Hematology

What’s New in Pulmonary Care for Children With Sickle Cell Disease?
What’s New in Pulmonary Care for Children With Sickle Cell Disease? 1024 575 Erin Gregory
Illustration of lungs on blue silhouette of upper chest on black background

A recent publication reviews the impact of pulmonary complications on children and youth with sickle cell disease (SCD) and offers suggestions to improve outcomes. Pulmonary complications are a leading cause of morbidity and mortality in children with sickle cell disease (SCD), yet they remain underrecognized and undertreated. A recent review published in Clinics in Chest Medicine…

Increasing Use of Pharmacologic Clot Prevention Among Adolescents with Sickle Cell Disease
Increasing Use of Pharmacologic Clot Prevention Among Adolescents with Sickle Cell Disease 1024 580 Mary Bates, PhD

Growing interest in preventing thrombosis and approval of direct oral anticoagulants may be driving a shift to pharmacologic thromboprophylaxis. In a new study, researchers from Nationwide Children’s Hospital assessed the use of thromboprophylaxis in adolescent patients with sickle cell disease over the last decade. Sickle cell disease (SCD) increases the risk of venous thromboembolism (VTE).…

Fertility Concerns in Boys and Men With Sickle Cell Disease
Fertility Concerns in Boys and Men With Sickle Cell Disease 1024 575 Mary Bates, PhD
Color photo of Black father holding infant on shoulder in front of nursery background with clouds on the wall

Sickle cell disease and its treatments may impact fertility, but more research is needed to help counsel this population. Sickle cell disease (SCD) affects approximately 100,000 Americans, most of whom belong to underserved, minority populations. Advances in disease-modifying therapies, such as hydroxyurea, have led to better clinical outcomes. However, as more individuals with SCD survive…