondary Findings: What Should Be Reported?
 Secondary Findings: What Should Be Reported? 150 150 Brianne Moore
By: Brianne Moore

With the growing use of exome and genome sequencing in research and diagnosis, the ACMG has recently released a policy update on the reporting of secondary findings. Genomic sequencing is instrumental in identifying many diseases. It can also reveal disease causing variants in our genetic code unrelated to the reason the clinical exome or genome…

Survey: Physical Barriers, Not Fear, Keep Homeless Youth From Receiving Care
 Survey: Physical Barriers, Not Fear, Keep Homeless Youth From Receiving Care 150 150 Brianne Moore
By: Brianne Moore

Research survey investigates barriers to care in unstably-housed youth. Every year, an estimated 1.6 to 1.7 million youth in the United States are living on the streets, in shelters or in other temporary living situations. Earlier studies have suggested that homeless youth do not seek medical services because of fear-based barriers – distrust of doctors,…

Great Minds Aren’t Thinking Alike About Asthma Care
 Great Minds Aren’t Thinking Alike About Asthma Care 150 150 Brianne Moore
By: Brianne Moore

A recent audit of the Pediatric Hospital Information System using template matching finds wide variation in care provided to pediatric asthma patients. While asthma is a common and manageable disease, nine people still die from asthma each day. It is well known that asthma is the leading cause of pediatric hospitalization as well as the…

Personal, Familial and Social Factors Surrounding Child Suicide
 Personal, Familial and Social Factors Surrounding Child Suicide 150 150 Brianne Moore
By: Brianne Moore

As suicide rates among children climb, researchers publish the first study exclusively focused on the precipitating circumstances of children and young adolescents who die by suicide. According to the Centers for Disease Control and Prevention (CDC), suicide was the 10th leading cause of death for children ages 5 to 11 in 2014. This was the first…

Finding a Better Way to Diagnose and Treat Iron Deficiency in Young Women
 Finding a Better Way to Diagnose and Treat Iron Deficiency in Young Women 150 150 Brianne Moore
By: Brianne Moore

Iron deficiency without anemia often goes undiagnosed in young women, and when caught, the standard treatment is often associated with poor compliance due to side effects. Dr. Sarah O’Brien’s research is focused on finding a solution. Even in developed countries, iron deficiency continues to be a prevalent nutritional disorder. It is common in women, especially…

Using Whole Exome Sequencing to Find Genetic Cause of Congenital Heart Disease in At-Risk Patients
 Using Whole Exome Sequencing to Find Genetic Cause of Congenital Heart Disease in At-Risk Patients 150 150 Brianne Moore
By: Brianne Moore

Whole exome sequencing has the ability to identify disease-causing mutations, contributing to the development of personalized medicine and bridging a crucial gap between scientific knowledge and clinical application. Congenital heart disease (CHD) is the most common type of birth defect, affecting approximately 40,000 births per year in the United States. While some types of CHD…

Counseling Pediatric Patients on Fertility and Sexual Function
 Counseling Pediatric Patients on Fertility and Sexual Function 150 150 Brianne Moore
By: Brianne Moore

How should we talk to patients and their families about these sensitive subjects? Since 2006, several medical societies have released guidelines for discussing fertility preservation prior to pediatric cancer treatment. According to the American Society for Reproductive Medicine, a “collaborative, multidisciplinary team approach” is vital for informing minors whose chemotherapy may affect their fertility status…